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Database: UniProt
Entry: F7BZF9_ORNAN
LinkDB: F7BZF9_ORNAN
Original site: F7BZF9_ORNAN 
ID   F7BZF9_ORNAN            Unreviewed;       361 AA.
AC   F7BZF9;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   27-JUL-2011, sequence version 1.
DT   16-OCT-2019, entry version 53.
DE   SubName: Full=Potassium voltage-gated channel subfamily J member 13 {ECO:0000313|Ensembl:ENSOANP00000012390};
GN   Name=KCNJ13 {ECO:0000313|Ensembl:ENSOANP00000012390};
OS   Ornithorhynchus anatinus (Duckbill platypus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus.
OX   NCBI_TaxID=9258 {ECO:0000313|Ensembl:ENSOANP00000012390, ECO:0000313|Proteomes:UP000002279};
RN   [1] {ECO:0000313|Ensembl:ENSOANP00000012390}
RP   IDENTIFICATION.
RC   STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000012390};
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   RefSeq; XP_007662339.1; XM_007664149.1.
DR   RefSeq; XP_007662340.1; XM_007664150.1.
DR   STRING; 9258.ENSOANP00000012390; -.
DR   Ensembl; ENSOANT00000012392; ENSOANP00000012390; ENSOANG00000007779.
DR   GeneID; 103169122; -.
DR   KEGG; oaa:103169122; -.
DR   CTD; 3769; -.
DR   eggNOG; KOG3827; Eukaryota.
DR   eggNOG; ENOG410XQ62; LUCA.
DR   GeneTree; ENSGT00960000186620; -.
DR   InParanoid; F7BZF9; -.
DR   KO; K05006; -.
DR   OMA; CVKHITS; -.
DR   OrthoDB; 956263at2759; -.
DR   TreeFam; TF313676; -.
DR   Proteomes; UP000002279; Unplaced.
DR   Bgee; ENSOANG00000007779; Expressed in 3 organ(s), highest expression level in cerebellum.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IBA:GO_Central.
DR   GO; GO:1990573; P:potassium ion import across plasma membrane; IBA:GO_Central.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR008062; KCNJ13.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   PANTHER; PTHR11767:SF3; PTHR11767:SF3; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PIRSF; PIRSF005465; GIRK_kir; 1.
DR   PRINTS; PR01679; KIR7CHANNEL.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002279};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002279};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     57     80       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    136    160       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       22    165       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      172    325       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   SITE        151    151       Role in the control of polyamine-mediated
FT                                channel gating and in the blocking by
FT                                intracellular magnesium.
FT                                {ECO:0000256|PIRSR:PIRSR005465-1}.
SQ   SEQUENCE   361 AA;  40685 MW;  48D3C1590AF44D05 CRC64;
     MTDGSKSKTT APLLTQRYQR MVTKDGHSTL QMDGAQRRGL AYLRDAWGIL MDMRWRWMML
     VFSASFVIHW LLFAVLWYVL AEMNGDLELD HDAPPENHTI CVKYITSFTA AFSFSLETQL
     TIGYGTMFPS GDCPSAIALL AIQMLLGLML EAFITGAFVA KIARPKNRAF SIRFTYSAVV
     AHTDGQPNLI FQVANTRPSP LTSVRVSAVL YQERENGKLY QTTVDFHLDN VSTEECPFFI
     FPLTYHHPIT SSSPLATLLR QETPHHFELV IFLSATQEGT GETCQRRTSY LPSEIMLHHC
     FASVLTRGSK GEYQIKMENF DKTIPELPAA DSKSPERTDL EIRINGQHID NFQISDLGLV
     G
//
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