ID F7DJZ1_HORSE Unreviewed; 496 AA.
AC F7DJZ1;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2023, sequence version 4.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=Lipid-binding serum glycoprotein N-terminal domain-containing protein {ECO:0000259|SMART:SM00328};
GN Name=LOC106781244 {ECO:0000313|Ensembl:ENSECAP00000012279.4};
OS Equus caballus (Horse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000012279.4, ECO:0000313|Proteomes:UP000002281};
RN [1] {ECO:0000313|Ensembl:ENSECAP00000012279.4, ECO:0000313|Proteomes:UP000002281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000012279.4,
RC ECO:0000313|Proteomes:UP000002281};
RX PubMed=19892987; DOI=10.1126/science.1178158;
RG Broad Institute Genome Sequencing Platform;
RG Broad Institute Whole Genome Assembly Team;
RA Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
RA Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O.,
RA Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.,
RA Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T.,
RA Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S.,
RA Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G.,
RA Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R.,
RA Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A.,
RA Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J.,
RA Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
RT "Genome sequence, comparative analysis, and population genetics of the
RT domestic horse.";
RL Science 326:865-867(2009).
RN [2] {ECO:0000313|Ensembl:ENSECAP00000012279.4}
RP IDENTIFICATION.
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000012279.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; F7DJZ1; -.
DR Ensembl; ENSECAT00000015294.4; ENSECAP00000012279.4; ENSECAG00000014407.4.
DR GeneTree; ENSGT01100000263546; -.
DR HOGENOM; CLU_050473_0_0_1; -.
DR TreeFam; TF338541; -.
DR Proteomes; UP000002281; Chromosome 22.
DR Bgee; ENSECAG00000014407; Expressed in epithelium of bronchus.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR CDD; cd00025; BPI1; 1.
DR InterPro; IPR017943; Bactericidal_perm-incr_a/b_dom.
DR InterPro; IPR021193; Bpifb1.
DR InterPro; IPR001124; Lipid-bd_serum_glycop_C.
DR InterPro; IPR017942; Lipid-bd_serum_glycop_N.
DR PANTHER; PTHR47395; BPI FOLD-CONTAINING FAMILY B MEMBER 1; 1.
DR PANTHER; PTHR47395:SF1; BPI FOLD-CONTAINING FAMILY B MEMBER 1; 1.
DR Pfam; PF01273; LBP_BPI_CETP; 1.
DR Pfam; PF02886; LBP_BPI_CETP_C; 1.
DR PIRSF; PIRSF037186; PLUNC_long_form; 1.
DR SMART; SM00328; BPI1; 1.
DR SUPFAM; SSF55394; Bactericidal permeability-increasing protein, BPI; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002281}.
FT DOMAIN 58..278
FT /note="Lipid-binding serum glycoprotein N-terminal"
FT /evidence="ECO:0000259|SMART:SM00328"
SQ SEQUENCE 496 AA; 54296 MW; 4907BD51AEC7B2BD CRC64;
MTHQQPQRRG FRCLPPATTD PRKMAGPWTF ALCGLLAATL VRATLSPAAV LSLSPEVIEG
KLTQKLEDHD AVDILWRLPL LSTMREKPAG GNPILGSLVT FLMKYIIWLK VTSANILQLQ
IQPSADGQEL VVKVPLDMVA GFNTPLVKSI VEMHMETEAQ AIIRVETSER GGTLVLRNCS
NSPGSLRLSL LRRFSFLVNS LADKVMSFLL PTLPTLVKSQ LCPVIEAAFE DMREDLLRLV
RVPVSLSSGH LQFDLLSPAI KHDVIQLHLQ AKLSDSQGKV TKWFNESAVS LTMPTLEGEP
FSLTIRQDVV NAAVAALVPP EELMVLLDYV LPELALRLKS SMKVISETAA DQLGPTQIVK
IVTQETPELL LDQGRAKVVQ LIVLEVFATS EVRRPFFTLG IEASSEAWFY TKGDRLMLNL
NQISTDRIHL MNSGIGLFNP ELLKDITAEM LTSAMLPNEN GKLSSGISMS MVKALGFEAA
SCSLTNDALV VTPASS
//
