ID F7GJ54_CALJA Unreviewed; 361 AA.
AC F7GJ54;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Inducible T cell costimulator ligand {ECO:0000313|Ensembl:ENSCJAP00000006492.4};
GN Name=ICOSLG {ECO:0000313|Ensembl:ENSCJAP00000006492.4};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000006492.4, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000006492.4}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000006492.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F7GJ54; -.
DR STRING; 9483.ENSCJAP00000006492; -.
DR Ensembl; ENSCJAT00000006856.5; ENSCJAP00000006492.4; ENSCJAG00000003576.5.
DR eggNOG; ENOG502SQ2A; Eukaryota.
DR GeneTree; ENSGT00940000161590; -.
DR HOGENOM; CLU_013137_8_2_1; -.
DR InParanoid; F7GJ54; -.
DR OMA; QELTFTC; -.
DR OrthoDB; 5349267at2759; -.
DR TreeFam; TF331083; -.
DR Proteomes; UP000008225; Chromosome 21.
DR Bgee; ENSCJAG00000003576; Expressed in kidney and 4 other cell types or tissues.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR24100; BUTYROPHILIN; 1.
DR PANTHER; PTHR24100:SF55; ICOS LIGAND-RELATED; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..361
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5023861166"
FT TRANSMEM 252..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 6..126
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 138..224
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 309..361
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 335..351
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 361 AA; 39184 MW; 8D2C44B5BC9F79F1 CRC64;
MRLSSPGLLF LLLSSLRAET QEKEVRAMVG SDVELSCASP EGSRFDLNDI YVYWQISDTV
VAYHVPQNSS SSVASRYRNR AAMSPSGMLH GDFSLRLFNV TPDDEQKFRC VVLSKSLGFQ
TVLEVVVTLH VAANFSMPVV SAPHSPSQDE LTFTCMSVNG YPRPRVYWIN KTDNSLLDQA
LQNDTIVLNA QGLYNVVSVL RIAATPSVNI GCCIENALLQ QNLTVGSQTE NHIGGRDNIT
KDTDSTPEAK NVAVWSALAV PCLLVALAMW VYRCRRPCRG YAGVWAARPE PELTGHVCPS
SPPRSVIRTK GKCPQVSGLA TVTGSHPQEG PGDGLLSTRS RQDSAPGSSQ HPDPLGTRAF
P
//
