ID F7CPG4_MONDO Unreviewed; 461 AA.
AC F7CPG4;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=Mitochondrial elongation factor 1 {ECO:0000256|ARBA:ARBA00041786};
DE AltName: Full=Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like {ECO:0000256|ARBA:ARBA00043160};
GN Name=MIEF1 {ECO:0000313|Ensembl:ENSMODP00000011733.3};
OS Monodelphis domestica (Gray short-tailed opossum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Didelphimorphia; Didelphidae; Monodelphis.
OX NCBI_TaxID=13616 {ECO:0000313|Ensembl:ENSMODP00000011733.3, ECO:0000313|Proteomes:UP000002280};
RN [1] {ECO:0000313|Ensembl:ENSMODP00000011733.3, ECO:0000313|Proteomes:UP000002280}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=17495919; DOI=10.1038/nature05805;
RA Mikkelsen T.S., Wakefield M.J., Aken B., Amemiya C.T., Chang J.L., Duke S.,
RA Garber M., Gentles A.J., Goodstadt L., Heger A., Jurka J., Kamal M.,
RA Mauceli E., Searle S.M., Sharpe T., Baker M.L., Batzer M.A., Benos P.V.,
RA Belov K., Clamp M., Cook A., Cuff J., Das R., Davidow L., Deakin J.E.,
RA Fazzari M.J., Glass J.L., Grabherr M., Greally J.M., Gu W., Hore T.A.,
RA Huttley G.A., Kleber M., Jirtle R.L., Koina E., Lee J.T., Mahony S.,
RA Marra M.A., Miller R.D., Nicholls R.D., Oda M., Papenfuss A.T., Parra Z.E.,
RA Pollock D.D., Ray D.A., Schein J.E., Speed T.P., Thompson K.,
RA VandeBerg J.L., Wade C.M., Walker J.A., Waters P.D., Webber C.,
RA Weidman J.R., Xie X., Zody M.C., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Bloom T., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., MacCallum I., Graves J.A., Ponting C.P., Breen M.,
RA Samollow P.B., Lander E.S., Lindblad-Toh K.;
RT "Genome of the marsupial Monodelphis domestica reveals innovation in non-
RT coding sequences.";
RL Nature 447:167-177(2007).
RN [2] {ECO:0000313|Ensembl:ENSMODP00000011733.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F7CPG4; -.
DR Ensembl; ENSMODT00000011954.3; ENSMODP00000011733.3; ENSMODG00000009391.4.
DR eggNOG; KOG4542; Eukaryota.
DR GeneTree; ENSGT00390000013127; -.
DR HOGENOM; CLU_046803_0_0_1; -.
DR TreeFam; TF331032; -.
DR Proteomes; UP000002280; Chromosome 8.
DR Bgee; ENSMODG00000009391; Expressed in adult mammalian kidney and 17 other cell types or tissues.
DR ExpressionAtlas; F7CPG4; baseline.
DR GO; GO:0005741; C:mitochondrial outer membrane; IEA:InterPro.
DR GO; GO:0007005; P:mitochondrion organization; IEA:InterPro.
DR Gene3D; 1.10.1410.40; -; 1.
DR Gene3D; 3.30.460.90; -; 1.
DR InterPro; IPR024810; Mab-21-like.
DR InterPro; IPR045909; MID49/MID51.
DR InterPro; IPR049097; MID51-like_C.
DR PANTHER; PTHR16451:SF12; MITOCHONDRIAL DYNAMICS PROTEIN MID51; 1.
DR PANTHER; PTHR16451; MITOCHONDRIAL DYNAMICS PROTEINS 49/51 FAMILY MEMBER; 1.
DR Pfam; PF21297; MID51-like_C; 1.
DR SMART; SM01265; Mab-21; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000002280};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 29..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 155..347
FT /note="Mitochondrial dynamics protein MID51-like C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF21297"
FT REGION 58..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 94..129
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 461 AA; 51044 MW; 02780B3744BDA4C1 CRC64;
MAGTGERPGK GKKDDNGIGT AIDFVLSNAR LVLGVGGAAM LGIATLAVKR MYDRAISAPS
SPTRLSHSGK RSWEEPSWMG SSRLLKQDMK SNLSRSLQTL PTDPSAFDTD GFCSPRPKPA
SKRGQADLKK SRLRLSLQEK LFAYYRTRAA IPPGEQARAK QAAVDICAEL RSFLRAKLPD
MPLRDMYLSG SLYDDLQVVT ADHIQLIVPL VLEQNLWSCI PGEDTIMNIP GFFLVRRENP
EYFPRGSSYW DRCVVGGYLS PKAVAETFEK VVAGSINWPA IGSLLDYVIR PAPPPEALTL
EVQYEPQRRL VIDFLPSVTL GDTILWARPH RLAQYDNLWR LSLRPAETAR LRALDQGDSG
CRAVCLKVLK AICKSSPALG HLTASQLTNV ILHLAQEEPD WSQDMLADRF LQALRALIGY
LEAGVLPSAL NPKWKNGYLN LGCWIHGISE CKETLEISWG F
//
