ID F7EJD9_CALJA Unreviewed; 377 AA.
AC F7EJD9;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Actin-binding Rho-activating protein {ECO:0000313|EMBL:JAB40706.1, ECO:0000313|Ensembl:ENSCJAP00000061999.1};
GN Name=ABRA {ECO:0000313|EMBL:JAB40706.1,
GN ECO:0000313|Ensembl:ENSCJAP00000061999.1};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|EMBL:JAB40706.1};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000061999.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:JAB40706.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Skeletal muscle {ECO:0000313|EMBL:JAB40706.1};
RX PubMed=25243066; DOI=10.1186/2047-217X-3-14;
RA Maudhoo M.D., Ren D., Gradnigo J.S., Gibbs R.M., Lubker A.C.,
RA Moriyama E.N., French J.A., Norgren R.B.Jr.;
RT "De novo assembly of the common marmoset transcriptome from NextGen mRNA
RT sequences.";
RL Gigascience 3:14-14(2014).
RN [3] {ECO:0000313|Ensembl:ENSCJAP00000061999.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GAMQ01001145; JAB40706.1; -; mRNA.
DR RefSeq; XP_002759351.1; XM_002759305.3.
DR STRING; 9483.ENSCJAP00000061999; -.
DR Ensembl; ENSCJAT00000078910.2; ENSCJAP00000061999.1; ENSCJAG00000040325.2.
DR GeneID; 100415185; -.
DR KEGG; cjc:100415185; -.
DR CTD; 137735; -.
DR eggNOG; KOG3376; Eukaryota.
DR GeneTree; ENSGT00390000015984; -.
DR HOGENOM; CLU_062244_0_0_1; -.
DR OMA; DEPKWRS; -.
DR OrthoDB; 4166202at2759; -.
DR TreeFam; TF328879; -.
DR Proteomes; UP000008225; Chromosome 16.
DR Bgee; ENSCJAG00000040325; Expressed in heart and 1 other cell type or tissue.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0035025; P:positive regulation of Rho protein signal transduction; IEA:InterPro.
DR Gene3D; 1.10.10.1540; Costar domain; 1.
DR InterPro; IPR026111; Abra.
DR InterPro; IPR027817; Costars_dom.
DR InterPro; IPR038095; Costars_sf.
DR PANTHER; PTHR22739:SF20; ACTIN-BINDING RHO-ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR22739; STRIATED MUSCLE ACTIVATOR OF RHO-DEPENDENT SIGNALING-RELATED; 1.
DR Pfam; PF14705; Costars; 1.
DR SMART; SM01283; Costars; 1.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000008225}.
FT DOMAIN 300..376
FT /note="Costars"
FT /evidence="ECO:0000259|SMART:SM01283"
FT REGION 36..126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 170..205
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..50
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 89..113
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..184
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 377 AA; 42810 MW; A38661C88C6AAE42 CRC64;
MAPGEKEREG PAKSALRKIR TATLVINLAR GWQQWANENS TRQAQEPSGW LPGGTQDPPQ
APKPITCPTP HQKARSVPKS PPRTPEGHGD GQSSEKAPEV SHIKKKEVTK TVVSKAYERG
GDVNHLSHRY ERDAGVPEPE NDIDRILHSH GSPTRRRKCA NLVSELTKGW RVMEQEEPTG
RSDSIDTEDS GYGGEAEERQ EQDGVQVAVA RIKRPLPSQV NRFTEKLNCK AQQKYSQVGN
LKGRWQQWAD EHIQSQKLNP FSEEFDYELA MSTRLHKGDE GYGRPKEGTK TAERAKRAEE
HIYREIMDMC FIIRTMARHR RDGKIQVTFG DLFDRYVRIS DKVVGILMRA RKHGLVDFAG
EMLWQGRDDH VVITLLE
//
