ID F7C6C7_XENTR Unreviewed; 405 AA.
AC F7C6C7;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 4.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Alpha-macroglobulin receptor-binding domain-containing protein {ECO:0000259|SMART:SM01361};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000015231};
RN [1] {ECO:0000313|Ensembl:ENSXETP00000015231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000015231};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [2] {ECO:0000313|Ensembl:ENSXETP00000015231}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUN-2011) to UniProtKB.
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DR AlphaFoldDB; F7C6C7; -.
DR Ensembl; ENSXETT00000015231; ENSXETP00000015231; ENSXETG00000010226.
DR eggNOG; KOG1366; Eukaryota.
DR HOGENOM; CLU_071979_0_0_1; -.
DR InParanoid; F7C6C7; -.
DR TreeFam; TF313285; -.
DR Bgee; ENSXETG00000010226; Expressed in liver and 7 other cell types or tissues.
DR ExpressionAtlas; F7C6C7; baseline.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR Gene3D; 1.50.10.20; -; 3.
DR Gene3D; 2.60.120.1540; -; 1.
DR Gene3D; 2.60.40.690; Alpha-macroglobulin, receptor-binding domain; 2.
DR InterPro; IPR009048; A-macroglobulin_rcpt-bd.
DR InterPro; IPR036595; A-macroglobulin_rcpt-bd_sf.
DR InterPro; IPR047565; Alpha-macroglob_thiol-ester_cl.
DR InterPro; IPR011626; Alpha-macroglobulin_TED.
DR InterPro; IPR019742; MacrogloblnA2_CS.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR PANTHER; PTHR11412; MACROGLOBULIN / COMPLEMENT; 1.
DR PANTHER; PTHR11412:SF177; PROLACTIN-INDUCED PROTEIN; 1.
DR Pfam; PF07677; A2M_recep; 1.
DR Pfam; PF07678; TED_complement; 3.
DR SMART; SM01361; A2M_recep; 1.
DR SMART; SM01419; Thiol-ester_cl; 1.
DR SUPFAM; SSF49410; Alpha-macroglobulin receptor domain; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 1.
DR PROSITE; PS00477; ALPHA_2_MACROGLOBULIN; 1.
PE 4: Predicted;
FT DOMAIN 332..402
FT /note="Alpha-macroglobulin receptor-binding"
FT /evidence="ECO:0000259|SMART:SM01361"
SQ SEQUENCE 405 AA; 45009 MW; 7A990405E829D289 CRC64;
MGTAMQNLDR LLAMPYGCGE QNMVLFAPNI FILQYLTKTL QLTPEIQSKA KRFLESGEGS
GSLVCFCYFP VLTAFVVKSF SKAHPYIFID GDQLSQSLTW LKDHRKRNGC FQSVGKLFNN
AMKVPPGQTC TLFQCRATAL YYNSPNTLPA EIHFFLVYTQ ALLAYTFTLS NNTELREMLL
AKLEEKAVRK GTELVSSEVE LTSYVLLALL SGPNKDLGKA SEIVNWLSKQ QNPHGGFSST
QDTVVALQAL AEYAEATFSD KGDVTVTVTS KTGFHQQFHV DQTNRLLLQK ASLPDIPGEY
SLSATGSGCV YVQNESHGCF SSCRYTGSRE KSNMALVEVK MLSGFTPDKK SIDQVSDCPA
EQGYLGRHPV NFSFMVEQEV LVKNLRPAIV KVYDYYEPGK ELLSN
//
