ID F7E828_MONDO Unreviewed; 836 AA.
AC F7E828;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 2.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Striatin interacting protein 2 {ECO:0000313|Ensembl:ENSMODP00000018332.3};
GN Name=STRIP2 {ECO:0000313|Ensembl:ENSMODP00000018332.3};
OS Monodelphis domestica (Gray short-tailed opossum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Didelphimorphia; Didelphidae; Monodelphis.
OX NCBI_TaxID=13616 {ECO:0000313|Ensembl:ENSMODP00000018332.3, ECO:0000313|Proteomes:UP000002280};
RN [1] {ECO:0000313|Ensembl:ENSMODP00000018332.3, ECO:0000313|Proteomes:UP000002280}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=17495919; DOI=10.1038/nature05805;
RA Mikkelsen T.S., Wakefield M.J., Aken B., Amemiya C.T., Chang J.L., Duke S.,
RA Garber M., Gentles A.J., Goodstadt L., Heger A., Jurka J., Kamal M.,
RA Mauceli E., Searle S.M., Sharpe T., Baker M.L., Batzer M.A., Benos P.V.,
RA Belov K., Clamp M., Cook A., Cuff J., Das R., Davidow L., Deakin J.E.,
RA Fazzari M.J., Glass J.L., Grabherr M., Greally J.M., Gu W., Hore T.A.,
RA Huttley G.A., Kleber M., Jirtle R.L., Koina E., Lee J.T., Mahony S.,
RA Marra M.A., Miller R.D., Nicholls R.D., Oda M., Papenfuss A.T., Parra Z.E.,
RA Pollock D.D., Ray D.A., Schein J.E., Speed T.P., Thompson K.,
RA VandeBerg J.L., Wade C.M., Walker J.A., Waters P.D., Webber C.,
RA Weidman J.R., Xie X., Zody M.C., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Bloom T., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., MacCallum I., Graves J.A., Ponting C.P., Breen M.,
RA Samollow P.B., Lander E.S., Lindblad-Toh K.;
RT "Genome of the marsupial Monodelphis domestica reveals innovation in non-
RT coding sequences.";
RL Nature 447:167-177(2007).
RN [2] {ECO:0000313|Ensembl:ENSMODP00000018332.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the STRIP family.
CC {ECO:0000256|ARBA:ARBA00007062}.
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DR RefSeq; XP_007504362.1; XM_007504300.2.
DR AlphaFoldDB; F7E828; -.
DR STRING; 13616.ENSMODP00000018332; -.
DR Ensembl; ENSMODT00000018665.4; ENSMODP00000018332.3; ENSMODG00000014664.4.
DR GeneID; 100019850; -.
DR CTD; 57464; -.
DR eggNOG; KOG3680; Eukaryota.
DR GeneTree; ENSGT00400000022095; -.
DR HOGENOM; CLU_011008_1_0_1; -.
DR InParanoid; F7E828; -.
DR OMA; KMTRAMR; -.
DR OrthoDB; 5491701at2759; -.
DR TreeFam; TF314205; -.
DR Proteomes; UP000002280; Chromosome 8.
DR Bgee; ENSMODG00000014664; Expressed in adult mammalian kidney and 14 other cell types or tissues.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR GO; GO:0007010; P:cytoskeleton organization; IBA:GO_Central.
DR GO; GO:0008360; P:regulation of cell shape; IEA:Ensembl.
DR InterPro; IPR040185; Far11/STRP.
DR InterPro; IPR021819; Far11/STRP_C.
DR InterPro; IPR012486; Far11/STRP_N.
DR PANTHER; PTHR13239; PROTEIN REQUIRED FOR HYPHAL ANASTOMOSIS HAM-2; 1.
DR PANTHER; PTHR13239:SF6; STRIATIN-INTERACTING PROTEIN 2; 1.
DR Pfam; PF11882; DUF3402; 2.
DR Pfam; PF07923; N1221; 1.
DR SMART; SM01293; DUF3402; 1.
DR SMART; SM01292; N1221; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002280}.
FT DOMAIN 54..379
FT /note="Far11/STRP N-terminal"
FT /evidence="ECO:0000259|SMART:SM01292"
FT DOMAIN 458..814
FT /note="Far11/STRP C-terminal"
FT /evidence="ECO:0000259|SMART:SM01293"
FT REGION 1..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 327..350
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 364..387
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..53
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 329..343
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 373..387
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 836 AA; 95527 MW; 377EA97AA1F01B38 CRC64;
MEDPGGGDGG QAAGSPPGNG SCGGGGGSKG KQASPKGREM FKNQRRESEG SVDCPNLEFE
YGDADEHGAE LSELYSYTEN PEFIINRHCF EEDFRTQVQG RGWLELEEAS QKAYIMRLLD
RLEVVNREQR LKVARAILYL AQGTFGECDT EADVLHWSRY NSFLLYQMGT FTAFLELLHM
ETDNSQACSS ALRKPAISLA DSTELRVLLS VMYLMVENIR LERETDPSGW RATRETFRTE
LTFPVRSEEP FALLLFSMIT KFCSGLAPHF PMKKVLLLLW KVVLFTLGGF EVLQALKIQK
RAELGLPPLA EDSIQVVRSM RAASPPSYTL DLGESQMAPQ SSKQRGRRGR KLLTKQDSLD
IYNERDLFKN EEPPPEEEEE AGEGESTLDG ELDLLERGPL VPPLLSQTPT TERVTFPKGL
PWAPKVRQKD IEHFLEISRN KFIGFTLGQD TDTLVGLPRP IHESVKTLKQ HKYVSISDVQ
IKNEEELEKC PMSLGEEEVQ ETPCEILYQA MLYNLPQYMI ALLKILLAAA PTSKAKTDSI
NILADVLPEE MPITVLQSMK LGIDVNRHKE IIVKSISAVL LLLLKHFKLN HIYQFEYVSQ
HLVFANCIPL ILKFFNQNIL SYITAKNSIS VLDYPSCTVH DLPDLTAESL EAGDNNQFCW
RNLFSCINLL RLLNKLTKWK HSRTMMLVVF KSAPILKRAL KVKQAMLQLY VLKLLKIQTK
YLGRQWRKSN MKTMSAIYQK VRHRMNDDWA YGNDIDARPW DFQAEECTLR ANIEAFNSRR
YDRPQDSEFA PVDNCLQSVL GQKLELPEDF YYSYELWLER EVFSQPICWE ELLQSH
//
