ID F7DZ13_CALJA Unreviewed; 482 AA.
AC F7DZ13;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Interferon-induced protein with tetratricopeptide repeats 5 {ECO:0000313|EMBL:JAB14729.1, ECO:0000313|Ensembl:ENSCJAP00000020664.2};
GN Name=IFIT5 {ECO:0000313|EMBL:JAB14729.1,
GN ECO:0000313|Ensembl:ENSCJAP00000020664.2};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000020664.2, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000020664.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:JAB14729.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Cerebellum {ECO:0000313|EMBL:JAB46759.1}, Cerebral cortex
RC {ECO:0000313|EMBL:JAB23771.1}, and Hippocampus
RC {ECO:0000313|EMBL:JAB14729.1};
RX PubMed=25243066; DOI=10.1186/2047-217X-3-14;
RA Maudhoo M.D., Ren D., Gradnigo J.S., Gibbs R.M., Lubker A.C.,
RA Moriyama E.N., French J.A., Norgren R.B.Jr.;
RT "De novo assembly of the common marmoset transcriptome from NextGen mRNA
RT sequences.";
RL Gigascience 3:14-14(2014).
RN [3] {ECO:0000313|Ensembl:ENSCJAP00000020664.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the IFIT family.
CC {ECO:0000256|ARBA:ARBA00038336}.
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DR EMBL; GAMS01008407; JAB14729.1; -; mRNA.
DR EMBL; GAMR01010161; JAB23771.1; -; mRNA.
DR EMBL; GAMP01005996; JAB46759.1; -; mRNA.
DR RefSeq; XP_002756433.1; XM_002756387.4.
DR STRING; 9483.ENSCJAP00000020664; -.
DR Ensembl; ENSCJAT00000021840.4; ENSCJAP00000020664.2; ENSCJAG00000011216.4.
DR GeneID; 100407481; -.
DR KEGG; cjc:100407481; -.
DR CTD; 24138; -.
DR eggNOG; KOG1124; Eukaryota.
DR GeneTree; ENSGT00950000182946; -.
DR HOGENOM; CLU_043482_1_0_1; -.
DR OMA; VYCEEGW; -.
DR OrthoDB; 5401272at2759; -.
DR TreeFam; TF342671; -.
DR Proteomes; UP000008225; Chromosome 12.
DR Bgee; ENSCJAG00000011216; Expressed in liver and 6 other cell types or tissues.
DR GO; GO:0015629; C:actin cytoskeleton; IEA:Ensembl.
DR GO; GO:0045177; C:apical part of cell; IEA:Ensembl.
DR GO; GO:0008385; C:IkappaB kinase complex; IEA:Ensembl.
DR GO; GO:0032587; C:ruffle membrane; IEA:Ensembl.
DR GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR GO; GO:0008266; F:poly(U) RNA binding; IEA:Ensembl.
DR GO; GO:0000339; F:RNA cap binding; IEA:Ensembl.
DR GO; GO:0000049; F:tRNA binding; IEA:Ensembl.
DR GO; GO:0051607; P:defense response to virus; IEA:Ensembl.
DR GO; GO:0045071; P:negative regulation of viral genome replication; IEA:Ensembl.
DR GO; GO:0043123; P:positive regulation of canonical NF-kappaB signal transduction; IEA:Ensembl.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR013105; TPR_2.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR10271; INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS; 1.
DR PANTHER; PTHR10271:SF28; INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS 5; 1.
DR Pfam; PF13424; TPR_12; 1.
DR Pfam; PF07719; TPR_2; 1.
DR Pfam; PF13181; TPR_8; 2.
DR SMART; SM00028; TPR; 5.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 3.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 249..282
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 338..371
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 435..468
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT COILED 60..94
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 482 AA; 55733 MW; 048DF0652F30EE25 CRC64;
MSEIPKDTLK TILLELECHF TWNLLKEDID LFEVEDTIGQ QLEFLTTKSR LALYNLLAYV
KHLKGQNKDA LECLEQAEEI IQREHSDKEE VRSLVTWGNY AWVYYHMDQL EEAQKYTGKI
GNVCKKLSSP SVYKLVCPEI DCEKGWALLK FGGKYYQKAK AAFEKALEVE PDNPEFNIGY
AITVYRLDDS DREGSVKSFS LGPLRKAVTL NPDDSYIKVF LALKLQDVHA EAEGEKYIEE
ILDQISSQPY VLRYAAKFYR RKNSWDKALE LLKKALEVTP TSSFLHHQMG LCYRAQMIQI
KKATRNRPKG KDKLKVDELI TSAIFHFKAA MEQDSMFAFA YTDLANMYAE GGLYSNAEDI
FQKALRLENI TDDHKHQIHY HYGRFQEFHR KSENTAIHHY LEALKVKDRS PLRTKLTSAL
KKLATKRLCH NALDVQSLSA LGFVYKLEGE KRQAAEYYEK AQKIDPENAE FLTALCELQL
SI
//
