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Database: UniProt
Entry: F7F2F2_CALJA
LinkDB: F7F2F2_CALJA
Original site: F7F2F2_CALJA 
ID   F7F2F2_CALJA            Unreviewed;      1141 AA.
AC   F7F2F2;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   27-JUL-2011, sequence version 1.
DT   08-MAY-2019, entry version 53.
DE   SubName: Full=Integrin alpha-7 isoform 1 {ECO:0000313|EMBL:JAB09391.1};
GN   Name=ITGA7 {ECO:0000313|EMBL:JAB09391.1,
GN   ECO:0000313|Ensembl:ENSCJAP00000015080};
OS   Callithrix jacchus (White-tufted-ear marmoset).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix.
OX   NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000015080, ECO:0000313|Proteomes:UP000008225};
RN   [1] {ECO:0000313|Ensembl:ENSCJAP00000015080, ECO:0000313|Proteomes:UP000008225}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCJAP00000015080}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
RN   [3] {ECO:0000313|EMBL:JAB09391.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Bladder {ECO:0000313|EMBL:JAB09391.1}, and Cerebellum
RC   {ECO:0000313|EMBL:JAB52592.1};
RX   PubMed=25243066; DOI=10.1186/2047-217X-3-14;
RA   Maudhoo M.D., Ren D., Gradnigo J.S., Gibbs R.M., Lubker A.C.,
RA   Moriyama E.N., French J.A., Norgren R.B.Jr.;
RT   "De novo assembly of the common marmoset transcriptome from NextGen
RT   mRNA sequences.";
RL   Gigascience 3:14-14(2014).
CC   -!- SUBUNIT: Heterodimer of an alpha and a beta subunit.
CC       {ECO:0000256|SAAS:SAAS01130326}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003762};
CC       Single-pass type I membrane protein
CC       {ECO:0000256|RuleBase:RU003762}.
CC   -!- SIMILARITY: Belongs to the integrin alpha chain family.
CC       {ECO:0000256|RuleBase:RU003762, ECO:0000256|SAAS:SAAS00534092}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|RuleBase:RU003762}.
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DR   EMBL; GAMT01002470; JAB09391.1; -; mRNA.
DR   EMBL; GAMP01000163; JAB52592.1; -; mRNA.
DR   RefSeq; XP_017831605.1; XM_017976116.1.
DR   Ensembl; ENSCJAT00000015916; ENSCJAP00000015080; ENSCJAG00000008045.
DR   GeneID; 100401654; -.
DR   KEGG; cjc:100401654; -.
DR   CTD; 3679; -.
DR   eggNOG; KOG3637; Eukaryota.
DR   eggNOG; ENOG410XPVZ; LUCA.
DR   GeneTree; ENSGT00940000159891; -.
DR   KO; K06583; -.
DR   OrthoDB; 743479at2759; -.
DR   Proteomes; UP000008225; Unplaced.
DR   GO; GO:0008305; C:integrin complex; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.130; -; 1.
DR   InterPro; IPR013517; FG-GAP.
DR   InterPro; IPR013519; Int_alpha_beta-p.
DR   InterPro; IPR000413; Integrin_alpha.
DR   InterPro; IPR013649; Integrin_alpha-2.
DR   InterPro; IPR018184; Integrin_alpha_C_CS.
DR   InterPro; IPR028994; Integrin_alpha_N.
DR   InterPro; IPR032695; Integrin_dom_sf.
DR   Pfam; PF01839; FG-GAP; 2.
DR   Pfam; PF08441; Integrin_alpha2; 1.
DR   PRINTS; PR01185; INTEGRINA.
DR   SMART; SM00191; Int_alpha; 5.
DR   SUPFAM; SSF69179; SSF69179; 3.
DR   PROSITE; PS51470; FG_GAP; 7.
DR   PROSITE; PS00242; INTEGRIN_ALPHA; 1.
PE   2: Evidence at transcript level;
KW   Cell adhesion {ECO:0000256|RuleBase:RU003762,
KW   ECO:0000256|SAAS:SAAS01101218};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008225};
KW   Integrin {ECO:0000256|RuleBase:RU003762,
KW   ECO:0000256|SAAS:SAAS00414648, ECO:0000313|EMBL:JAB09391.1};
KW   Membrane {ECO:0000256|RuleBase:RU003762,
KW   ECO:0000256|SAAS:SAAS00414656};
KW   Receptor {ECO:0000256|RuleBase:RU003762,
KW   ECO:0000256|SAAS:SAAS01101220};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW   Repeat {ECO:0000256|SAAS:SAAS00048613};
KW   Transmembrane {ECO:0000256|RuleBase:RU003762,
KW   ECO:0000256|SAAS:SAAS00494686};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU003762,
KW   ECO:0000256|SAAS:SAAS00414628}.
FT   TRANSMEM     12     33       Helical. {ECO:0000256|RuleBase:RU003762}.
FT   TRANSMEM   1042   1064       Helical. {ECO:0000256|RuleBase:RU003762}.
FT   REPEAT       35    103       FG-GAP. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00803}.
FT   REPEAT      110    175       FG-GAP. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00803}.
FT   REPEAT      185    238       FG-GAP. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00803}.
FT   REPEAT      253    309       FG-GAP. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00803}.
FT   REPEAT      310    371       FG-GAP. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00803}.
FT   REPEAT      372    427       FG-GAP. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00803}.
FT   REPEAT      431    490       FG-GAP. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00803}.
FT   DOMAIN      475    966       Integrin_alpha2. {ECO:0000259|Pfam:
FT                                PF08441}.
SQ   SEQUENCE   1141 AA;  124751 MW;  E444063035204C85 CRC64;
     MAGARSRDPW GASWICYFFG SLLVELLFSR AVAFNLDVMG ALRKEGEPGS LFGFSVALHR
     QLQPRPQSWL LVGAPQALAL PGQQANRTGG LFACPLSLEE TDCYRVDIDQ GADVQKESKE
     NQWLGVSVRS QAPGGKIVTC AHRYEARQRV DQILETRDMI GRCFVLSQDL AIRDELDGGE
     WKFCEGRPQG HEQFGFCQQG TAAAFSPDSH YLLFGAPGTY NWKGTARVEL CAQGSADLAH
     LDDGPYEAGG EKQQDPRLIP VPANSYFGFS IDSGKGLVRA EELSFVAGAP RANHRGAVVI
     LRKDSASRLV PEAVLSGERL TSGFGYSLAV ADLNSDGWPD LIVGAPYFFE RQEELGGAVY
     VYLNQGGHWT GISPLRLCGS PDSMFGISVA VLGDLNQDGF PDIAVGAPFD GDGKVFIYHG
     SSLGIVAKPS QVLEGEAVGI KSFGYSLSGN LDMDGNQYPD LLVGSLADSA VLFRARPVLH
     VSHEVSIAPR SIDLEQPNCA GGHLVCVDLR VCFSYIAVPR SYNPTVALDY VLDGDTDRRL
     RGQVPRVIFL RRSPDEPKHQ ASGTVWLKHQ HDRVCGDAMF QLQENIKDKL RAIVVTLSYS
     LPTPRLRRQA PGQGLPPVAP ILNAHQSSTQ RAEIHFLKQG CGEDKICQSN LQLVRARFCA
     RVSDTEFQPL PMDADGTTAL FALSGQPVIG LELMVTNLPS DPAQPQADGD DAHEAQLLVM
     LPASLHYSGV RALDPAEKPL CLSNENASHV ECELGNPMKR GAQVTFYLIF STSGISIETT
     ELEVKLLLAT ISEQELHVVS ARARVFIELP LSIAGMAIPQ QLFFSGVVRG ESAMQSERDV
     GSKVKYEVTV SNQGQSLKTL GSAFLNIMWP HEIANGKWLL YPMRVELEGG QGPGQKGLCS
     PRPNILHLDV DSRDRRRREL ELPEQPEPGE QQEPSMSWWP VSSAEKKKNI TLDCARGTAN
     CVVFSCPLYS FDRAAVLRVW GRLWNSTFLE EYSAVKSLEV IVRANITVKS SIKNLMLRDA
     STVIPVMVYL DPVAVVAEGV PWWVILLAVL AGLLVLALMV LLLWKMGFFK RAKHPEATVP
     QYHAVKIPRE DRQQFKEEKT GTILRSNWGS PRREGPDAHP ILAADGHPEL GLDGHPGPGT
     A
//
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