GenomeNet

Database: UniProt
Entry: F7DPE0_ORNAN
LinkDB: F7DPE0_ORNAN
Original site: F7DPE0_ORNAN 
ID   F7DPE0_ORNAN            Unreviewed;      2623 AA.
AC   F7DPE0;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   27-JUL-2011, sequence version 1.
DT   05-DEC-2018, entry version 44.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSOANP00000017850};
OS   Ornithorhynchus anatinus (Duckbill platypus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus.
OX   NCBI_TaxID=9258 {ECO:0000313|Ensembl:ENSOANP00000017850, ECO:0000313|Proteomes:UP000002279};
RN   [1] {ECO:0000313|Proteomes:UP000002279}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Glennie {ECO:0000313|Proteomes:UP000002279};
RX   PubMed=18464734; DOI=10.1038/nature06936;
RA   Warren W.C., Hillier L.W., Marshall Graves J.A., Birney E.,
RA   Ponting C.P., Grutzner F., Belov K., Miller W., Clarke L.,
RA   Chinwalla A.T., Yang S.P., Heger A., Locke D.P., Miethke P.,
RA   Waters P.D., Veyrunes F., Fulton L., Fulton B., Graves T., Wallis J.,
RA   Puente X.S., Lopez-Otin C., Ordonez G.R., Eichler E.E., Chen L.,
RA   Cheng Z., Deakin J.E., Alsop A., Thompson K., Kirby P.,
RA   Papenfuss A.T., Wakefield M.J., Olender T., Lancet D., Huttley G.A.,
RA   Smit A.F., Pask A., Temple-Smith P., Batzer M.A., Walker J.A.,
RA   Konkel M.K., Harris R.S., Whittington C.M., Wong E.S., Gemmell N.J.,
RA   Buschiazzo E., Vargas Jentzsch I.M., Merkel A., Schmitz J., Zemann A.,
RA   Churakov G., Kriegs J.O., Brosius J., Murchison E.P.,
RA   Sachidanandam R., Smith C., Hannon G.J., Tsend-Ayush E., McMillan D.,
RA   Attenborough R., Rens W., Ferguson-Smith M., Lefevre C.M., Sharp J.A.,
RA   Nicholas K.R., Ray D.A., Kube M., Reinhardt R., Pringle T.H.,
RA   Taylor J., Jones R.C., Nixon B., Dacheux J.L., Niwa H., Sekita Y.,
RA   Huang X., Stark A., Kheradpour P., Kellis M., Flicek P., Chen Y.,
RA   Webber C., Hardison R., Nelson J., Hallsworth-Pepin K., Delehaunty K.,
RA   Markovic C., Minx P., Feng Y., Kremitzki C., Mitreva M., Glasscock J.,
RA   Wylie T., Wohldmann P., Thiru P., Nhan M.N., Pohl C.S., Smith S.M.,
RA   Hou S., Nefedov M., de Jong P.J., Renfree M.B., Mardis E.R.,
RA   Wilson R.K.;
RT   "Genome analysis of the platypus reveals unique signatures of
RT   evolution.";
RL   Nature 453:175-183(2008).
RN   [2] {ECO:0000313|Ensembl:ENSOANP00000017850}
RP   IDENTIFICATION.
RC   STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000017850};
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   Ensembl; ENSOANT00000017853; ENSOANP00000017850; ENSOANG00000011265.
DR   GeneTree; ENSGT00940000157078; -.
DR   Proteomes; UP000002279; Unplaced.
DR   Bgee; ENSOANG00000011265; Expressed in 7 organ(s), highest expression level in adult mammalian kidney.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0070679; F:inositol 1,4,5 trisphosphate binding; IEA:InterPro.
DR   GO; GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; IEA:InterPro.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR000493; InsP3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   PRINTS; PR00779; INSP3RECEPTR.
DR   SMART; SM00472; MIR; 2.
DR   SUPFAM; SSF100909; SSF100909; 2.
DR   SUPFAM; SSF82109; SSF82109; 1.
DR   PROSITE; PS50919; MIR; 2.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002279};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002279};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2172   2194       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2214   2237       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2295   2320       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2341   2363       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2450   2473       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      213    269       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      353    412       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   COILED     1570   1590       {ECO:0000256|SAM:Coils}.
FT   COILED     2581   2608       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   2623 AA;  297760 MW;  DB9AF6DBA51F8DD1 CRC64;
     LVDDRCVVEP AAGDLDNPPK KFRDCLFKVC PMNRYSAQKQ YWKAKQTKQD KDKIADVVLL
     QKLQVSETLP GHSPPALFMV FDECLLCAGH YTKQKGSYKL ISLLSDLPAS SLAPLRSILH
     SAARLIFLQK QSGHVTPLLK QLQWLAINLR SDKNSALDAS RLCLTLPLSN SQTAQAWESE
     DLDFNPCSAS VNSVNGNTSW KINLFMQFRD HLEEVLKGGD VVRLFHAEQE KFLTCDEYKS
     KLQVFLRTTL RQSATSATSS NALWEVEVVH HDPCRGGAGH WNGLYRFKHL ATGNYLAAGV
     TPNTHNPPLR PGSPGSLRVL LDTSLYLGTH LPLCGGADTL AFILASSSSP GPRPPVPFGR
     RNSYVRLRHL CTNTWIQSTN VPIDIEEERP IRLMLGSCQA KEDKEDFAIV CVCGKIRDLD
     FANDASSMLA SAVDKLNAGF ISQNDRRFVI QLLEDLVFFV SDVPNNGQNV LDVAVPKPNR
     ERQKLMREQN ILKQIFGILK APFKDKGGEG PLVRLEELSD QKNAPYQYMF RLCYRVLRHS
     QEDYRKNQEH IAKQFGMMQS QIGYDILAED TITALLHNNR KLLEKHITKT EVETFVSLVR
     KNREPRFLDY LSDLCVSNHI AIPVTQELIC KCVLDPKNSD ILIKTELRPV KEMSQAHEYL
     SIEYSEEEVW LTWTDRNNEQ HEKSVRQLAQ EARAGNAHDE NVLSYYRYQL KLFARMCLDR
     QYLAIHEISK QLGVELIFLC LADEVLPFDL RASFCHLMLH VHVDRDPQEL VTPVKFARLW
     TEIPTAITIK DYDSNLNDSR DDKKNKFAST MEFVEDYLTG VVSEPAPFAN QEKNKLTFEV
     VSLAHNLIYF GFYSFSELLR LTRTLLGIID CVQNPQALLQ AEYNDDNGKD VRRSIQGVGQ
     MVSTMVLSRK PSLFGGTGLS VAGSPESLER GCSIDSENIV VMETKLKILE ILQFILNVRL
     DYRISYLLSV FKKEFVEEGI WGNPGDDQES SGCCTLCLPS SAAAMNLERI GEQAEAMFGI
     GRTSSMLEVD DEGGRMFLRV LIHLTMHDYA PLVSGALQLL FKHFSQRQEV MHTFKQVQLL
     ISAQDVENYK VIKSELDRLR TMVEKSELWV DKKSSHKGDE VGEGAKKEKK ERPNEEALPP
     TGERSSENYQ IVKGILERLN KLCGVGEQMR KKQQRLLKNM DAHKVMLDLL QVPYEKGDAK
     MQEILRSTHQ FLQKFCAGNP GNQALLHKHL SLFLTPGLLE AETMQHIFLN NYQLCAEIGE
     PVLQHFVHLL ATHGRHVQYL DFLHTVIKAE GKYVKKCQDA IMTELTNAGD DVVVFYNDKA
     SLAHMLEMMA AARDGVEENS PLMYHISLVD LLAACAEGKN VYTEIKCTSL LPLEDVVSVV
     THEDCITEVK IAYVNFVNHC YVDTEVEMKE IYTSNHIWTL FENFTLDMAR VCKKREKRIA
     DPTLEKYVLT VVLDTITAFF SSPFSENSTS LQTHQTIVVQ LLQSTMRLLE CPWLQQQHKG
     SVETCIRTLA MVAKSRAIAL PMDLDSHVSS LLNSSASCAV QRNAASYKTA TRTFPRVSTP
     ANQWDYKNII EKLQDIINTL EERLQPLVEA ELSVLVDVLH RPELLFLEGT DAYQRCESGG
     FLSKLIQHSK DLMESEEKLC IKVLRTLQQM LVKKSQYGDR GNTLRKMLLN NYLQNRKSSS
     KGEIPDPSGS GQDQDWALVA ATQCRLDKEG ATKLVSDLIM STKNEKIFQE SIGLAIRLLD
     GGNTEIQKSF YNLMMSDKKS ERFFKVLHER MKRAQQENKS TVSVNMSDLG SQAREGRDPG
     DPGEQAHKVL CTREVLSTCH RLCPRWGPPG PDCPPASRRG PGRGLRPPAL QPPLLPLQNF
     LRCQNNKTNY NLVCETLQFL DIMCGSTTGG LGLLGLYINE DNVALILQTL ETLTEYCQGP
     CHENQSCIVT HESNGIDIIT ALILNDISPL CKYRMDLVLQ LKDNASKLLL ALMESRHDGE
     NAERILISLR PQELVDVIKK AYLQEEECEN SEVSPREVGH NIYILALQLS RHNKTLQHLL
     KPVKRIQEEE EEGISSMVGV RDRDPGPHVP FPEGLRPQAL LLAGLESEPE MAEGGRGGRG
     QGQINQSITG IYWALNNNDD ISSIDCSPPA EQDEQGSKVS VFFDQSSFLH NEMEWQRKMR
     SMPLIYWFSR RMTLWGSISF NLAVFINIII AFFYPYVEGA STEGRVKDDT DELYIALILF
     SCHCFYEMFF PLTPLFLSVR LPRLDCKPTP ILPVLRVLPP QLTNKIVFVV SFVGNRGTFI
     RGYKAMVMDM EFLYHVGYIL TSVLGIFAHE LFYSILLFDL IYREETLFNV IKSVTRNGRS
     ILLTALLALI LVYLFSIVGF LFLKDDFILE VDRLPDNKSK GLHPLLWPYP SRFQSVIGSE
     RVNVWSGATQ PDSQEGDPGV LAPSPALCLR RLSSPALQES LFPARVIYDL LFFFIVIIIV
     LNLIFGVIID TFADLRSEKQ KKEEILKTTC FICGLERDKF DNKTVSFEEH IKFEHNMWNY
     LYFIVLVRVK NKTDYTGPES YVAQMIKNKN LDWFPRMRAM SLVSNEGEGE QNEIRSLQDK
     LNSTMKLVSH LTSQLNELKE QMTEQRKRRQ RMGFVDVQNC MSR
//
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