ID F7FQW8_MONDO Unreviewed; 914 AA.
AC F7FQW8;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=Nuclear pore complex protein {ECO:0000256|RuleBase:RU365072};
GN Name=NUP107 {ECO:0000313|Ensembl:ENSMODP00000009005.4};
OS Monodelphis domestica (Gray short-tailed opossum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Didelphimorphia; Didelphidae; Monodelphis.
OX NCBI_TaxID=13616 {ECO:0000313|Ensembl:ENSMODP00000009005.4, ECO:0000313|Proteomes:UP000002280};
RN [1] {ECO:0000313|Ensembl:ENSMODP00000009005.4, ECO:0000313|Proteomes:UP000002280}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=17495919; DOI=10.1038/nature05805;
RA Mikkelsen T.S., Wakefield M.J., Aken B., Amemiya C.T., Chang J.L., Duke S.,
RA Garber M., Gentles A.J., Goodstadt L., Heger A., Jurka J., Kamal M.,
RA Mauceli E., Searle S.M., Sharpe T., Baker M.L., Batzer M.A., Benos P.V.,
RA Belov K., Clamp M., Cook A., Cuff J., Das R., Davidow L., Deakin J.E.,
RA Fazzari M.J., Glass J.L., Grabherr M., Greally J.M., Gu W., Hore T.A.,
RA Huttley G.A., Kleber M., Jirtle R.L., Koina E., Lee J.T., Mahony S.,
RA Marra M.A., Miller R.D., Nicholls R.D., Oda M., Papenfuss A.T., Parra Z.E.,
RA Pollock D.D., Ray D.A., Schein J.E., Speed T.P., Thompson K.,
RA VandeBerg J.L., Wade C.M., Walker J.A., Waters P.D., Webber C.,
RA Weidman J.R., Xie X., Zody M.C., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Bloom T., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., MacCallum I., Graves J.A., Ponting C.P., Breen M.,
RA Samollow P.B., Lander E.S., Lindblad-Toh K.;
RT "Genome of the marsupial Monodelphis domestica reveals innovation in non-
RT coding sequences.";
RL Nature 447:167-177(2007).
RN [2] {ECO:0000313|Ensembl:ENSMODP00000009005.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Functions as a component of the nuclear pore complex (NPC).
CC {ECO:0000256|RuleBase:RU365072}.
CC -!- SUBUNIT: Part of the nuclear pore complex (NPC).
CC {ECO:0000256|RuleBase:RU365072}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nuclear pore complex
CC {ECO:0000256|RuleBase:RU365072}. Nucleus membrane
CC {ECO:0000256|RuleBase:RU365072}.
CC -!- SIMILARITY: Belongs to the nucleoporin Nup84/Nup107 family.
CC {ECO:0000256|ARBA:ARBA00009510, ECO:0000256|RuleBase:RU365072}.
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DR RefSeq; XP_007502948.1; XM_007502886.2.
DR RefSeq; XP_007502949.1; XM_007502887.2.
DR AlphaFoldDB; F7FQW8; -.
DR STRING; 13616.ENSMODP00000009005; -.
DR Ensembl; ENSMODT00000009182.4; ENSMODP00000009005.4; ENSMODG00000007267.4.
DR GeneID; 100021491; -.
DR CTD; 57122; -.
DR eggNOG; KOG1964; Eukaryota.
DR GeneTree; ENSGT00390000012080; -.
DR HOGENOM; CLU_012944_1_0_1; -.
DR InParanoid; F7FQW8; -.
DR OMA; YKVYTKH; -.
DR OrthoDB; 2718743at2759; -.
DR TreeFam; TF324259; -.
DR Proteomes; UP000002280; Chromosome 8.
DR Bgee; ENSMODG00000007267; Expressed in spermatid and 20 other cell types or tissues.
DR GO; GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0031080; C:nuclear pore outer ring; IBA:GO_Central.
DR GO; GO:0017056; F:structural constituent of nuclear pore; IBA:GO_Central.
DR GO; GO:0006406; P:mRNA export from nucleus; IBA:GO_Central.
DR GO; GO:0000973; P:post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery; IBA:GO_Central.
DR GO; GO:0006606; P:protein import into nucleus; IBA:GO_Central.
DR Gene3D; 1.10.3450.20; -; 1.
DR Gene3D; 1.20.190.50; -; 1.
DR InterPro; IPR007252; Nup84/Nup107.
DR PANTHER; PTHR13003:SF2; NUCLEAR PORE COMPLEX PROTEIN NUP107; 1.
DR PANTHER; PTHR13003; NUP107-RELATED; 1.
DR Pfam; PF04121; Nup84_Nup100; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|RuleBase:RU365072};
KW mRNA transport {ECO:0000256|ARBA:ARBA00022816};
KW Nuclear pore complex {ECO:0000256|RuleBase:RU365072};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU365072};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000002280};
KW Translocation {ECO:0000256|ARBA:ARBA00023010,
KW ECO:0000256|RuleBase:RU365072};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365072}.
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 637..656
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 914 AA; 105018 MW; A2BD37C5422DCBFA CRC64;
MASPMVRDVE VTRTARRQSA HKRVSILTPQ EDILANATPR NQMIPRTPNS HCQTLFRSLL
RQPDVSAILA TGTKSPRLAP LSTSLGNLPM TTNLDESNWT ANFSPQRSGI FANNEPSNMT
EDVTLSAVML REDDPGEAAT MSMYSDFLHT FLKHASNTVF ELIEEYENIC ESQVNILSKI
ASRATPGLQK FSKTASVLWL LQQEMVTWRL LASLYKDRIQ SVLEEENAFA IASLNASEKT
VVDTLFQRDS LIRQSQLVVD WLESIAKDDI GDFSDNIEFY AKSVYWENTL HTLKQRQLIS
FIGSVRPLVT ELDPDAPIRQ KMPLDDLDRE DDNRLLKYLF TLIRSGMTDE AQRLCKRCGQ
AWRAATLEGW KLYHDPNVNG GTELEPVEGN PYRCIWKISC WRMAEDELFN KYERAIYAAL
SGNLKQLLPV CETWEDTVWA YFRVMVDSLV EQEVRTSVVT LDETEELPRE HLEANWTLEK
VFEELQATDK KRVLEENQEH YHVIQKFLIL GDIDGMMEEF LKWLSKGKNL LPGHLLRFMT
HLVLFFRTLG IQIKEEVSVQ VLKAYIQLLI CEKHANLIAF YTSHLPQDLA VAQYAAFLEG
VTEFEQRHRC LELAKEAGLD VATITKTVVE NTRRKDAGDF SHHDTAPSLD TGTTEEDRSK
IDVIDWLVFD PAQRAEALKQ GNAIMRKFLA SKKHEAAKEV FAKIPQDCIA EIYNQWEENG
MDTPLPAEDD NAIREHLCIR AYLEAHETFN EWFKHMNSAP QKPTLLPQSS FTEKVAHEHK
EKKYEMDFGI WKGHLDALTA EVKEKMYNVL LFVDGGWMVD VREDAEDDPE RTHQMALLRR
LCLPMLCFLL HTILHSTNQF QECLQLADMV SSERHKLYTV FSKEELRKLL QKLRESSLML
LDQGLDPLGY ESSS
//
