ID F7GKM7_MACMU Unreviewed; 704 AA.
AC F7GKM7;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Asteroid homolog 1 {ECO:0000313|Ensembl:ENSMMUP00000038439.2};
GN Name=ASTE1 {ECO:0000313|Ensembl:ENSMMUP00000038439.2,
GN ECO:0000313|VGNC:VGNC:84874};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|Ensembl:ENSMMUP00000038439.2, ECO:0000313|Proteomes:UP000006718};
RN [1] {ECO:0000313|Proteomes:UP000006718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=17573 {ECO:0000313|Proteomes:UP000006718};
RX PubMed=17431167; DOI=10.1126/science.1139247;
RA Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M.,
RA Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., Wilson R.K.,
RA Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., Hardison R.C.,
RA Makova K.D., Miller W., Milosavljevic A., Palermo R.E., Siepel A.,
RA Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J.,
RA Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., Dinh H.H.,
RA Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., Godfrey J.,
RA Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N.,
RA Joshi V., Khan Z.M., Kirkness E.F., Cree A., Fowler R.G., Lee S.,
RA Lewis L.R., Li Z., Liu Y.-S., Moore S.M., Muzny D., Nazareth L.V.,
RA Ngo D.N., Okwuonu G.O., Pai G., Parker D., Paul H.A., Pfannkoch C.,
RA Pohl C.S., Rogers Y.-H.C., Ruiz S.J., Sabo A., Santibanez J.,
RA Schneider B.W., Smith S.M., Sodergren E., Svatek A.F., Utterback T.R.,
RA Vattathil S., Warren W., White C.S., Chinwalla A.T., Feng Y., Halpern A.L.,
RA Hillier L.W., Huang X., Minx P., Nelson J.O., Pepin K.H., Qin X.,
RA Sutton G.G., Venter E., Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P.,
RA Jones S.M., Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L.,
RA Csuros M., Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H.,
RA Liu Y., Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E.,
RA Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J.,
RA Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J.,
RA Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A.,
RA Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., Denby A.,
RA Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., Marklein A.,
RA Nielsen R., Vallender E.J., Clark A.G., Ferguson B., Hernandez R.D.,
RA Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., Pu L.-L., Ren Y.,
RA Smith D.G., Wheeler D.A., Schenck I., Ball E.V., Chen R., Cooper D.N.,
RA Giardine B., Hsu F., Kent W.J., Lesk A., Nelson D.L., O'brien W.E.,
RA Pruefer K., Stenson P.D., Wallace J.C., Ke H., Liu X.-M., Wang P.,
RA Xiang A.P., Yang F., Barber G.P., Haussler D., Karolchik D., Kern A.D.,
RA Kuhn R.M., Smith K.E., Zwieg A.S.;
RT "Evolutionary and biomedical insights from the rhesus macaque genome.";
RL Science 316:222-234(2007).
RN [2] {ECO:0000313|Ensembl:ENSMMUP00000038439.2}
RP IDENTIFICATION.
RC STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000038439.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the asteroid family.
CC {ECO:0000256|ARBA:ARBA00007398}.
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DR AlphaFoldDB; F7GKM7; -.
DR STRING; 9544.ENSMMUP00000038439; -.
DR PaxDb; 9544-ENSMMUP00000038439; -.
DR Ensembl; ENSMMUT00000045411.3; ENSMMUP00000038439.2; ENSMMUG00000005142.4.
DR VEuPathDB; HostDB:ENSMMUG00000005142; -.
DR VGNC; VGNC:84874; ASTE1.
DR eggNOG; ENOG502QQRA; Eukaryota.
DR GeneTree; ENSGT00390000010145; -.
DR InParanoid; F7GKM7; -.
DR OMA; AHQWNCP; -.
DR TreeFam; TF324582; -.
DR Proteomes; UP000006718; Chromosome 2.
DR Bgee; ENSMMUG00000005142; Expressed in ileum and 23 other cell types or tissues.
DR ExpressionAtlas; F7GKM7; baseline.
DR GO; GO:0004518; F:nuclease activity; IEA:InterPro.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR InterPro; IPR026832; Asteroid.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR InterPro; IPR006085; XPG_DNA_repair_N.
DR PANTHER; PTHR15665; ASTEROID PROTEIN; 1.
DR PANTHER; PTHR15665:SF1; PROTEIN ASTEROID HOMOLOG 1; 1.
DR Pfam; PF00752; XPG_N; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006718}.
FT DOMAIN 1..97
FT /note="XPG N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00752"
FT REGION 646..670
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 704 AA; 79946 MW; D733650D5075E016 CRC64;
MGIRGLMSFV EDHSNEFFTD LKLRDTKIVI DGYALFHRLS FNSNLELRYG GDYDSFADIV
QNFFESLFAC NICPYVVLDG GCDISDKKLT TLKDRAREKI QMAHSLSVGG SGYVCPLLIR
EVFIQVLIKL QVCFVQCFSE ADRDIMTLAN HWNCPVLSSD SDFCIFDLKT GFCPLNSFQW
RNINTIKGTQ NYIPAKCFSL DAFCHHFSNM NKALLPLFAV LCGNDHINLP IMETFLSKAR
LPLGATSSKG RRHHRILGLL NWLSHFANPT EALDNVLKYL PKKDRENVKE LLCGSMEEYQ
QSRVKLQDFF QCGTYACPDA LNLGLPEWVL VALAKGQLSP FISDALVLRR TILHTQVENM
QQPNAHRISQ PIRQIIYGLL LNASPHLDKT SRNALPPQPL AFSEMERINK NIKTSIIDAV
ELAKDHSDLS KLTELSLRRR QMLLLETLKV KQTILEPIPA SLKLPVAVSC YWLQHTETKT
KLHHLQSLLL AMLMGPLTAI INSPGKEELQ EDGAKMLYAE FQRVKVQTRL GTRLDLDTAH
IFCQWQSCLQ MGMYLNQLLS TPLPEPDLTR PSAFNTLNED IWRHTKYGGT LYISRLYSGS
LVHGLCQQLL ASTSVESLLS MCPEAKQLYE HLFNATRSYA PTEIFLPKGK SNSKKKRQKK
QNTSCSKNRG RTTAHTKCWY KGNNRFGLLM VENLEEHSEA SDLE
//
