ID F7D2X7_CALJA Unreviewed; 571 AA.
AC F7D2X7;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=AP complex subunit beta {ECO:0000256|PIRNR:PIRNR002291};
GN Name=AP4B1 {ECO:0000313|Ensembl:ENSCJAP00000044269.1};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000044269.1, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000044269.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000044269.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the adaptor complexes large subunit family.
CC {ECO:0000256|ARBA:ARBA00006613, ECO:0000256|PIRNR:PIRNR002291}.
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DR AlphaFoldDB; F7D2X7; -.
DR Ensembl; ENSCJAT00000053084.4; ENSCJAP00000044269.1; ENSCJAG00000012178.5.
DR GeneTree; ENSGT00940000157025; -.
DR Proteomes; UP000008225; Chromosome 7.
DR Bgee; ENSCJAG00000012178; Expressed in cerebellum and 6 other cell types or tissues.
DR GO; GO:0030131; C:clathrin adaptor complex; IEA:InterPro.
DR GO; GO:0031410; C:cytoplasmic vesicle; IEA:UniProt.
DR GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.30.310.10; TATA-Binding Protein; 1.
DR InterPro; IPR026739; AP_beta.
DR InterPro; IPR016342; AP_complex_bsu_1_2_4.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR015151; B-adaptin_app_sub_C.
DR InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR InterPro; IPR012295; TBP_dom_sf.
DR PANTHER; PTHR11134; ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER; 1.
DR PANTHER; PTHR11134:SF4; AP-4 COMPLEX SUBUNIT BETA-1; 1.
DR Pfam; PF01602; Adaptin_N; 1.
DR Pfam; PF09066; B2-adapt-app_C; 1.
DR PIRSF; PIRSF002291; AP_complex_beta; 2.
DR SMART; SM01020; B2-adapt-app_C; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR002291};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR002291};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR002291}.
FT DOMAIN 452..564
FT /note="Beta-adaptin appendage C-terminal subdomain"
FT /evidence="ECO:0000259|SMART:SM01020"
SQ SEQUENCE 571 AA; 64554 MW; 788F7B67F5797EFE CRC64;
MPYLGSEDVV KELKKALCNP HIQADRLRYR NVIQRVIRMS KLDQWGQAEV LNFLLRYQPR
SEEELFDILN LLDSFLKSGS PGVVMGATKL FLILAKKFPH VQTDVLVRVK GPLLAACSSE
SRELCFVALC HVRQILHSLP GHFSSHYKKF FCSYSEPHYI KLQKVEVLCE LVNDENVQQV
LEELRGYCTD VSADFAQAAI FAIGGIARTY TDQCVQILTE LLGLRQEHIT TVVVQTFRDL
VWLCPQCTEA VCQALPGCEE NIQDSEGKQA LIWLLGVHGE RIPNAPYVLE DFVENVKSET
FPAVKMELLT ALMRLFLSRP AECQDMLGRL LYYCIEEEKD MAVRDRGLFY YRLLLVGIDE
VKRILCSPKS DPTLGLLEDP AERPVNSWAS DFNTLVPVYG KSRWATISKC QGAERCGPEL
PKTPSFTASG PLIPEENKER VQELPDSGAL MLVPNLQLTA DYFEKTWLSL KVAHQQVLPW
QGEFHPDTLQ MALQVVNIQT IAMSRAGARP WKAYLSAQDD TGCLFLTELL LTSENSEMQI
SVKQNETRTE TLNSFISVLE TVIGTIEEIK S
//
