ID F7FRW5_MACMU Unreviewed; 222 AA.
AC F7FRW5;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Transmembrane 9 superfamily member 1 {ECO:0000313|Ensembl:ENSMMUP00000033050.3};
GN Name=CHMP4A {ECO:0000313|Ensembl:ENSMMUP00000033050.3};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|Ensembl:ENSMMUP00000033050.3, ECO:0000313|Proteomes:UP000006718};
RN [1] {ECO:0000313|Proteomes:UP000006718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=17573 {ECO:0000313|Proteomes:UP000006718};
RX PubMed=17431167; DOI=10.1126/science.1139247;
RA Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M.,
RA Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., Wilson R.K.,
RA Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., Hardison R.C.,
RA Makova K.D., Miller W., Milosavljevic A., Palermo R.E., Siepel A.,
RA Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J.,
RA Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., Dinh H.H.,
RA Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., Godfrey J.,
RA Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N.,
RA Joshi V., Khan Z.M., Kirkness E.F., Cree A., Fowler R.G., Lee S.,
RA Lewis L.R., Li Z., Liu Y.-S., Moore S.M., Muzny D., Nazareth L.V.,
RA Ngo D.N., Okwuonu G.O., Pai G., Parker D., Paul H.A., Pfannkoch C.,
RA Pohl C.S., Rogers Y.-H.C., Ruiz S.J., Sabo A., Santibanez J.,
RA Schneider B.W., Smith S.M., Sodergren E., Svatek A.F., Utterback T.R.,
RA Vattathil S., Warren W., White C.S., Chinwalla A.T., Feng Y., Halpern A.L.,
RA Hillier L.W., Huang X., Minx P., Nelson J.O., Pepin K.H., Qin X.,
RA Sutton G.G., Venter E., Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P.,
RA Jones S.M., Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L.,
RA Csuros M., Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H.,
RA Liu Y., Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E.,
RA Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J.,
RA Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J.,
RA Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A.,
RA Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., Denby A.,
RA Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., Marklein A.,
RA Nielsen R., Vallender E.J., Clark A.G., Ferguson B., Hernandez R.D.,
RA Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., Pu L.-L., Ren Y.,
RA Smith D.G., Wheeler D.A., Schenck I., Ball E.V., Chen R., Cooper D.N.,
RA Giardine B., Hsu F., Kent W.J., Lesk A., Nelson D.L., O'brien W.E.,
RA Pruefer K., Stenson P.D., Wallace J.C., Ke H., Liu X.-M., Wang P.,
RA Xiang A.P., Yang F., Barber G.P., Haussler D., Karolchik D., Kern A.D.,
RA Kuhn R.M., Smith K.E., Zwieg A.S.;
RT "Evolutionary and biomedical insights from the rhesus macaque genome.";
RL Science 316:222-234(2007).
RN [2] {ECO:0000313|Ensembl:ENSMMUP00000033050.3}
RP IDENTIFICATION.
RC STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000033050.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SNF7 family.
CC {ECO:0000256|ARBA:ARBA00006190}.
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DR AlphaFoldDB; F7FRW5; -.
DR SMR; F7FRW5; -.
DR PaxDb; 9544-ENSMMUP00000033049; -.
DR Ensembl; ENSMMUT00000039985.3; ENSMMUP00000033050.3; ENSMMUG00000012493.4.
DR VEuPathDB; HostDB:ENSMMUG00000012493; -.
DR GeneTree; ENSGT00940000158667; -.
DR HOGENOM; CLU_071097_0_0_1; -.
DR OrthoDB; 5360005at2759; -.
DR Proteomes; UP000006718; Chromosome 7.
DR Bgee; ENSMMUG00000012493; Expressed in fibroblast and 21 other cell types or tissues.
DR ExpressionAtlas; F7FRW5; baseline.
DR GO; GO:1904930; C:amphisome membrane; IEA:UniProt.
DR GO; GO:0000776; C:kinetochore; IEA:UniProt.
DR GO; GO:0005828; C:kinetochore microtubule; IEA:UniProt.
DR GO; GO:0005765; C:lysosomal membrane; IEA:UniProt.
DR GO; GO:0030496; C:midbody; IEA:UniProt.
DR GO; GO:0032585; C:multivesicular body membrane; IEA:UniProt.
DR GO; GO:0005643; C:nuclear pore; IEA:UniProt.
DR GO; GO:0097352; P:autophagosome maturation; IEA:UniProt.
DR GO; GO:1902774; P:late endosome to lysosome transport; IEA:UniProt.
DR GO; GO:0061952; P:midbody abscission; IEA:UniProt.
DR GO; GO:0007080; P:mitotic metaphase chromosome alignment; IEA:UniProt.
DR GO; GO:0071985; P:multivesicular body sorting pathway; IEA:UniProt.
DR GO; GO:0031468; P:nuclear membrane reassembly; IEA:UniProt.
DR GO; GO:0001778; P:plasma membrane repair; IEA:UniProt.
DR GO; GO:1901673; P:regulation of mitotic spindle assembly; IEA:UniProt.
DR GO; GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IEA:UniProt.
DR GO; GO:0046761; P:viral budding from plasma membrane; IEA:UniProt.
DR GO; GO:0039702; P:viral budding via host ESCRT complex; IEA:UniProt.
DR Gene3D; 6.10.250.1710; -; 1.
DR Gene3D; 1.10.287.1060; ESAT-6-like; 1.
DR InterPro; IPR005024; Snf7_fam.
DR PANTHER; PTHR22761; CHARGED MULTIVESICULAR BODY PROTEIN; 1.
DR PANTHER; PTHR22761:SF14; CHARGED MULTIVESICULAR BODY PROTEIN 4A; 1.
DR Pfam; PF03357; Snf7; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006718}.
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 176..222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 222 AA; 25079 MW; 34F46AE8A1E5F5EB CRC64;
MSGLGRLFGK GKKEKGPTPE EAIQKLKETE KILIKKQEFL EQKIQQELQT AKKYGTKNKR
AALQALRRKK RFEQQLAQTD GTLSTLEFQR EAIENATTNA EVLRTMELAA QGMKKAYQDM
DIDKVDELMT DITEQQEVAQ QISDAISRPM GFGDDVDEDE LLEELELLEQ EELAQELLSV
GDKEEEPPVK LPSVPSTHLP AEPAPKADED EEALKQLAEW VS
//
