ID F7BXT3_MOUSE Unreviewed; 257 AA.
AC F7BXT3;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 8.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=Lysine (K)-specific demethylase 5C {ECO:0000313|Ensembl:ENSMUSP00000122750.2};
DE Flags: Fragment;
GN Name=Kdm5c {ECO:0000313|Ensembl:ENSMUSP00000122750.2,
GN ECO:0000313|MGI:MGI:99781};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000122750.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000122750.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000122750.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000122750.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000122750.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F7BXT3; -.
DR PeptideAtlas; F7BXT3; -.
DR ProteomicsDB; 355581; -.
DR Antibodypedia; 26540; 257 antibodies from 31 providers.
DR Ensembl; ENSMUST00000156114.2; ENSMUSP00000122750.2; ENSMUSG00000025332.15.
DR AGR; MGI:99781; -.
DR MGI; MGI:99781; Kdm5c.
DR VEuPathDB; HostDB:ENSMUSG00000025332; -.
DR GeneTree; ENSGT00940000161236; -.
DR HOGENOM; CLU_951682_0_0_1; -.
DR ChiTaRS; Kdm5c; mouse.
DR Proteomes; UP000000589; Chromosome X.
DR Bgee; ENSMUSG00000025332; Expressed in epithelium of lens and 238 other cell types or tissues.
DR ExpressionAtlas; F7BXT3; baseline and differential.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR013637; Lys_sp_deMease-like_dom.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR Pfam; PF00628; PHD; 1.
DR Pfam; PF08429; PLU-1; 1.
DR SMART; SM00249; PHD; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
PE 1: Evidence at protein level;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Proteomics identification {ECO:0007829|EPD:F7BXT3,
KW ECO:0007829|MaxQB:F7BXT3};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 117..178
FT /note="Zinc finger PHD-type"
FT /evidence="ECO:0000259|SMART:SM00249"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000122750.2"
FT NON_TER 257
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000122750.2"
SQ SEQUENCE 257 AA; 28669 MW; 902B2C88D9E0F582 CRC64;
ALAKARAWIA DVDEIQNGDH YPCLDDLEGL VAVGRDLPVG LEELRQLELQ VLTAHSWREK
ASKTFLKKNS CYTLLEIVAF KEGEQKEKEG ILQLRRTNSA KPSPLALLTT ASSTASICVC
GQVPAGVGAL QCDLCQDWFH GRCVTVPRLL SSQRSSLPSS PLLAWWEWDT KFLCPLCMRS
RRPRLETILA LLVALQRLPV RLPEGEALQC LTERAISWQG RARQVLASEE VTALLGRLAE
LRQRLQAESK PEESLAY
//
