GenomeNet

Database: UniProt
Entry: F7FBB2_MACMU
LinkDB: F7FBB2_MACMU
Original site: F7FBB2_MACMU 
ID   F7FBB2_MACMU            Unreviewed;      3109 AA.
AC   F7FBB2;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 2.
DT   03-JUL-2019, entry version 58.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMUP00000028357};
GN   Name=REV3L {ECO:0000313|Ensembl:ENSMMUP00000028357,
GN   ECO:0000313|VGNC:VGNC:76900};
OS   Macaca mulatta (Rhesus macaque).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9544 {ECO:0000313|Ensembl:ENSMMUP00000028357, ECO:0000313|Proteomes:UP000006718};
RN   [1] {ECO:0000313|Ensembl:ENSMMUP00000028357, ECO:0000313|Proteomes:UP000006718}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000028357,
RC   ECO:0000313|Proteomes:UP000006718};
RX   PubMed=17431167; DOI=10.1126/science.1139247;
RA   Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M.,
RA   Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C.,
RA   Wilson R.K., Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W.,
RA   Hardison R.C., Makova K.D., Miller W., Milosavljevic A., Palermo R.E.,
RA   Siepel A., Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J.,
RA   Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y.,
RA   Dinh H.H., Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T.,
RA   Godfrey J., Hawes A.C., Hernandez J., Hines S., Holder M., Hume J.,
RA   Jhangiani S.N., Joshi V., Khan Z.M., Kirkness E.F., Cree A.,
RA   Fowler R.G., Lee S., Lewis L.R., Li Z., Liu Y.-S., Moore S.M.,
RA   Muzny D., Nazareth L.V., Ngo D.N., Okwuonu G.O., Pai G., Parker D.,
RA   Paul H.A., Pfannkoch C., Pohl C.S., Rogers Y.-H.C., Ruiz S.J.,
RA   Sabo A., Santibanez J., Schneider B.W., Smith S.M., Sodergren E.,
RA   Svatek A.F., Utterback T.R., Vattathil S., Warren W., White C.S.,
RA   Chinwalla A.T., Feng Y., Halpern A.L., Hillier L.W., Huang X.,
RA   Minx P., Nelson J.O., Pepin K.H., Qin X., Sutton G.G., Venter E.,
RA   Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P., Jones S.M.,
RA   Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L., Csuros M.,
RA   Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H., Liu Y.,
RA   Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E.,
RA   Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J.,
RA   Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J.,
RA   Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A.,
RA   Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J.,
RA   Denby A., Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A.,
RA   Marklein A., Nielsen R., Vallender E.J., Clark A.G., Ferguson B.,
RA   Hernandez R.D., Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S.,
RA   Pu L.-L., Ren Y., Smith D.G., Wheeler D.A., Schenck I., Ball E.V.,
RA   Chen R., Cooper D.N., Giardine B., Hsu F., Kent W.J., Lesk A.,
RA   Nelson D.L., O'brien W.E., Pruefer K., Stenson P.D., Wallace J.C.,
RA   Ke H., Liu X.-M., Wang P., Xiang A.P., Yang F., Barber G.P.,
RA   Haussler D., Karolchik D., Kern A.D., Kuhn R.M., Smith K.E.,
RA   Zwieg A.S.;
RT   "Evolutionary and biomedical insights from the rhesus macaque
RT   genome.";
RL   Science 316:222-234(2007).
RN   [2] {ECO:0000313|Ensembl:ENSMMUP00000028357}
RP   IDENTIFICATION.
RC   STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000028357};
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; JSUE03032475; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; JSUE03032476; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; JSUE03032477; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; JSUE03032478; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 9544.ENSMMUP00000028357; -.
DR   Ensembl; ENSMMUT00000030304; ENSMMUP00000028357; ENSMMUG00000021533.
DR   VGNC; VGNC:76900; REV3L.
DR   eggNOG; KOG0968; Eukaryota.
DR   eggNOG; COG0417; LUCA.
DR   GeneTree; ENSGT00940000156226; -.
DR   InParanoid; F7FBB2; -.
DR   TreeFam; TF101072; -.
DR   Proteomes; UP000006718; Chromosome 4.
DR   Bgee; ENSMMUG00000021533; Expressed in 14 organ(s), highest expression level in Ammon's horn.
DR   ExpressionAtlas; F7FBB2; baseline.
DR   GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR   GO; GO:0016035; C:zeta DNA polymerase complex; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0042276; P:error-prone translesion synthesis; IBA:GO_Central.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IEA:GOC.
DR   Gene3D; 1.10.132.60; -; 1.
DR   Gene3D; 3.30.420.10; -; 1.
DR   Gene3D; 3.90.1600.10; -; 1.
DR   InterPro; IPR006172; DNA-dir_DNA_pol_B.
DR   InterPro; IPR017964; DNA-dir_DNA_pol_B_CS.
DR   InterPro; IPR006133; DNA-dir_DNA_pol_B_exonuc.
DR   InterPro; IPR006134; DNA-dir_DNA_pol_B_multi_dom.
DR   InterPro; IPR042087; DNA_pol_B_C.
DR   InterPro; IPR023211; DNA_pol_palm_dom_sf.
DR   InterPro; IPR032757; DUF4683.
DR   InterPro; IPR030559; PolZ_Rev3.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR025687; Znf-C4pol.
DR   PANTHER; PTHR45812; PTHR45812; 1.
DR   Pfam; PF00136; DNA_pol_B; 1.
DR   Pfam; PF03104; DNA_pol_B_exo1; 2.
DR   Pfam; PF15735; DUF4683; 1.
DR   Pfam; PF14260; zf-C4pol; 1.
DR   PRINTS; PR00106; DNAPOLB.
DR   SMART; SM00486; POLBc; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
DR   PROSITE; PS00116; DNA_POLYMERASE_B; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006718};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006718}.
FT   DOMAIN       46    191       DNA_pol_B_exo1. {ECO:0000259|Pfam:
FT                                PF03104}.
FT   DOMAIN      747   1133       DUF4683. {ECO:0000259|Pfam:PF15735}.
FT   DOMAIN     2290   2481       DNA_pol_B_exo1. {ECO:0000259|Pfam:
FT                                PF03104}.
FT   DOMAIN     2548   2990       DNA_pol_B. {ECO:0000259|Pfam:PF00136}.
FT   DOMAIN     3021   3088       zf-C4pol. {ECO:0000259|Pfam:PF14260}.
FT   REGION      270    297       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F7FBB2}.
FT   REGION      425    457       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F7FBB2}.
FT   REGION      487    510       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F7FBB2}.
FT   REGION      524    548       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F7FBB2}.
FT   REGION      839    872       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F7FBB2}.
FT   REGION     1035   1096       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F7FBB2}.
FT   REGION     1166   1222       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F7FBB2}.
FT   REGION     1545   1596       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F7FBB2}.
FT   REGION     1844   1872       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F7FBB2}.
FT   REGION     1961   1983       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F7FBB2}.
FT   REGION     2017   2148       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F7FBB2}.
FT   REGION     2214   2233       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F7FBB2}.
FT   COILED     3044   3067       {ECO:0000256|SAM:Coils}.
FT   COMPBIAS    843    872       Polar. {ECO:0000256|MobiDB-lite:F7FBB2}.
FT   COMPBIAS   1041   1060       Basic. {ECO:0000256|MobiDB-lite:F7FBB2}.
FT   COMPBIAS   1195   1209       Polyampholyte. {ECO:0000256|MobiDB-lite:
FT                                F7FBB2}.
FT   COMPBIAS   1545   1565       Polar. {ECO:0000256|MobiDB-lite:F7FBB2}.
FT   COMPBIAS   1574   1588       Basic. {ECO:0000256|MobiDB-lite:F7FBB2}.
FT   COMPBIAS   1844   1871       Polar. {ECO:0000256|MobiDB-lite:F7FBB2}.
FT   COMPBIAS   1961   1982       Polar. {ECO:0000256|MobiDB-lite:F7FBB2}.
FT   COMPBIAS   2064   2096       Polar. {ECO:0000256|MobiDB-lite:F7FBB2}.
FT   COMPBIAS   2218   2233       Polar. {ECO:0000256|MobiDB-lite:F7FBB2}.
SQ   SEQUENCE   3109 AA;  350476 MW;  F3D44274496010F0 CRC64;
     MFSVRIVTAD YYMASPLQGL DTCQSPLTQA PVKKVPVVRI FGATPAGQKT CLHLHGIFPY
     LYVPYDGYGQ QPESYLSQMA FSIDRALNVA LGNPSSTAQH VFKVSLVSGM PFYGYHEKER
     HFMKIYLYNP AVVKRICELL QSGAIMNKFY QPHEAHIPYL LQLFIDYNLY GMNLINLAAV
     KFRKARRKSN TLYATGSCKN HLSRNSLAGT LFRWEQDEIP SSLILEGVEP QSTCELEVDA
     VAADILNRLD IEAQIGGNPG LQAIWEDEKQ RRRNRNETSQ ISQPESQDHR FVPATESEKK
     FQKRLQEILK QNDFSVTLSG SVDYSDGSQE FSAELTLHSE VLSPEMLQCT PANMVEVHKD
     KESSKGHTRH KVEEALINEE AILNLMENSQ TFQPLTQRLS ESPVFMDSSP DEALVHLLAG
     LESDGYRGER NRMPSPCRSF GNNKYPQNSD DEENEPQIEK EEMELSLVMS QRWDSNIEEH
     CAKKRSLCRN THRSSTEDDD SSSEEEMEWS DNSLLLANLS IPQLDGTADE NSDNPLNNEN
     SRTHSSVIAT SKLSVKPSIF HKDAATLEPS SSAKITFQCK HTSALSSHVL NKEDLIEDLS
     QTNKNIEKGL DNSVTSFTNE STYSVKYPGS LSSTVHSENS HKENSKKEIL PVSSCESSIF
     DYEEDIPSVT RQVPSRKYTN IRKIEKDSPF IHMHRHPNEN TLGKNSFNFS DLNHSKNKVS
     SEGNEKGNST ALSSLFPSSF TENCELLSCS GENRTMVHSL NSTADESGLN KLKIRYEEFQ
     EHKTEKPSLS QQAAHYMFFP SVVLSNCLTR PQKLSPVTYK LQPGNKPSRL KLNKKKLAGH
     QETFTKSSET GSTKDNSIQN NPCNSNPEKD SAFASDLTKT SRGAFENKTP TDGFIDCHFG
     DGTLETEQSF GLYGNKYTLR AKRKVNYETE DSESSFVTHN SKISLPHPME IGESLDGTLK
     SRKRRKMSKK LPPVIIKYII INRFRGRKNM LVKLGKIDAK EKQVILTEEK MELYKKLAPL
     KDFWPKVPDS PATKYPIYPL TPKKSHRRKS KHKSAKKKTG KQQRTNNENI KRTLSFRKKR
     SHALLSPPSP SYNAETEDCD LNYSDVMSKL GFLSERSTSP INSSPPRCWS PTDPRAEEIM
     AAAEKEAMLF KGPNVYNKTV NSRIGKNSRA RAQVKKSKAK LVNPSVVTKK RNKRNQTNKL
     VDDGKKKPRA KQKTNAKGTS RKHITLKDEK IKSQSGAEVK FVLKHQNVSE FASSSGGAQL
     LFKQKDMPLM GSAVDHPLSA PLPTGINAQQ KLSGCFSSFL ESKKSVDVQT FPSSRDDLHP
     SVVCNSIGPG ISKINVQRPH NQSAIFTLKE STLIQKNVFD LSNHLSQVAQ NTQISSGMSS
     KIEDNANNIQ KNYLSSIGKL SEYRNSLESK LDQAYTPNFL HCKDSQQQIV CIAEQSKHSE
     TCSPGNTASD ESQMPNNCFV TSLRSPIKQI AWEQKQRGFI LDMSNFKPER VKQRSLSEAI
     SQTKALSQCK NRNVSAPSAF GEGQSGLAVL KELLQKRQQK AQNANIIQDP LSNKHQPNKN
     ISGSLEHNKA NKRTRSVTSP RKPRTPRSTK PKEKIPKLLK VDSLNLQNSS QLDNSVSDDS
     PIFFSDPGFE SCYSLEDSLS PEHNYNFDIN TIGQTGFCSF YSGSQFVPAD QNLPQKFLSD
     AVQDLFPGQA IEKNEFLSHD NQKCEEDKHT TDSASWIRSG TLSPEIFEKS SIDSIENHRH
     NQWKNSFHPL TTRSNSIMDS FCVQQAEDCL NEKSRLNRSS VSKEVFLSLP QPNNSDWIQG
     HTRKEMGRSL DSANTSFTAI LSSPDGELVD MACEDLELYV SRNNDMLTPT PDSSPRSTSS
     PSQSKNGSFT PRTAHILKPL MSPPSREEIM ATLLDHDLSE TIYQEPFCSN PSDVPEKPRE
     IGGRLLMVET RLANDLAEFE GDFSLEGLRL WKTAFSAMTQ NPRPGSPLRS GQGVVNKGSS
     NSPKMVEDKK IVIMPCKCAP SRQLVQVWLQ AKEQYERSKK LPKTKPTGVV KSAENFSSSV
     NPDDKPVVPP KMDVSPRILP TTAHTKEDVN SRIALQAPTT GCSQTASESQ MLPPVASSSD
     PEKDEDDDNY YINYSSPDSP VIPPWQQPVS PDSKALNGDD RPSSPVEELP SLAVENFLKP
     IKDGIQKSPC SEPQEPLVIS PINARARTEK CESLCLHSTP IIQRKLLERL PEATGLSPLS
     TEPKTQKLSN KKGSNTDTLR RVLLTQAKNQ FAAVNTPQKE TSQIDGPSLN NTYGFKVSIQ
     NLQEAKALHE IQNLTLISVE LHARTRRDLE PDPEFDPICA LFYCISSDAP LPDTEKTELT
     GVIVIDKDKT VFSQDIRYQT PLLIRSGITG LEVTYAADEK ALFHEIAHII KRYDPDILLG
     YEIQMHSWGY LLQRAAALSV DLCQMISRVP DDKIENRFAA ERDEYGSYTM SEINIVGRIT
     LNLWRIMRNE VALTNYTFEN VSFHVLHQRF PLFTFRVLSD WFDNKTDLYR WKMVDHYVSR
     VRGNLQMLEQ LDLIGKTSEM ARLFGIQFLH VLTRGSQYRV ESMMLRIAKP MNYIPVTPSV
     QQRSQMRAPQ CVPLIMEPES RFYSNSVLVL DFQSLYPSIV IAYNYCFSTC LGHVENLGKY
     DEFKFGCTSL RVPPDLLYQV RHDITVSPNG VAFVKPSVRK GVLPRMLEEI LKTRFMVKQS
     MKAYKQDRAL SRMLDARQLG LKLIANVTFG YTAANFSGRM PCIEVGDSIV HKARETLERA
     IKLVNDTKKW GARVVYGDTD SMFVLLKGAT KEQSFKIGQE IAEAVTATNP KPVKLKFEKV
     YLPCVLQTKK RYVGYMYETL DQKDPVFDAK GIETVRRDSC PAVSKILERS LKLLFETRDI
     SLIKQYVQRQ CMKLLEGKAS IQDFIFAKEY RGSFSYKPGA CVPALELTRK MLTYDRRSEP
     QVGERVPYVI IYGTPGVPLI QLVRRPVEVL QDPTLRLNAT YYITNWYHEI RPRIHKATNS
     SRSEPEGRKG TISQYFTTLH CPVCDDLTQH GICSKCRSQP QHVAVILNQE IRELERKQEQ
     LVKICKNCTG CFDRHIPCVS LNCPVLFKVS RVNRELSKAP YLRQLLDQF
//
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