ID F7D7X0_MACMU Unreviewed; 663 AA.
AC F7D7X0; A0A5S6RA57; F6YTP9; G7NK38;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Rubicon like autophagy enhancer {ECO:0000313|Ensembl:ENSMMUP00000015079.4};
GN Name=RUBCNL {ECO:0000313|Ensembl:ENSMMUP00000015079.4,
GN ECO:0000313|VGNC:VGNC:77063};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|Ensembl:ENSMMUP00000015079.4, ECO:0000313|Proteomes:UP000006718};
RN [1] {ECO:0000313|Proteomes:UP000006718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=17573 {ECO:0000313|Proteomes:UP000006718};
RX PubMed=17431167; DOI=10.1126/science.1139247;
RA Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M.,
RA Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., Wilson R.K.,
RA Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., Hardison R.C.,
RA Makova K.D., Miller W., Milosavljevic A., Palermo R.E., Siepel A.,
RA Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J.,
RA Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., Dinh H.H.,
RA Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., Godfrey J.,
RA Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N.,
RA Joshi V., Khan Z.M., Kirkness E.F., Cree A., Fowler R.G., Lee S.,
RA Lewis L.R., Li Z., Liu Y.-S., Moore S.M., Muzny D., Nazareth L.V.,
RA Ngo D.N., Okwuonu G.O., Pai G., Parker D., Paul H.A., Pfannkoch C.,
RA Pohl C.S., Rogers Y.-H.C., Ruiz S.J., Sabo A., Santibanez J.,
RA Schneider B.W., Smith S.M., Sodergren E., Svatek A.F., Utterback T.R.,
RA Vattathil S., Warren W., White C.S., Chinwalla A.T., Feng Y., Halpern A.L.,
RA Hillier L.W., Huang X., Minx P., Nelson J.O., Pepin K.H., Qin X.,
RA Sutton G.G., Venter E., Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P.,
RA Jones S.M., Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L.,
RA Csuros M., Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H.,
RA Liu Y., Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E.,
RA Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J.,
RA Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J.,
RA Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A.,
RA Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., Denby A.,
RA Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., Marklein A.,
RA Nielsen R., Vallender E.J., Clark A.G., Ferguson B., Hernandez R.D.,
RA Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., Pu L.-L., Ren Y.,
RA Smith D.G., Wheeler D.A., Schenck I., Ball E.V., Chen R., Cooper D.N.,
RA Giardine B., Hsu F., Kent W.J., Lesk A., Nelson D.L., O'brien W.E.,
RA Pruefer K., Stenson P.D., Wallace J.C., Ke H., Liu X.-M., Wang P.,
RA Xiang A.P., Yang F., Barber G.P., Haussler D., Karolchik D., Kern A.D.,
RA Kuhn R.M., Smith K.E., Zwieg A.S.;
RT "Evolutionary and biomedical insights from the rhesus macaque genome.";
RL Science 316:222-234(2007).
RN [2] {ECO:0000313|Ensembl:ENSMMUP00000015079.4}
RP IDENTIFICATION.
RC STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000015079.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_014976533.1; XM_015121047.1.
DR PaxDb; 9544-ENSMMUP00000012915; -.
DR Ensembl; ENSMMUT00000013781.4; ENSMMUP00000012915.4; ENSMMUG00000009862.4.
DR Ensembl; ENSMMUT00000016089.4; ENSMMUP00000015079.4; ENSMMUG00000009862.4.
DR Ensembl; ENSMMUT00000079812.1; ENSMMUP00000061818.1; ENSMMUG00000009862.4.
DR GeneID; 703875; -.
DR CTD; 80183; -.
DR VEuPathDB; HostDB:ENSMMUG00000009862; -.
DR VGNC; VGNC:77063; RUBCNL.
DR GeneTree; ENSGT00940000160585; -.
DR HOGENOM; CLU_027575_0_0_1; -.
DR HOGENOM; CLU_969627_0_0_1; -.
DR OrthoDB; 126314at2759; -.
DR TreeFam; TF317067; -.
DR Proteomes; UP000006718; Chromosome 17.
DR Bgee; ENSMMUG00000009862; Expressed in ileum and 23 other cell types or tissues.
DR InterPro; IPR025258; RH_dom.
DR InterPro; IPR048569; RUBC_PIKBD.
DR PANTHER; PTHR45971; PHOX (PX) DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45971:SF2; PROTEIN ASSOCIATED WITH UVRAG AS AUTOPHAGY ENHANCER; 1.
DR Pfam; PF13901; RH_dom; 1.
DR Pfam; PF21054; RUBC_PIKBD; 1.
DR SMART; SM01175; DUF4206; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006718}.
FT DOMAIN 451..652
FT /note="Rubicon Homology"
FT /evidence="ECO:0000259|SMART:SM01175"
FT REGION 72..147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 663 AA; 73951 MW; FA033534DEC7B160 CRC64;
MVSQSTVRQD SPEDPWERIT HYSGIIDGPP GLLNTDHPPC QLDIRLMRHK AAWINPQDVQ
QQLQDLQPQV PAAGNSGTHF VTDAASPSGP SSSCLRDSLA ETTLSEATTD SIGSASPHGS
REKSSSFSLS STEGHMVHPG YSHQVSLPTS PRILVTSPYP ETDSAFFEPS HLTSAAAEDA
VQVSRRTISL NSFSPEVFVL PVDVEKENAH FHVADMIISA MEKMKCNILS QQQTENWSKE
EASGLLGSDQ PDSDVTFDTN IKQESGSSTS SYSGYEGCAV LQVSPVTETR PYPDVKEICQ
CDIDEFVILE LGDFNDITET CSCSCNSSKS VTYEPEFNSA ELLAKELYRV FRKCWMLSLV
NSQLAGSLSA AGSIVVNEER VRKNFESSMN VVQEIKFKSR IRGTEDWAPP RFQIIFNIHP
PLKRDLVVAA QNFFCAGCGT PIEPKFVKRL RYCEYLGKYF CDCCHSYAES CIPARILMMW
DFKKYYVSNF SKRLLDSIWN QPIFNLLSIG QSLYAKAKEL GRMKEIQEQL FHIKKLLKTC
RFADSALKEF EQVPGHLTDE LHLFSLEDLV RIKKGLLAPL LKDILKASLA HVAGCELCQG
KGFICEFCQN TTVIFPFQTA TCRRCSACRA CFHKQCFQSS ECPRCVRITA RRKLLESVAS
AAT
//
