ID F7DBI2_ORNAN Unreviewed; 405 AA.
AC F7DBI2;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE RecName: Full=G2/mitotic-specific cyclin-B2 {ECO:0000256|ARBA:ARBA00040980};
GN Name=CCNB2 {ECO:0000313|Ensembl:ENSOANP00000019482.1};
OS Ornithorhynchus anatinus (Duckbill platypus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Monotremata; Ornithorhynchidae; Ornithorhynchus.
OX NCBI_TaxID=9258 {ECO:0000313|Ensembl:ENSOANP00000019482.1, ECO:0000313|Proteomes:UP000002279};
RN [1] {ECO:0000313|Ensembl:ENSOANP00000019482.1}
RP IDENTIFICATION.
RC STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000019482.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Essential for the control of the cell cycle at the G2/M
CC (mitosis) transition. {ECO:0000256|ARBA:ARBA00003222}.
CC -!- SIMILARITY: Belongs to the cyclin family. Cyclin AB subfamily.
CC {ECO:0000256|ARBA:ARBA00006955}.
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DR RefSeq; XP_007654322.1; XM_007656132.2.
DR AlphaFoldDB; F7DBI2; -.
DR STRING; 9258.ENSOANP00000019482; -.
DR Ensembl; ENSOANT00000019485.3; ENSOANP00000019482.1; ENSOANG00000012313.3.
DR GeneID; 100091100; -.
DR KEGG; oaa:100091100; -.
DR CTD; 9133; -.
DR eggNOG; KOG0653; Eukaryota.
DR GeneTree; ENSGT00940000155405; -.
DR HOGENOM; CLU_020695_2_1_1; -.
DR InParanoid; F7DBI2; -.
DR OMA; QPTKTNV; -.
DR OrthoDB; 5474295at2759; -.
DR TreeFam; TF101001; -.
DR Proteomes; UP000002279; Unplaced.
DR Bgee; ENSOANG00000012313; Expressed in testis and 7 other cell types or tissues.
DR GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR GO; GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0016020; C:membrane; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IBA:GO_Central.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0008315; P:G2/MI transition of meiotic cell cycle; IEA:Ensembl.
DR GO; GO:0044772; P:mitotic cell cycle phase transition; IBA:GO_Central.
DR GO; GO:0040008; P:regulation of growth; IEA:Ensembl.
DR GO; GO:0007057; P:spindle assembly involved in female meiosis I; IEA:Ensembl.
DR GO; GO:0043029; P:T cell homeostasis; IEA:Ensembl.
DR GO; GO:0048538; P:thymus development; IEA:Ensembl.
DR Gene3D; 1.10.472.10; Cyclin-like; 2.
DR InterPro; IPR039361; Cyclin.
DR InterPro; IPR013763; Cyclin-like_dom.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR046965; Cyclin_A/B-like.
DR InterPro; IPR004367; Cyclin_C-dom.
DR InterPro; IPR006671; Cyclin_N.
DR InterPro; IPR048258; Cyclins_cyclin-box.
DR PANTHER; PTHR10177; CYCLINS; 1.
DR PANTHER; PTHR10177:SF184; G2_MITOTIC-SPECIFIC CYCLIN-B2; 1.
DR Pfam; PF02984; Cyclin_C; 1.
DR Pfam; PF00134; Cyclin_N; 1.
DR PIRSF; PIRSF001771; Cyclin_A_B_D_E; 2.
DR SMART; SM00385; CYCLIN; 2.
DR SMART; SM01332; Cyclin_C; 1.
DR SUPFAM; SSF47954; Cyclin-like; 2.
DR PROSITE; PS00292; CYCLINS; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Cyclin {ECO:0000256|ARBA:ARBA00023127, ECO:0000256|RuleBase:RU000383};
KW Reference proteome {ECO:0000313|Proteomes:UP000002279}.
FT DOMAIN 178..262
FT /note="Cyclin-like"
FT /evidence="ECO:0000259|SMART:SM00385"
FT DOMAIN 271..389
FT /note="Cyclin C-terminal"
FT /evidence="ECO:0000259|SMART:SM01332"
FT DOMAIN 275..356
FT /note="Cyclin-like"
FT /evidence="ECO:0000259|SMART:SM00385"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 79..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 80..100
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 405 AA; 45093 MW; BF42C04064E63885 CRC64;
MALLRRHPAS RGLENADPEI QLKPKSHVTV RRGRPALGEI GNKVANRGVP VAKKAGSTKL
PVTSTKGIVK ATNVTAPKLP VPGRPVPKEA AVPKAPSPEP APMDVSMSEE ALCQAFSDKL
LCSVEDIDGE DGGNPQLCSD YVKEIYQYLR QLEVQQSIHP NFLDGRELNG RMRAILVDWL
VQVHSKFRLL QETLYMCVAI MDRFLQAQPV SRKKLQLVGV TALLLASKYE EIFSPDIRDF
VYITDQTYTS SQIREMEVLI LSELKFELGR PLPLHFLRRA SKAGEADAEQ HTLAKYLMEL
TIVDYDMAHY PPSAVAAAAS CLSQKILGQG EWSPKQRYYT GYSEEEVWEV MQHMAKNVAK
VNGNLNKFIA VKNKYASSKL MKISTIPQLN SKTIQDLAQP LLGRG
//
