ID F7EWH9_CALJA Unreviewed; 904 AA.
AC F7EWH9;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 4.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=DEAD/H-box helicase 11 {ECO:0000313|Ensembl:ENSCJAP00000012460.5};
GN Name=DDX11 {ECO:0000313|Ensembl:ENSCJAP00000012460.5};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000012460.5, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000012460.5}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000012460.5}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. DEAH subfamily.
CC DDX11/CHL1 sub-subfamily. {ECO:0000256|ARBA:ARBA00008435}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; F7EWH9; -.
DR Ensembl; ENSCJAT00000013134.5; ENSCJAP00000012460.5; ENSCJAG00000005153.6.
DR GeneTree; ENSGT00950000182970; -.
DR Proteomes; UP000008225; Chromosome 9.
DR Bgee; ENSCJAG00000005153; Expressed in ovary and 6 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR CDD; cd18788; SF2_C_XPD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR006555; ATP-dep_Helicase_C.
DR InterPro; IPR045028; DinG/Rad3-like.
DR InterPro; IPR014013; Helic_SF1/SF2_ATP-bd_DinG/Rad3.
DR InterPro; IPR006554; Helicase-like_DEXD_c2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010614; RAD3-like_helicase_DEAD.
DR InterPro; IPR013020; Rad3/Chl1-like.
DR NCBIfam; TIGR00604; rad3; 1.
DR PANTHER; PTHR11472:SF41; ATP-DEPENDENT DNA HELICASE DDX11-RELATED; 1.
DR PANTHER; PTHR11472; DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER; 1.
DR Pfam; PF06733; DEAD_2; 1.
DR Pfam; PF13307; Helicase_C_2; 1.
DR SMART; SM00488; DEXDc2; 1.
DR SMART; SM00491; HELICc2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51193; HELICASE_ATP_BIND_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225}.
FT DOMAIN 9..445
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51193"
FT REGION 289..312
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 130..177
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 904 AA; 101488 MW; 030A96734D7047FC CRC64;
MANETQKAGG IHFPFPFTPY SIQKDFMAEL YRVLDAGKIG IFESPTGTGK SLSLICGALS
WLRDFEQKKR EEEARLLETG TGPLRHEKDE SPCLSSSCEV AAGTPRPAGE PAWVTEFVQK
KEERDLVDRL KAEQARRRQR EERLQQLQHR AQLKYAAKRL RQEQEETENL LRLSREMLET
GPVAERLEQL ESGEEELVLA EYESDEEKKA VSRVDEDEDD LEEEHVTKVY YCSRTHSQLA
QFVHEVKKSP FGKDVRLVSL GSRQNLCVNE DVKSLGSVQL INDRCVDMQR SRHEKKKGAE
EEKPKRRRPE KQAACPFYNH EQMGLLRDEA LAEVKDIEQL LALGKEARAC PYYGSRLAIP
AAQLVVLPYQ MLLHAATRQA AGIRLQDQVV IIDEAHNLID TITGMHSVEV SGSQLCQAYS
QLLQYMERYS KRLKAKNLMY LKQILYLLEK FVAMLGGNIK QNPNTQSLSQ TGTELKTIND
FLFQSQIDNI NLFKVQRYCE KSMVSRKLFG FTERYGAVLS SREQPKLAGF QQFLQSLQPK
ATEAVPADES PATALRPASP LMHIEGFLAA LTTANQDGRV ILSRQGSLSQ SSLKFLLLNP
AVHFAQVVKE CRAVVIAGGT MQPVSDFRQQ LLACAGVEPE RVVEFSCGHV IPPDNILPLV
ICSGISSQPL EFTFQKRELP QMMDEAGRIL CNLCGVVPGG VVCFFPSYEY LRQVHTHWEK
GGLLDRLAAR KKIFQEPKST HQVEQVLLAY SRCIQGCGQE RGRVTGALLL SVVGGKMSEG
INFSDNLGRC VVMVGMPFPN IRSPELQEKM AYLDQTLPRA PGQAPPGKAL VENLCMKAVN
QSIGRAIRHQ RDFASIVLLD QRYARPPVLA KLPAWIQARV EVKAAFGPAI AAVQKFHREK
AASF
//
