ID F7ED00_CALJA Unreviewed; 531 AA.
AC F7ED00;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 3.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Bridging integrator 2 {ECO:0000313|Ensembl:ENSCJAP00000032622.4};
GN Name=BIN2 {ECO:0000313|Ensembl:ENSCJAP00000032622.4};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000032622.4, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000032622.4}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000032622.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F7ED00; -.
DR Ensembl; ENSCJAT00000034478.4; ENSCJAP00000032622.4; ENSCJAG00000017685.5.
DR eggNOG; KOG3771; Eukaryota.
DR GeneTree; ENSGT00950000182882; -.
DR HOGENOM; CLU_017859_7_0_1; -.
DR TreeFam; TF313542; -.
DR Proteomes; UP000008225; Chromosome 9.
DR Bgee; ENSCJAG00000017685; Expressed in liver and 6 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 2.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR003005; Amphiphysin.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR048886; Bin2_C.
DR PANTHER; PTHR46514; AMPHIPHYSIN; 1.
DR PANTHER; PTHR46514:SF1; BRIDGING INTEGRATOR 2; 1.
DR Pfam; PF03114; BAR; 2.
DR Pfam; PF21532; Bin2_C; 1.
DR PRINTS; PR01251; AMPHIPHYSIN.
DR SMART; SM00721; BAR; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR PROSITE; PS51021; BAR; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225}.
FT DOMAIN 1..212
FT /note="BAR"
FT /evidence="ECO:0000259|PROSITE:PS51021"
FT REGION 231..250
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 283..531
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 124..158
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 283..299
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 315..377
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 380..401
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 402..432
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 456..476
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 478..494
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 495..509
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 531 AA; 57953 MW; 9C7AFA8532FD40C9 CRC64;
MAEGKAGGAA GLFAKQVQKK FSRAQEKMLQ KLGKTVETKD ERFEQSANNF YQQQAEGHKL
YKDLKNFLSA VKVMHESSKR VSETLQEIYS SEWDGHQELK AIVGERIAKR GRKLVDYDSA
RHHLEAVQNA KKKDEAKTAR AEEEFNKAQT VFEDLNQELL EELPILYNSR IGCYVTIFQN
ISNLRDVFYR EMSKLNHNLY EVMSKLEKQH SNKVFVVKGL SSGSRRSLVI SPPVRTSTAS
SPLNSPTSCS TLSLKSENEF VSATEDLAPV AAQGEGNSEI KELLEDEEIE KEGSEASSSE
EEEPLPACNG PAQAQPSLAI ESAKSQEEVL PNSPTPSPGR ALSSSGQPSS SATEVILRTR
TASEGSEQPN KRASIQRTSA PPCRPPPPRA TPSPRPSSGN IPSSPPASGE CSPTSSRASL
ESGTSSPRTS LEVSPNPEPP EKPVRTLEAK ENENIQNPEE VCTSPALMTS QIASEPGEAK
TIEDKEEDNK LVSADSSEGQ DQLEVSMVPD KSNLTAPERQ EEVSTSENAQ L
//
