ID F7BVX6_HORSE Unreviewed; 547 AA.
AC F7BVX6;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 2.
DT 27-MAR-2024, entry version 66.
DE RecName: Full=Zinc finger CCHC domain-containing protein 7 {ECO:0000256|ARBA:ARBA00041190};
DE AltName: Full=TRAMP-like complex RNA-binding factor ZCCHC7 {ECO:0000256|ARBA:ARBA00043023};
GN Name=ZCCHC7 {ECO:0000313|Ensembl:ENSECAP00000005026.2,
GN ECO:0000313|VGNC:VGNC:25181};
OS Equus caballus (Horse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000005026.2, ECO:0000313|Proteomes:UP000002281};
RN [1] {ECO:0000313|Ensembl:ENSECAP00000005026.2, ECO:0000313|Proteomes:UP000002281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000005026.2,
RC ECO:0000313|Proteomes:UP000002281};
RX PubMed=19892987; DOI=10.1126/science.1178158;
RG Broad Institute Genome Sequencing Platform;
RG Broad Institute Whole Genome Assembly Team;
RA Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
RA Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O.,
RA Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.,
RA Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T.,
RA Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S.,
RA Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G.,
RA Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R.,
RA Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A.,
RA Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J.,
RA Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
RT "Genome sequence, comparative analysis, and population genetics of the
RT domestic horse.";
RL Science 326:865-867(2009).
RN [2] {ECO:0000313|Ensembl:ENSECAP00000005026.2}
RP IDENTIFICATION.
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000005026.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_001504345.1; XM_001504295.2.
DR RefSeq; XP_005605686.1; XM_005605629.1.
DR AlphaFoldDB; F7BVX6; -.
DR STRING; 9796.ENSECAP00000005026; -.
DR PaxDb; 9796-ENSECAP00000005026; -.
DR Ensembl; ENSECAT00000006962.3; ENSECAP00000005026.2; ENSECAG00000006883.3.
DR GeneID; 100055202; -.
DR KEGG; ecb:100055202; -.
DR CTD; 84186; -.
DR VGNC; VGNC:25181; ZCCHC7.
DR GeneTree; ENSGT00950000183041; -.
DR HOGENOM; CLU_029787_0_0_1; -.
DR InParanoid; F7BVX6; -.
DR OMA; MRGHYAD; -.
DR OrthoDB; 3095763at2759; -.
DR TreeFam; TF329448; -.
DR Proteomes; UP000002281; Chromosome 25.
DR Bgee; ENSECAG00000006883; Expressed in trophectoderm and 23 other cell types or tissues.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR GO; GO:0031499; C:TRAMP complex; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0071031; P:nuclear mRNA surveillance of mRNA 3'-end processing; IBA:GO_Central.
DR GO; GO:0071039; P:nuclear polyadenylation-dependent CUT catabolic process; IBA:GO_Central.
DR GO; GO:0071035; P:nuclear polyadenylation-dependent rRNA catabolic process; IBA:GO_Central.
DR GO; GO:0071036; P:nuclear polyadenylation-dependent snoRNA catabolic process; IBA:GO_Central.
DR GO; GO:0071037; P:nuclear polyadenylation-dependent snRNA catabolic process; IBA:GO_Central.
DR GO; GO:0071038; P:nuclear polyadenylation-dependent tRNA catabolic process; IBA:GO_Central.
DR Gene3D; 4.10.60.10; Zinc finger, CCHC-type; 2.
DR InterPro; IPR001878; Znf_CCHC.
DR InterPro; IPR036875; Znf_CCHC_sf.
DR PANTHER; PTHR46543; ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 7; 1.
DR PANTHER; PTHR46543:SF1; ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 7; 1.
DR Pfam; PF00098; zf-CCHC; 1.
DR SMART; SM00343; ZnF_C2HC; 4.
DR SUPFAM; SSF57756; Retrovirus zinc finger-like domains; 2.
DR PROSITE; PS50158; ZF_CCHC; 2.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Reference proteome {ECO:0000313|Proteomes:UP000002281};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00047}.
FT DOMAIN 243..257
FT /note="CCHC-type"
FT /evidence="ECO:0000259|PROSITE:PS50158"
FT DOMAIN 350..365
FT /note="CCHC-type"
FT /evidence="ECO:0000259|PROSITE:PS50158"
FT REGION 52..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 406..547
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 406..425
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 434..477
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 501..538
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 547 AA; 64092 MW; 251425446E06BD9A CRC64;
MMFGGYETIE AYEDDLYREE SSSELSVDSE VEFQLYSQVH YAQDLRNVIR EEEHEEKNSG
NSESSSSKPN QKNLIILSDS EVIQLSDGSE VITLSDEDSI YRCTRKNFRV QAKEKTHSPP
ASLHSNELAD KKCKRDIEKP KPEERSGTIR EVMIIEVSSS EEEESTISDS DNVESWMLLG
CEVDDKDDDI LLNLVGCEKS VNEGEDGVNW FISDKDVEAQ IGNNRSSGRW THRYYSANKN
VTCRNCDRCG HLSKNCPFPQ KVRPCCLCSE RGHLQYACPA RFCLDCSLPM SSTHRCLERP
SWRKRCDRCD MIGHHADACP EIWRQYHLTT KPGPPKKPKT PSGQSALVYC YNCGQEGHYG
HECAERRMFN QTFPTSPFIY YYDDKYEIRE REQRIKRKVK ELQKNGDFPR QFKRPHMEAA
EKRAHRDVRK RHASWKTNRW PQEEQETQKE MMSRSKRERE KHRKADRCRK VDEDFPRGPQ
IRSSPSALRA QKPHRPFQHS SHYRQPREDR LPREGRRGKH RKKESHSEDD GSDHLLLIKQ
RRKKSKL
//
