GenomeNet

Database: UniProt
Entry: F7FWL7_MACMU
LinkDB: F7FWL7_MACMU
Original site: F7FWL7_MACMU 
ID   F7FWL7_MACMU            Unreviewed;       461 AA.
AC   F7FWL7; G7NLW2;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 2.
DT   05-JUN-2019, entry version 57.
DE   SubName: Full=Cyclic AMP-responsive element-binding protein 3-like protein 3 {ECO:0000313|EMBL:EHH29483.1};
GN   Name=CREB3L3 {ECO:0000313|Ensembl:ENSMMUP00000026237};
GN   ORFNames=EGK_09929 {ECO:0000313|EMBL:EHH29483.1};
OS   Macaca mulatta (Rhesus macaque).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9544 {ECO:0000313|Ensembl:ENSMMUP00000026237, ECO:0000313|Proteomes:UP000006718};
RN   [1] {ECO:0000313|Ensembl:ENSMMUP00000026237, ECO:0000313|Proteomes:UP000006718}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000026237,
RC   ECO:0000313|Proteomes:UP000006718};
RX   PubMed=17431167; DOI=10.1126/science.1139247;
RA   Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M.,
RA   Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C.,
RA   Wilson R.K., Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W.,
RA   Hardison R.C., Makova K.D., Miller W., Milosavljevic A., Palermo R.E.,
RA   Siepel A., Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J.,
RA   Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y.,
RA   Dinh H.H., Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T.,
RA   Godfrey J., Hawes A.C., Hernandez J., Hines S., Holder M., Hume J.,
RA   Jhangiani S.N., Joshi V., Khan Z.M., Kirkness E.F., Cree A.,
RA   Fowler R.G., Lee S., Lewis L.R., Li Z., Liu Y.-S., Moore S.M.,
RA   Muzny D., Nazareth L.V., Ngo D.N., Okwuonu G.O., Pai G., Parker D.,
RA   Paul H.A., Pfannkoch C., Pohl C.S., Rogers Y.-H.C., Ruiz S.J.,
RA   Sabo A., Santibanez J., Schneider B.W., Smith S.M., Sodergren E.,
RA   Svatek A.F., Utterback T.R., Vattathil S., Warren W., White C.S.,
RA   Chinwalla A.T., Feng Y., Halpern A.L., Hillier L.W., Huang X.,
RA   Minx P., Nelson J.O., Pepin K.H., Qin X., Sutton G.G., Venter E.,
RA   Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P., Jones S.M.,
RA   Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L., Csuros M.,
RA   Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H., Liu Y.,
RA   Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E.,
RA   Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J.,
RA   Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J.,
RA   Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A.,
RA   Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J.,
RA   Denby A., Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A.,
RA   Marklein A., Nielsen R., Vallender E.J., Clark A.G., Ferguson B.,
RA   Hernandez R.D., Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S.,
RA   Pu L.-L., Ren Y., Smith D.G., Wheeler D.A., Schenck I., Ball E.V.,
RA   Chen R., Cooper D.N., Giardine B., Hsu F., Kent W.J., Lesk A.,
RA   Nelson D.L., O'brien W.E., Pruefer K., Stenson P.D., Wallace J.C.,
RA   Ke H., Liu X.-M., Wang P., Xiang A.P., Yang F., Barber G.P.,
RA   Haussler D., Karolchik D., Kern A.D., Kuhn R.M., Smith K.E.,
RA   Zwieg A.S.;
RT   "Evolutionary and biomedical insights from the rhesus macaque
RT   genome.";
RL   Science 316:222-234(2007).
RN   [2] {ECO:0000313|EMBL:EHH29483.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CR-5 {ECO:0000313|EMBL:EHH29483.1};
RX   PubMed=22002653; DOI=10.1038/nbt.1992;
RA   Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N.,
RA   Li Q., Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P.,
RA   Huang Z., Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T.,
RA   Huang Y., Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D.,
RA   Li B., Liu X., Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X.,
RA   Li Y., Wang W., Katze M.G., Su B., Nielsen R., Yang H., Wang J.,
RA   Wang X., Wang J.;
RT   "Genome sequencing and comparison of two nonhuman primate animal
RT   models, the cynomolgus and Chinese rhesus macaques.";
RL   Nat. Biotechnol. 29:1019-1023(2011).
RN   [3] {ECO:0000313|Ensembl:ENSMMUP00000026237}
RP   IDENTIFICATION.
RC   STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000026237};
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; JSUE03020328; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; JSUE03020329; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; JSUE03020330; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; JSUE03020331; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; JSUE03020332; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CM001271; EHH29483.1; -; Genomic_DNA.
DR   STRING; 9544.ENSMMUP00000026237; -.
DR   Ensembl; ENSMMUT00000028043; ENSMMUP00000026237; ENSMMUG00000019954.
DR   eggNOG; KOG0709; Eukaryota.
DR   eggNOG; ENOG410ZZQM; LUCA.
DR   GeneTree; ENSGT00940000159261; -.
DR   InParanoid; F7FWL7; -.
DR   TreeFam; TF316079; -.
DR   Proteomes; UP000006718; Chromosome 19.
DR   Bgee; ENSMMUG00000019954; Expressed in 10 organ(s), highest expression level in liver.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:Ensembl.
DR   GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR   GO; GO:0035497; F:cAMP response element binding; IEA:InterPro.
DR   GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:Ensembl.
DR   GO; GO:0046982; F:protein heterodimerization activity; IEA:Ensembl.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IEA:InterPro.
DR   GO; GO:1990440; P:positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress; IEA:Ensembl.
DR   InterPro; IPR004827; bZIP.
DR   InterPro; IPR029806; CREBH.
DR   PANTHER; PTHR45996:SF1; PTHR45996:SF1; 1.
DR   Pfam; PF00170; bZIP_1; 1.
DR   SMART; SM00338; BRLZ; 1.
DR   PROSITE; PS50217; BZIP; 1.
DR   PROSITE; PS00036; BZIP_BASIC; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006718};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006718}.
FT   DOMAIN      243    306       BZIP. {ECO:0000259|PROSITE:PS50217}.
FT   REGION       49    122       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F7FWL7}.
FT   REGION      369    405       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F7FWL7}.
FT   COILED      268    309       {ECO:0000256|SAM:Coils}.
FT   COMPBIAS     69     84       Polar. {ECO:0000256|MobiDB-lite:F7FWL7}.
SQ   SEQUENCE   461 AA;  49397 MW;  4F928E7060083560 CRC64;
     MNMDLAAGKM ACSACPMDPI DSFELLDLLF DRQDGILRHV ELGDDWGHVK DQQVQPNPDP
     DDFLSSILGS GDSLPSSPLW SPEGSDSGIS EDLPSDPQDT PPRSGPATSP AGCHPAQPGK
     GPCLSYHPGN SCPTTPPGPV VQVPEASVTI DLEMWSPGGR TYAEKQADPV HVPPRCNLTV
     KDLLLSGSSG DLQQHHLGVS HLLRPGAEHC QELVLTEDEK KLLAKEGITL PTQLPLTKYE
     ERVLKKIRRK IRNKQSAQES RKKKKEYIDG LETRMSACTA QNQELQRKVL HLEKQNLSLL
     EQLKKLQAIV VQSTSKSAQT GTCVAVLLLS FALIILPSIS PFGPNKAESP GDFAPVRVFS
     RTLHNDAASR VTSDAVPGSE APGPQPEADT TQEGSPGIPG ADWDFRDSAN LTNSTEEVDN
     ATLILRNATE GLGQVTLLDW VAPGPSTGSG RAGLEAAGDE L
//
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