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Database: UniProt
Entry: F7F2R9_MONDO
LinkDB: F7F2R9_MONDO
Original site: F7F2R9_MONDO 
ID   F7F2R9_MONDO            Unreviewed;      3155 AA.
AC   F7F2R9;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 2.
DT   05-JUN-2019, entry version 59.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMODP00000022331};
GN   Name=REV3L {ECO:0000313|Ensembl:ENSMODP00000022331};
OS   Monodelphis domestica (Gray short-tailed opossum).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Metatheria; Didelphimorphia; Didelphidae; Monodelphis.
OX   NCBI_TaxID=13616 {ECO:0000313|Ensembl:ENSMODP00000022331, ECO:0000313|Proteomes:UP000002280};
RN   [1] {ECO:0000313|Ensembl:ENSMODP00000022331, ECO:0000313|Proteomes:UP000002280}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17495919; DOI=10.1038/nature05805;
RA   Mikkelsen T.S., Wakefield M.J., Aken B., Amemiya C.T., Chang J.L.,
RA   Duke S., Garber M., Gentles A.J., Goodstadt L., Heger A., Jurka J.,
RA   Kamal M., Mauceli E., Searle S.M., Sharpe T., Baker M.L., Batzer M.A.,
RA   Benos P.V., Belov K., Clamp M., Cook A., Cuff J., Das R., Davidow L.,
RA   Deakin J.E., Fazzari M.J., Glass J.L., Grabherr M., Greally J.M.,
RA   Gu W., Hore T.A., Huttley G.A., Kleber M., Jirtle R.L., Koina E.,
RA   Lee J.T., Mahony S., Marra M.A., Miller R.D., Nicholls R.D., Oda M.,
RA   Papenfuss A.T., Parra Z.E., Pollock D.D., Ray D.A., Schein J.E.,
RA   Speed T.P., Thompson K., VandeBerg J.L., Wade C.M., Walker J.A.,
RA   Waters P.D., Webber C., Weidman J.R., Xie X., Zody M.C., Baldwin J.,
RA   Abdouelleil A., Abdulkadir J., Abebe A., Abera B., Abreu J.,
RA   Acer S.C., Aftuck L., Alexander A., An P., Anderson E., Anderson S.,
RA   Arachi H., Azer M., Bachantsang P., Barry A., Bayul T., Berlin A.,
RA   Bessette D., Bloom T., Bloom T., Boguslavskiy L., Bonnet C.,
RA   Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA   Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P.,
RA   Costello M., D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C.,
RA   Dhargay N., Dooley K., Dooley E., Doricent M., Dorje P., Dorjee K.,
RA   Dupes A., Elong R., Falk J., Farina A., Faro S., Ferguson D.,
RA   Fisher S., Foley C.D., Franke A., Friedrich D., Gadbois L., Gearin G.,
RA   Gearin C.R., Giannoukos G., Goode T., Graham J., Grandbois E.,
RA   Grewal S., Gyaltsen K., Hafez N., Hagos B., Hall J., Henson C.,
RA   Hollinger A., Honan T., Huard M.D., Hughes L., Hurhula B., Husby M.E.,
RA   Kamat A., Kanga B., Kashin S., Khazanovich D., Kisner P., Lance K.,
RA   Lara M., Lee W., Lennon N., Letendre F., LeVine R., Lipovsky A.,
RA   Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y., Lubonja R.,
RA   Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA   McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA   Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A.,
RA   Mulrain L., Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N.,
RA   Nicol R., Norbu C., Norbu N., Novod N., O'Neill B., Osman S.,
RA   Markiewicz E., Oyono O.L., Patti C., Phunkhang P., Pierre F.,
RA   Priest M., Raghuraman S., Rege F., Reyes R., Rise C., Rogov P.,
RA   Ross K., Ryan E., Settipalli S., Shea T., Sherpa N., Shi L., Shih D.,
RA   Sparrow T., Spaulding J., Stalker J., Stange-Thomann N.,
RA   Stavropoulos S., Stone C., Strader C., Tesfaye S., Thomson T.,
RA   Thoulutsang Y., Thoulutsang D., Topham K., Topping I., Tsamla T.,
RA   Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M., Wilkinson J.,
RA   Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D., Zimmer A.,
RA   Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J., Chin C.,
RA   Gnerre S., MacCallum I., Graves J.A., Ponting C.P., Breen M.,
RA   Samollow P.B., Lander E.S., Lindblad-Toh K.;
RT   "Genome of the marsupial Monodelphis domestica reveals innovation in
RT   non-coding sequences.";
RL   Nature 447:167-177(2007).
RN   [2] {ECO:0000313|Ensembl:ENSMODP00000022331}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   RefSeq; XP_007484500.1; XM_007484438.2.
DR   STRING; 13616.ENSMODP00000022331; -.
DR   Ensembl; ENSMODT00000022721; ENSMODP00000022331; ENSMODG00000017910.
DR   GeneID; 100022401; -.
DR   CTD; 5980; -.
DR   eggNOG; KOG0968; Eukaryota.
DR   eggNOG; COG0417; LUCA.
DR   GeneTree; ENSGT00940000156226; -.
DR   InParanoid; F7F2R9; -.
DR   OMA; CSKCRSQ; -.
DR   OrthoDB; 20210at2759; -.
DR   TreeFam; TF101072; -.
DR   Proteomes; UP000002280; Chromosome 2.
DR   Bgee; ENSMODG00000017910; Expressed in 7 organ(s), highest expression level in cerebellum.
DR   GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR   GO; GO:0016035; C:zeta DNA polymerase complex; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0042276; P:error-prone translesion synthesis; IBA:GO_Central.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IEA:GOC.
DR   Gene3D; 1.10.132.60; -; 1.
DR   Gene3D; 3.30.420.10; -; 1.
DR   Gene3D; 3.90.1600.10; -; 1.
DR   InterPro; IPR006172; DNA-dir_DNA_pol_B.
DR   InterPro; IPR017964; DNA-dir_DNA_pol_B_CS.
DR   InterPro; IPR006133; DNA-dir_DNA_pol_B_exonuc.
DR   InterPro; IPR006134; DNA-dir_DNA_pol_B_multi_dom.
DR   InterPro; IPR042087; DNA_pol_B_C.
DR   InterPro; IPR023211; DNA_pol_palm_dom_sf.
DR   InterPro; IPR032757; DUF4683.
DR   InterPro; IPR030559; PolZ_Rev3.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR025687; Znf-C4pol.
DR   PANTHER; PTHR45812; PTHR45812; 1.
DR   Pfam; PF00136; DNA_pol_B; 1.
DR   Pfam; PF03104; DNA_pol_B_exo1; 2.
DR   Pfam; PF15735; DUF4683; 1.
DR   Pfam; PF14260; zf-C4pol; 1.
DR   PRINTS; PR00106; DNAPOLB.
DR   SMART; SM00486; POLBc; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
DR   PROSITE; PS00116; DNA_POLYMERASE_B; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002280};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002280}.
FT   DOMAIN       46    203       DNA_pol_B_exo1. {ECO:0000259|Pfam:
FT                                PF03104}.
FT   DOMAIN      748   1135       DUF4683. {ECO:0000259|Pfam:PF15735}.
FT   DOMAIN     2303   2509       DNA_pol_B_exo1. {ECO:0000259|Pfam:
FT                                PF03104}.
FT   DOMAIN     2576   3025       DNA_pol_B. {ECO:0000259|Pfam:PF00136}.
FT   DOMAIN     3067   3134       zf-C4pol. {ECO:0000259|Pfam:PF14260}.
FT   REGION      270    294       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F7F2R9}.
FT   REGION      429    460       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F7F2R9}.
FT   REGION      492    512       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F7F2R9}.
FT   REGION      527    551       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F7F2R9}.
FT   REGION      603    645       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F7F2R9}.
FT   REGION     1037   1097       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F7F2R9}.
FT   REGION     1161   1235       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F7F2R9}.
FT   REGION     1261   1288       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F7F2R9}.
FT   REGION     1553   1605       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F7F2R9}.
FT   REGION     1739   1759       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F7F2R9}.
FT   REGION     1861   1888       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F7F2R9}.
FT   REGION     1975   2000       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F7F2R9}.
FT   REGION     2112   2207       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F7F2R9}.
FT   REGION     2232   2267       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F7F2R9}.
FT   REGION     2276   2295       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F7F2R9}.
FT   COMPBIAS    432    450       Polar. {ECO:0000256|MobiDB-lite:F7F2R9}.
FT   COMPBIAS    603    640       Polar. {ECO:0000256|MobiDB-lite:F7F2R9}.
FT   COMPBIAS   1043   1081       Basic. {ECO:0000256|MobiDB-lite:F7F2R9}.
FT   COMPBIAS   1082   1097       Polar. {ECO:0000256|MobiDB-lite:F7F2R9}.
FT   COMPBIAS   1200   1235       Polyampholyte. {ECO:0000256|MobiDB-lite:
FT                                F7F2R9}.
FT   COMPBIAS   1553   1586       Polar. {ECO:0000256|MobiDB-lite:F7F2R9}.
FT   COMPBIAS   1861   1887       Polar. {ECO:0000256|MobiDB-lite:F7F2R9}.
FT   COMPBIAS   1975   1997       Polar. {ECO:0000256|MobiDB-lite:F7F2R9}.
FT   COMPBIAS   2157   2175       Polyampholyte. {ECO:0000256|MobiDB-lite:
FT                                F7F2R9}.
FT   COMPBIAS   2190   2207       Polar. {ECO:0000256|MobiDB-lite:F7F2R9}.
FT   COMPBIAS   2250   2264       Polyampholyte. {ECO:0000256|MobiDB-lite:
FT                                F7F2R9}.
SQ   SEQUENCE   3155 AA;  355373 MW;  EE52AAADA8D7D4AB CRC64;
     MFSVRIVTAD YYMASPLQGL DICQSPFTQA PVKKVPVVRV FGATPAGQKT CLHLHGIFPY
     LYVPYDGCGQ QPERYLRQMA FSIDRALNVA LGNPSSTVQH VFKVSLVSGM PFYGYHEKER
     HFMKIYLYNP AMVKRICELL QSGAIMNKYY QPHEAHIPYL LQLFIDYNLY GMNLINLAAV
     RFRKVKRKSD TLHGIGCYKD QLPGNSLTGT LFRWEEDEIP SSLILEGVEP QSTCELEVDA
     VAADILNRLE IEAQIGGNPG LQAIWEDEKQ RRRNRNESSQ ISHPESQDRR CVPATESEKM
     FQKRLQEVLK QNDFSVTLSG SVDYSNGSQE FSAELTLHSE VLSTETVPCS PANVVEVHQE
     KELSKECFKK NILKEEEALI NEEAILNLME TSQTFQPLSQ RLSQSPIFMD SNPDESLVHL
     LAGLESDGYQ GKRHGISSSH PSFGSSRNPQ NSDDEENEPQ IEKEEMELSL LMSQRWDSNI
     EDHCAEKRSP CRNIHRSSTE EEDSSSEEEM EWSGNNLLLA NLSIPQLDGT ADENSDNPLN
     NESSRTHSSV IATSKMSVKT SIFHKDAATL EPPSSAKITF PCKHTSALSS HVLNKEDLIE
     DLSQPNNIET GPDHTVHSLT NESPYSMKYP GSLSSTVHSE NSHKESSKKE IFAVSSCESS
     IFDYEEDISS LNRQISNRKY TSIRKVEKDA SFMHMSHHIN ESTLGKNFNF SDLSHSKNKL
     TSEGTEKGSS TALNNFFPSS LTENCELVSC SGESRTMVHS VEGASDEGGI SKLKIRYEEF
     QEHKIEKPSL SQQAAHYMFF PSVVLSNCLS RPQKLSPVTY KLQPGNKQSR LKLSKKKLVD
     HQENPPSIND IGSTKEGCYL QGSTCSTNSE KDDALSNDVI RVAREAFENK APADSCIDCH
     FGDGTLESEQ SFGLFGNKYT LRAKRKVNYE TEDSESSFVT HNSKISLPQS MEIGESLDGS
     LKSRKRRKMS KKLPPVIIKY IIINRFRGRK NMLVKLGKID SKEKQVILTE EKMDLYKKLA
     PLKDFWPKVP DSPATKYPIY PLTPKKSHRR KAKHKSAKKK TGKQQKTNNK NIKRTLSFRK
     KRSHTILSPP SPSYNAETED CDLNYSDVMS KLGFLSERST SPVNSSPPRC WSPTDPRAEE
     IITASDKEAL LLFKGPNIYN SKAINSSMGK NSRAKAQVKK SKTKLVNPSV VSKKRNKRTQ
     TRKPGEDGRK KPRAKQKQKI SEKGSTSRKH ITFKDEKINT QTNAEVKFVI KHQDLSETAN
     NFGGSQSLNK QKDVSVPSPA TIHPLSTPLP SIVNVQQKSP GCFPSSLENK SIDLQAFSSP
     QDDLCSSLVS TPIGTGKELS KMNTQWSHNQ STIFSIKEST LIQNNIFDLS NHLSQVAQNT
     QLSLNMMSTK AEENANSHKK ILSSVGKLNE HHSSLDSVKS DQLHAPNFLH CKDSQQHIVC
     MPEPSKHSDP YSPIHIASEE NHGSLQLPNN CFVTSLRSPI KQIAWEQKQR GFILDMSSFK
     PERVKQRSLS EAISQTKALS QCKNRNVSAA AFGEGQSGLA VLKELLQKRQ QKAQNAHVMQ
     DPISSKPQLN RSISCSLEPN KAVKRSRSVT SPRKPRTTRS TKPKEKIPKI LKLDSLNLQN
     TGQIDHSISD DSPIFFSDPG FESCYSLEDS LSPEHNYNFD INTIGQTGFC SFYSGSQFVP
     ADQNLPQKFL SDAVQDLFPA QTTENEFLSH DSQKCDENKH LSADPASWIR SGALSPELFD
     KPPVEGNENH RHSQWKNSLH PLSSRSNSIM DSFCVQQPGE CINEKSILSR NSVSKEVFLS
     LPQPSDSNWI QNHTRKETSF DTVQSLDSIN TSFTAILSSP DGELVDAASE DLELYVSRNN
     EMLTPTPDSS PRSTSSPSQS KNGSFTPRTA HILKPLMSPP SREEIMATLL DHDLAETIYQ
     EPFCSNPSDA PEKPREIGGR LLMVETRLPN DLAEFEGDFS LEGLRLWKTA FSAMTQNPRS
     GSPPRNGQAV ASKGSNNSHK TMEDKKIVIM PCKCAPSPQL VQAWLQAKEE YERSKKLPKI
     EPTEIVKSTE NLGYPVNQDD RPVVPPQNDT VLHVAPSTTG IKEDLCNSEL RAQVPKGNST
     ECRTVVESQT LPIVSSAGEP EKDDAEDDDY YVSYSSPDSP VLPPWQQAAS PDSKLLDVND
     KSCKINHKDP SPKEELNSFP MESFPKAKNG IQDSPHSETQ ETQTKSPCQF RAKNGKCDSY
     CLHSTPIIQR RHLDRLPEAN DISPLSRDPK TQKLTHRKGS SPDSLKKRIL LTTQAKNQFT
     AVNTPKKESS QIDGPSLNNT YGFKVSVQNL QEAKALHEIQ NLTLISVELH ARTRRDLEPD
     PEFDPICALF YSISSDTALP DTDKTELTGV IVIDKDSTIS NQGIRNQTPL LIRSGITRLE
     VTYAADEKAL FQEIVNIIKR YDPDILLGYE IQMHSWGYLL QRAAALSVDL CQMISRVPDD
     KTENRFAAER DEYGSDTMSE INIVGRITLN LWRIMRNEVA LTNYTFENVS FHVLHQRFPL
     FTFRVLSDWF DNKTDLYRWK MVDHYVSRVR GNLQMLEQLD LIGKTSEMAR LFGIQFLHVL
     TRGSQYRVES MMLRIAKPMN YIPVTPSMQQ RAQMRAPQCV PLIMEPESRF YSNSVLVLDF
     QSLYPSIVIA YNYCFSTCLG HVENLGKFDE YKFGCTSLRV PPDLLYQIRH DITVSPNGVA
     FVKPSVRKGV LPRMLEEILK TRFMVKQSMK TYKQDRALSR MLNARQLGLK LIANVTFGYT
     AANYSGRMPC IEVGDSIVHK ARETLERAIK LVNDTKKWGA RVVYGDTDSM FVLLKGATKE
     QSFKIGQEIA EAVTATNPKP VKLKFEKVYL PCVLQTKKRY VGYMYETLDQ KDPVFDAKGI
     ETVRRDSCPA VSKILERSIK LLFETRDISQ IKQYVQRQCI KLLEGKASLQ DVIFAKEYRG
     SSSYKPGACV PALELTRKML AYDRRSEPRV GERVPYVIVY GLPGIPLIQL VRRPLEVLQD
     SSLRLNATYY ITKQILPPLA RIFSLIGIDV FSWYHELPRI QKVTTSAHSE HEGRKGTISQ
     YFTTLHCPVC DELTQHGICS KCRSQPQHVA IVLNQEIREW ERQQEQLVKI CKNCTGCCDR
     QIQCVSLNCP ILFKLSRVSR ELSKAPYLRQ LLDQF
//
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