ID   F7EJS6_CALJA            Unreviewed;       393 AA.
AC   F7EJS6;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   25-MAY-2022, sequence version 4.
DT   27-MAR-2024, entry version 46.
DE   SubName: Full=Src homology 2 domain containing F {ECO:0000313|Ensembl:ENSCJAP00000003939.5};
GN   Name=SHF {ECO:0000313|Ensembl:ENSCJAP00000003939.5};
OS   Callithrix jacchus (White-tufted-ear marmoset).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Callitrichinae; Callithrix; Callithrix.
OX   NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000003939.5, ECO:0000313|Proteomes:UP000008225};
RN   [1] {ECO:0000313|Ensembl:ENSCJAP00000003939.5}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCJAP00000003939.5}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; F7EJS6; -.
DR   Ensembl; ENSCJAT00000004153.5; ENSCJAP00000003939.5; ENSCJAG00000002159.5.
DR   eggNOG; ENOG502QTRD; Eukaryota.
DR   GeneTree; ENSGT00940000159452; -.
DR   TreeFam; TF325799; -.
DR   Proteomes; UP000008225; Chromosome 10.
DR   Bgee; ENSCJAG00000002159; Expressed in cerebellum and 6 other cell types or tissues.
DR   CDD; cd10392; SH2_SHF; 1.
DR   Gene3D; 3.30.505.10; SH2 domain; 1.
DR   InterPro; IPR000980; SH2.
DR   InterPro; IPR036860; SH2_dom_sf.
DR   InterPro; IPR035044; SHF_SH2.
DR   PANTHER; PTHR15127; HEAVYWEIGHT, ISOFORM A; 1.
DR   PANTHER; PTHR15127:SF28; SH2 DOMAIN-CONTAINING ADAPTER PROTEIN F; 1.
DR   Pfam; PF00017; SH2; 1.
DR   PRINTS; PR00401; SH2DOMAIN.
DR   SMART; SM00252; SH2; 1.
DR   SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
DR   SUPFAM; SSF55550; SH2 domain; 1.
DR   PROSITE; PS50001; SH2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW   SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT   DOMAIN          293..388
FT                   /note="SH2"
FT                   /evidence="ECO:0000259|PROSITE:PS50001"
FT   REGION          1..178
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          195..278
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        29..61
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        155..178
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   393 AA;  43021 MW;  69257C6A93F910D0 CRC64;
     MPRLQRERDF EDPYSGGSSG SAALAAPATS GPTPPPRHGS PPHRLIRVET PGPPAPPADE
     RISGPPSSGD RLAILEDYAD PFDVQETGED SAGASGAPEK VPENDGYMEP YEAQKMMAEI
     RGSKETAAQP LPLYDTPYEP EEDGATPEGE GAPWPRESRL PEDDERPPEE YDQPWEWKKE
     RISKAFAVDI KVIKDLPWPP PVGQLDSSPS LPDGDRDISD PASPLPEPSL EDSSAQFEGS
     EKSCLSPGRE EKGRLPPRLS AGNPKSAKPI SVEPSSPLGE WTDPALPLEN QVWYHGAISR
     TDAENLLRLC KEASYLVRNS ETSKNDFSLS LKSSQGFMHM KLSRTKEHKY VLGQNSPPFS
     SVPEIVHHYA SRKLPIKGAE HMSLLYPVAI RTL
//