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Database: UniProt
Entry: F7EG17_MONDO
LinkDB: F7EG17_MONDO
Original site: F7EG17_MONDO 
ID   F7EG17_MONDO            Unreviewed;      2773 AA.
AC   F7EG17;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   11-DEC-2019, sequence version 2.
DT   07-OCT-2020, entry version 51.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMODP00000004023};
OS   Monodelphis domestica (Gray short-tailed opossum).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Metatheria; Didelphimorphia; Didelphidae; Monodelphis.
OX   NCBI_TaxID=13616 {ECO:0000313|Ensembl:ENSMODP00000004023, ECO:0000313|Proteomes:UP000002280};
RN   [1] {ECO:0000313|Ensembl:ENSMODP00000004023, ECO:0000313|Proteomes:UP000002280}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17495919; DOI=10.1038/nature05805;
RA   Mikkelsen T.S., Wakefield M.J., Aken B., Amemiya C.T., Chang J.L., Duke S.,
RA   Garber M., Gentles A.J., Goodstadt L., Heger A., Jurka J., Kamal M.,
RA   Mauceli E., Searle S.M., Sharpe T., Baker M.L., Batzer M.A., Benos P.V.,
RA   Belov K., Clamp M., Cook A., Cuff J., Das R., Davidow L., Deakin J.E.,
RA   Fazzari M.J., Glass J.L., Grabherr M., Greally J.M., Gu W., Hore T.A.,
RA   Huttley G.A., Kleber M., Jirtle R.L., Koina E., Lee J.T., Mahony S.,
RA   Marra M.A., Miller R.D., Nicholls R.D., Oda M., Papenfuss A.T., Parra Z.E.,
RA   Pollock D.D., Ray D.A., Schein J.E., Speed T.P., Thompson K.,
RA   VandeBerg J.L., Wade C.M., Walker J.A., Waters P.D., Webber C.,
RA   Weidman J.R., Xie X., Zody M.C., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA   Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA   Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA   Bayul T., Berlin A., Bessette D., Bloom T., Bloom T., Boguslavskiy L.,
RA   Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA   Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA   D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA   Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA   Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA   Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA   Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA   Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA   Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA   Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA   Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA   Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA   McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA   Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA   Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA   Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA   Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA   Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA   Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA   Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA   Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA   Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA   Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA   Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA   Chin C., Gnerre S., MacCallum I., Graves J.A., Ponting C.P., Breen M.,
RA   Samollow P.B., Lander E.S., Lindblad-Toh K.;
RT   "Genome of the marsupial Monodelphis domestica reveals innovation in non-
RT   coding sequences.";
RL   Nature 447:167-177(2007).
RN   [2] {ECO:0000313|Ensembl:ENSMODP00000004023}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   STRING; 13616.ENSMODP00000004023; -.
DR   Ensembl; ENSMODT00000004109; ENSMODP00000004023; ENSMODG00000003291.
DR   eggNOG; ENOG502QVMD; Eukaryota.
DR   GeneTree; ENSGT00730000111187; -.
DR   HOGENOM; CLU_000551_0_0_1; -.
DR   InParanoid; F7EG17; -.
DR   TreeFam; TF101133; -.
DR   Proteomes; UP000002280; Chromosome 2.
DR   Bgee; ENSMODG00000003291; Expressed in hindlimb bud and 21 other tissues.
DR   GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR   GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 2.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 2.
DR   Pfam; PF10481; CENP-F_N; 2.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002280}.
FT   DOMAIN          1..122
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          133..251
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          1978..2086
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2192..2271
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2673..2717
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          156..211
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2598..2649
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2710..2733
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          13..76
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          98..125
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          217..279
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          287..325
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          337..403
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          411..494
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          515..584
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          606..686
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          796..851
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          919..946
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          981..1001
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1017..1037
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1109..1143
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1184..1225
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1230..1257
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1454..1492
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1497..1551
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1691..1711
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1719..1746
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1772..1841
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1870..1939
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1954..2188
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2192..2286
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2294..2349
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2360..2428
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2431..2465
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2481..2529
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2536..2563
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        156..181
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2598..2624
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   2773 AA;  321164 MW;  885A94D3B3243D26 CRC64;
     MSWALEEWKE GLSTRALQKI QELEGQLDKL KKERQQRQFQ LESLEAALQK QKQKVAEDQK
     NEGASLKREN QSLMETCDNL VKMKQKISHE LQVKESQVNF QEGQLNSSKK QIEKLEQELK
     RFFKVFSHFI IFSQKASKPV PPSTLSHREI ARHQASSSVF SWQQEKTPTH HSASAQETPH
     KRGFTALQIP WEQETPPNRK SSWQTERKDT SYSFHENQSN LNLLDQLKAQ NQELKCKVNE
     LDHQLQAQEH DIKGYMNKLQ ETQLQLEKTK LELTEKDKVL NKSGDEVMRL TSQLDRVTAK
     CTKLEQKLKK MSEDLNCQRQ NAESTRCSLE QKIKDKDKDY QEELSHQQRT LQMLDQENTQ
     IKTKLNQELQ QARSTQNILQ AELDKVIVMK QQLEKNSDEF KQKLCRTEQA LQTSQTKEND
     LRRSMEEMMQ EKQLLSHQLD KKSREVNQLE EELKKMKHCL KQSQNLAEEM KDKNATQEGV
     LKALQEKINQ QEKSSVLELA VADLEKQRDC SQDLLKKREH HIEQLNDKLL NTQRELEGLL
     NTLGLKEKEC EELKKETILF SQWKNEKEQL LNQLLLEKEG LQSTISNLEI CLKTQHVKSH
     DVNESFKIME TENEKLGLEI KNLQNAIEGK NIELEAQKQA YEELQQKAEY SDQKYKKEVE
     NLSLKIVQLT TEVEHLKQKL QLLSSEIIGK DQRYEELHIQ YEKISSLVKS ENSSQMMNED
     YCGRDLLILE QPVLNNSISN ILEIQGSLPL EQGDKRTKLH SEDQSMENVA KLQHKVSSSE
     CNIHIINFVT ETNLFIDETL IALENKDKQL QKLSEQLEYG EAEIKDLKTK NQLLEESVKK
     LSSEIKEINS ILLQNKKEIE ELIHENGNLK EINAILNIEK MNLIQKNVSF SNCFIEREKT
     ISELSDRSKE EELLLLKRCE EAEKGLEILK EKYKLMEEKN IELECILKEH TITSLCGKGN
     NELKELEEAF AREHKDYMSK LALAEEKNEK LIFEMETMQC RLRAEVVAIQ NSSKIEADGL
     RQEISNFKDE QNKMQEQHHF LLQENDRLMK LVKGKNVQMN ELVLTSSPAS EQISESVNEL
     DNLEVTQIEM LHLNLEAKDS SLNTHNAQVI SLEQVIEHME LRLKESEKEK EVLQQELEMI
     KKELKIRDSS DQSFETSNYE HCKREMDEKY ISVLHELSTS QNDNAQLMTS LQTTVNKLNE
     LEKMCEILQT EKLELTSELN DSKSECILAT TKMAEKVEKL VNEVKTLNNK NSDLSGELIK
     ENGKDEFREQ FDQPKSICLE LIEGRIEGGN DYEHLKLSNK EVQMHFIELQ EKFSSLQIEH
     RILHEQHCHM SSKLSELCSY TDTLKAENSV LSVNLKNIQT DLMKQLTPGK EEIVAEEGES
     LSSCMNEIAN LTSFVESSFY KDLFEETREI PSLNSLEENL LDNQSSANID ESPCSSLDAG
     FMTKNTRSGP NLNIEEFETL CQSYQISIKN LEDKYENQKI MKDKEIQELK ELICSERNEL
     EFLRKQYLSE IEQWQEKLAN VTMEMESKLA AEKKQSEYLS LQLEVAGLQL QDLELSSRSF
     LIAEGEDVSM LCLFSPSICC SNEKSYVNEL TPCNLQDTFN SECEEIAEIE GISSVAVYSR
     EVNLENEHRR SSDKTHSECI PESSFSSNDT LAAMDFLENQ VLIQNLQFKV KETSNENLKL
     IHGIEERDKK VDRLLSEIKE LDYKVDLQKA ELTAKICMCS ELEKVIQELQ KEKSDLNEKL
     RFLSYDNQKL LQRVKSEKTS IENHAFSLEA DLESLQTKNL CLEKDNENKQ KVISNLEEQL
     SLIISERNQL NGELDILLKS KLKMEEICDE LKERVKVLES SQRKSLQHIQ VVESEVRDKT
     QLLQTMSSDV NQLLKDKDYL QEQLQNLEKD AQMLSLIKDG LKNEISQLTD EKELFLRQSE
     NQQAKLNDVE AENVNLSKAL EGSLIEKGEI AARLNSTQEE VHQLKNGIEK LKVRIEADEK
     KKHHVLEKLK ESERKADSFK DKIEALEREL LMSEENQEAI ILDAENAKSE LETLKTQMEE
     LTKGLKRNLQ CLETELVSLR SEKDNMSKEL QEKQSQVCEL EELTRSLNSL ESEVASLRKE
     KENILKDLQE KQAQNCELEE VTRNLQCLET ELVSLRSEKD HMSKVLEEKQ SQVCELEELT
     KKKLSRNLKS LETEFASLTS EKENMLKQLC ESEKLTKNLK CLETELVSLS SEKQNVLKEL
     QEKQAQVEEL KMLNVSFESL LEKKEEEKRK LKEESQHTTE LLQKQLNDLN EKIDSFQEEH
     NIHKASEQDL NCQVDCLKHE KIHLLQQLEE TKNNNAMLKS SVNDFIQEIE NNKQKLEKTT
     EENGILQKQV QDLGKLTSML TQMEAEQQLW EKEKSQLEHL TVELQQKIQE LSKNETLYNS
     LEALQNSYAN LENELNLTKK ENSSLLEKVN YEKITNNEAL LQHEINEMMQ KMTVLQEEYN
     GEKNRFTDYI KIKEVENVKY VTQLKKENEN ARGKIQLLIK NCKQLENEKE ALQKEINGLE
     TLQENQKQSS TMGVNVEELM AEVKELKEAI EGKNKETDEY LDKYCNLLVS YEKMEKAKNM
     LESQVTLLNS LQGKIASQSS PMLSSDDSMH CSSQPVTENK TLASHGKVPS KRPRSRIAKE
     SDGDALPSTP ETFIKKIKKE VTPKGITYSL RGLENTQYEP EGLPEVVKKG FADIPTEKTS
     PYILRRTTMA TKTRTSPRLA AQKLSPPDLQ KKESKNLAET FKPAAGGSKS QMVNNYCVQG
     ALVHTIFSQL PKD
//
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