ID F7DRF2_CALJA Unreviewed; 451 AA.
AC F7DRF2;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 3.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=TEA domain transcription factor 2 {ECO:0000313|Ensembl:ENSCJAP00000000180.3};
GN Name=TEAD2 {ECO:0000313|Ensembl:ENSCJAP00000000180.3};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000000180.3, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000000180.3}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000000180.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR002603}.
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DR AlphaFoldDB; F7DRF2; -.
DR STRING; 9483.ENSCJAP00000000180; -.
DR Ensembl; ENSCJAT00000000191.3; ENSCJAP00000000180.3; ENSCJAG00000000104.4.
DR eggNOG; KOG3841; Eukaryota.
DR GeneTree; ENSGT00950000182956; -.
DR HOGENOM; CLU_012515_0_1_1; -.
DR InParanoid; F7DRF2; -.
DR TreeFam; TF313443; -.
DR Proteomes; UP000008225; Chromosome 22.
DR Bgee; ENSCJAG00000000104; Expressed in ovary and 6 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0035329; P:hippo signaling; IEA:InterPro.
DR Gene3D; 2.70.50.80; -; 1.
DR Gene3D; 6.10.20.40; TEA/ATTS domain; 1.
DR InterPro; IPR000818; TEA/ATTS_dom.
DR InterPro; IPR038096; TEA/ATTS_sf.
DR InterPro; IPR016361; TEF_metazoa.
DR InterPro; IPR041086; YBD.
DR PANTHER; PTHR11834; TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED; 1.
DR PANTHER; PTHR11834:SF5; TRANSCRIPTIONAL ENHANCER FACTOR TEF-4; 1.
DR Pfam; PF01285; TEA; 1.
DR Pfam; PF17725; YBD; 1.
DR PIRSF; PIRSF002603; TEF; 1.
DR PRINTS; PR00065; TEADOMAIN.
DR SMART; SM00426; TEA; 1.
DR PROSITE; PS00554; TEA_1; 1.
DR PROSITE; PS51088; TEA_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PIRNR:PIRNR002603};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR002603};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|PIRNR:PIRNR002603};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|PIRNR:PIRNR002603}.
FT DOMAIN 38..114
FT /note="TEA"
FT /evidence="ECO:0000259|PROSITE:PS51088"
FT DNA_BIND 38..114
FT /note="TEA"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00505"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 186..219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 198..219
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 451 AA; 49627 MW; A958DCEEEEDCDC4A CRC64;
MGEPRAGAPL DDGSGWTGSE EGSEEGTGGS EGAGGDGGPD AEGVWSPDIE QSFQEALAIY
PPCGRRKIIL SDEGKMYGRN ELIARYIKLR TGKTRTRKQV SSHIQVLARR KSREIQSKLK
DQVSKDKAFQ TMATMSSAQL ISAPSLQAKL GPTGPQVVEA SELFQFWSGG SGPPWNVPDV
KPFSQTPFSL SLTPPSTDLP GYEPPQALSP LPPPAPSPPA WQARALGTAR LQLVEFSAFV
EPPDAVDSYQ RHLFVHISQH CPSPGAPPLE SVDVRQIYDK FPEKKGGLRE LYDRGPPHAF
FLVKFWADLN WGPSGEEAGA GGSSSSSGGF YGVSSQYESL EHMTLTCSSK VCSFGKQVVE
KVETERAQLE DGRFVYRLLR SPMCEYLVNF LHKLRQLPER YMMNSVLENF TILQVVTNRD
TQELLLCTAY VFEVSTSERG AQHHIYRLVR D
//
