ID F7CPM0_HORSE Unreviewed; 411 AA.
AC F7CPM0;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2023, sequence version 3.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=RNA binding motif single stranded interacting protein 1 {ECO:0000313|Ensembl:ENSECAP00000017800.3};
GN Name=RBMS1 {ECO:0000313|Ensembl:ENSECAP00000017800.3,
GN ECO:0000313|VGNC:VGNC:22253};
OS Equus caballus (Horse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000017800.3, ECO:0000313|Proteomes:UP000002281};
RN [1] {ECO:0000313|Ensembl:ENSECAP00000017800.3, ECO:0000313|Proteomes:UP000002281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000017800.3,
RC ECO:0000313|Proteomes:UP000002281};
RX PubMed=19892987; DOI=10.1126/science.1178158;
RG Broad Institute Genome Sequencing Platform;
RG Broad Institute Whole Genome Assembly Team;
RA Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
RA Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O.,
RA Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.,
RA Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T.,
RA Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S.,
RA Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G.,
RA Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R.,
RA Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A.,
RA Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J.,
RA Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
RT "Genome sequence, comparative analysis, and population genetics of the
RT domestic horse.";
RL Science 326:865-867(2009).
RN [2] {ECO:0000313|Ensembl:ENSECAP00000017800.3}
RP IDENTIFICATION.
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000017800.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_014587990.1; XM_014732504.1.
DR AlphaFoldDB; F7CPM0; -.
DR STRING; 9796.ENSECAP00000017800; -.
DR PaxDb; 9796-ENSECAP00000017800; -.
DR Ensembl; ENSECAT00000021603.3; ENSECAP00000017800.3; ENSECAG00000019894.4.
DR GeneID; 100060392; -.
DR KEGG; ecb:100060392; -.
DR VGNC; VGNC:22253; RBMS1.
DR GeneTree; ENSGT00940000156082; -.
DR HOGENOM; CLU_016278_2_0_1; -.
DR InParanoid; F7CPM0; -.
DR OMA; GWAMIFP; -.
DR OrthoDB; 129910at2759; -.
DR TreeFam; TF314644; -.
DR Proteomes; UP000002281; Chromosome 18.
DR Bgee; ENSECAG00000019894; Expressed in synovial membrane of synovial joint and 23 other cell types or tissues.
DR ExpressionAtlas; F7CPM0; baseline.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:1990904; C:ribonucleoprotein complex; IBA:GO_Central.
DR GO; GO:0003730; F:mRNA 3'-UTR binding; IBA:GO_Central.
DR GO; GO:0008143; F:poly(A) binding; IBA:GO_Central.
DR GO; GO:0008266; F:poly(U) RNA binding; IBA:GO_Central.
DR CDD; cd12470; RRM1_MSSP1; 1.
DR CDD; cd12473; RRM2_MSSP1; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR InterPro; IPR002343; Hud_Sxl_RNA.
DR InterPro; IPR034404; MSSP1_RRM1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR24012; RNA BINDING PROTEIN; 1.
DR PANTHER; PTHR24012:SF702; RNA-BINDING MOTIF, SINGLE-STRANDED-INTERACTING PROTEIN 1; 1.
DR Pfam; PF00076; RRM_1; 2.
DR PRINTS; PR00961; HUDSXLRNA.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50102; RRM; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002281};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 51..124
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 130..215
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 17..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 27..45
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 411 AA; 44803 MW; 3F534C56D6BCC077 CRC64;
MALNEFRCDT GILKQSLVPA HPMAPPSPST TSSNNNSSSS SNSGWDQLSK TNLYIRGLPP
NTTDQDLVKL CQPYGKIVST KAILDKTTNK CKGYGFVDFD SPAAAQKAVS ALKANGVQAQ
MAKQQEQDPT NLYISNLPLS MDEQELENML KPFGQVISTR ILRDSSGTSR GVGFARMEST
EKCEAVIGHF NGKFIKTPPG VSAPTEPLLC KFADGGQKKR QNPNKYIPNG RPWHREGEVR
LAGMTLTYDP TTAAIQNGFY PSPYSIATNR MITQTSITPY IASPVSAYQV AKETRENKYR
GSAIKVQSPS WMQPQPYILQ HPGAVLTPSM EHTMSLQPTS MISPLAQQMS HLSLGSTGTY
MPATSAMQGA YLPQYTHVQT TAVPVEEASG QQQVAVETSN DHSPYTFQPN K
//
