ID F7FEC3_CALJA Unreviewed; 249 AA.
AC F7FEC3;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Pleckstrin homology and FYVE domain containing 2 {ECO:0000313|Ensembl:ENSCJAP00000060585.1};
DE SubName: Full=Pleckstrin homology domain-containing family F member 2 {ECO:0000313|EMBL:JAB35828.1};
GN Name=PLEKHF2 {ECO:0000313|EMBL:JAB35828.1,
GN ECO:0000313|Ensembl:ENSCJAP00000060585.1};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|EMBL:JAB35828.1};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000060585.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:JAB35828.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Bladder {ECO:0000313|EMBL:JAB05927.1}, Cerebellum
RC {ECO:0000313|EMBL:JAB46113.1}, Cerebral cortex
RC {ECO:0000313|EMBL:JAB25384.1}, Hippocampus
RC {ECO:0000313|EMBL:JAB15985.1}, and Skeletal muscle
RC {ECO:0000313|EMBL:JAB35828.1};
RX PubMed=25243066; DOI=10.1186/2047-217X-3-14;
RA Maudhoo M.D., Ren D., Gradnigo J.S., Gibbs R.M., Lubker A.C.,
RA Moriyama E.N., French J.A., Norgren R.B.Jr.;
RT "De novo assembly of the common marmoset transcriptome from NextGen mRNA
RT sequences.";
RL Gigascience 3:14-14(2014).
RN [3] {ECO:0000313|Ensembl:ENSCJAP00000060585.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; GAMT01005934; JAB05927.1; -; mRNA.
DR EMBL; GAMS01007151; JAB15985.1; -; mRNA.
DR EMBL; GAMR01008548; JAB25384.1; -; mRNA.
DR EMBL; GAMQ01006023; JAB35828.1; -; mRNA.
DR EMBL; GAMP01006642; JAB46113.1; -; mRNA.
DR RefSeq; XP_008981178.1; XM_008982930.2.
DR RefSeq; XP_008981179.1; XM_008982931.1.
DR RefSeq; XP_008981181.1; XM_008982933.2.
DR STRING; 9483.ENSCJAP00000060585; -.
DR Ensembl; ENSCJAT00000067605.2; ENSCJAP00000060585.1; ENSCJAG00000047758.2.
DR GeneID; 100409564; -.
DR KEGG; cjc:100409564; -.
DR CTD; 79666; -.
DR eggNOG; KOG1729; Eukaryota.
DR GeneTree; ENSGT00940000156408; -.
DR HOGENOM; CLU_064864_1_0_1; -.
DR OMA; PVRVCEH; -.
DR OrthoDB; 5385125at2759; -.
DR TreeFam; TF315235; -.
DR Proteomes; UP000008225; Chromosome 16.
DR Bgee; ENSCJAG00000047758; Expressed in kidney and 6 other cell types or tissues.
DR GO; GO:0030133; C:transport vesicle; IEA:Ensembl.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15755; FYVE_PKHF2; 1.
DR CDD; cd01218; PH_Phafin2-like; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR037871; PH_Phafin.
DR InterPro; IPR047966; PLEKHF2_FYVE.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46280:SF1; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 2; 1.
DR PANTHER; PTHR46280; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 2-RELATED; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00064; FYVE; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 2: Evidence at transcript level;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 35..131
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 152..212
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 221..249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..235
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 249 AA; 27842 MW; F5E3F845881F5246 CRC64;
MVDRLANSEA NTRRISIVEN CFGAAGQPLT IPGRVLIGEG VLTKLCRKKP KARQFFLFND
ILVYGNIVIQ KKKYNKQHII PLENVTIDSI KDEGDLRNGW LIKTPTKSFA VYAATATEKS
EWMNHINKCV TDLLSKSGKT PSNEHAAVWV PDSEATVCMR CQKAKFTPVN RRHHCRKCGF
VVCGPCSEKR FLLPSQSSKP VRICDFCYDL LSTGDMATCQ PARSDSYSQS LKSPLNDMSD
DDEDDDSSD
//
