ID F7DA96_HORSE Unreviewed; 760 AA.
AC F7DA96;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2023, sequence version 4.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Kinesin associated protein 3 {ECO:0000313|Ensembl:ENSECAP00000003939.4};
GN Name=KIFAP3 {ECO:0000313|Ensembl:ENSECAP00000003939.4,
GN ECO:0000313|VGNC:VGNC:19425};
OS Equus caballus (Horse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000003939.4, ECO:0000313|Proteomes:UP000002281};
RN [1] {ECO:0000313|Ensembl:ENSECAP00000003939.4, ECO:0000313|Proteomes:UP000002281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000003939.4,
RC ECO:0000313|Proteomes:UP000002281};
RX PubMed=19892987; DOI=10.1126/science.1178158;
RG Broad Institute Genome Sequencing Platform;
RG Broad Institute Whole Genome Assembly Team;
RA Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
RA Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O.,
RA Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.,
RA Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T.,
RA Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S.,
RA Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G.,
RA Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R.,
RA Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A.,
RA Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J.,
RA Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
RT "Genome sequence, comparative analysis, and population genetics of the
RT domestic horse.";
RL Science 326:865-867(2009).
RN [2] {ECO:0000313|Ensembl:ENSECAP00000003939.4}
RP IDENTIFICATION.
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000003939.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F7DA96; -.
DR STRING; 9796.ENSECAP00000003939; -.
DR PaxDb; 9796-ENSECAP00000003939; -.
DR Ensembl; ENSECAT00000005585.4; ENSECAP00000003939.4; ENSECAG00000002798.4.
DR VGNC; VGNC:19425; KIFAP3.
DR GeneTree; ENSGT00390000003574; -.
DR HOGENOM; CLU_009879_1_0_1; -.
DR InParanoid; F7DA96; -.
DR OMA; MYELNIV; -.
DR TreeFam; TF314964; -.
DR Proteomes; UP000002281; Chromosome 5.
DR Bgee; ENSECAG00000002798; Expressed in brainstem and 24 other cell types or tissues.
DR ExpressionAtlas; F7DA96; baseline.
DR GO; GO:0005930; C:axoneme; IBA:GO_Central.
DR GO; GO:0035869; C:ciliary transition zone; IBA:GO_Central.
DR GO; GO:0016939; C:kinesin II complex; IBA:GO_Central.
DR GO; GO:0019894; F:kinesin binding; IEA:InterPro.
DR GO; GO:0044782; P:cilium organization; IBA:GO_Central.
DR GO; GO:0007018; P:microtubule-based movement; IBA:GO_Central.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR008658; KAP3.
DR PANTHER; PTHR15605:SF2; KINESIN-ASSOCIATED PROTEIN 3; 1.
DR PANTHER; PTHR15605; KINESIN-ASSOCIATED PROTEINS; 1.
DR Pfam; PF05804; KAP; 1.
DR SMART; SM00185; ARM; 3.
DR SMART; SM01297; KAP; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002281}.
FT REPEAT 589..633
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REGION 103..124
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 103..123
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 760 AA; 87807 MW; A2C57A3A927B6E70 CRC64;
MQGEDARYLK RKVKGGNIDV HPSEKALIVH YEVEATILGE MGDPMLGERK ECQKIIRLKS
LNANTDITSL ARKVVEECKL IHPSKLSEVE QLLYYLQNRR DSLSGKEKKE KSSKPKDPPP
FEGMEIDEVA NINDMDEYIE LLYEDIPDKV RGSALILQLA RNPDNLEELL LNETALGALA
RVLREDWKQS VELATNIIYI FFCFSSFSQF HGLITHYKIG ALCMNIIDHE LKRHELWQEE
LSKKKKAVDE DPENQTLRKD YEKTFKKYQG LVVKQEQLLR VALYLLLNLA EDTRTELKMR
NKNIVHMLVK ALDRDNFELL ILVVSFLKKL SIFMENKNDM VEMDIVEKLV KMIPCEHEDL
LNITLRLLLN LSFDTGLRNK MVQVGLLPKL TALLGNENYK QIAMCVLYHI SMDDRFKSMF
AYTDCIPQLM KMLFECSDER IDLELISFCI NLAANKRNVQ LICEGNGLKM LMKRALKFKD
PLLMKMIRNI SQHDGPTKTL FIDYVGDLAA QISNDEEEEF VIECLGTLAN LTIPDLDWEL
VLKEYKLVPY LKDKLKPGAA EDDLVLEVVI MIGTVSMDDS CAALLAKSGI IPALIELLNA
QQEDDEFVCQ IIYVFYQMVF HQATRDVIIK ETQAPAYLID LMHDKNNEIR KVCDNTLDII
AEYDEEWAKK IQSEKFRWHN SQWLEMVESR QMDESEQYLY GDDRIEPYIH EGDILERPDL
FYNSDGLIAS EGAVSPDFFN DYHLQNGEIV GQHSFPGSLR
//
