ID F7GM30_CALJA Unreviewed; 1380 AA.
AC F7GM30;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 3.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=Sushi, nidogen and EGF like domains 1 {ECO:0000313|Ensembl:ENSCJAP00000011720.3};
GN Name=SNED1 {ECO:0000313|Ensembl:ENSCJAP00000011720.3};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000011720.3, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000011720.3}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000011720.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR Ensembl; ENSCJAT00000012363.3; ENSCJAP00000011720.3; ENSCJAG00000006352.5.
DR eggNOG; KOG1217; Eukaryota.
DR eggNOG; KOG4291; Eukaryota.
DR GeneTree; ENSGT00940000160730; -.
DR HOGENOM; CLU_005107_0_0_1; -.
DR Proteomes; UP000008225; Chromosome 6.
DR Bgee; ENSCJAG00000006352; Expressed in ovary and 6 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
DR CDD; cd00033; CCP; 1.
DR CDD; cd00054; EGF_CA; 14.
DR CDD; cd00063; FN3; 3.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 2.10.25.10; Laminin; 15.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003886; NIDO_dom.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR12916; CYTOCHROME C OXIDASE POLYPEPTIDE VIC-2; 1.
DR PANTHER; PTHR12916:SF4; NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1-RELATED; 1.
DR Pfam; PF00008; EGF; 12.
DR Pfam; PF00041; fn3; 3.
DR Pfam; PF12661; hEGF; 2.
DR Pfam; PF06119; NIDO; 1.
DR PRINTS; PR00010; EGFBLOOD.
DR SMART; SM00032; CCP; 1.
DR SMART; SM00181; EGF; 15.
DR SMART; SM00179; EGF_CA; 14.
DR SMART; SM00060; FN3; 3.
DR SMART; SM00539; NIDO; 1.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 12.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 4.
DR PROSITE; PS00022; EGF_1; 15.
DR PROSITE; PS01186; EGF_2; 13.
DR PROSITE; PS50026; EGF_3; 15.
DR PROSITE; PS01187; EGF_CA; 1.
DR PROSITE; PS50853; FN3; 3.
DR PROSITE; PS51220; NIDO; 1.
DR PROSITE; PS50923; SUSHI; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Sushi {ECO:0000256|ARBA:ARBA00022659, ECO:0000256|PROSITE-
KW ProRule:PRU00302}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..1380
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5035247415"
FT DOMAIN 103..258
FT /note="NIDO"
FT /evidence="ECO:0000259|PROSITE:PS51220"
FT DOMAIN 268..309
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 311..347
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 349..385
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 387..423
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 429..465
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 468..500
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 541..577
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 580..616
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 619..655
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 657..693
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 696..753
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 753..789
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 791..827
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 829..865
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 867..903
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 908..1006
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1007..1105
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1106..1200
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1274..1310
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REGION 1201..1222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1358..1380
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 299..308
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 337..346
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 375..384
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 413..422
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 455..464
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 490..499
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 567..576
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 606..615
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 645..654
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 683..692
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 724..751
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 779..788
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 817..826
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 855..864
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 893..902
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1300..1309
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 1380 AA; 148209 MW; 8585404BA6031302 CRC64;
MRLGVAWALL AAAALGLGAR GVRGAVALAD FYPFGAERGD AVTPKQDDGG SGLRPLSGPF
PFFGARHSGL FVNNNGIISF LKEVSQFTPV AFPIAKDRCV VAAFWADVDN RRAGDVYYRE
ATDPATLRRA TEDVRRYFPE LPDFSATWVF VATWYRVTFF GGSSSSPVNT FQTVLITDGK
LSFTIFNYES ITWTTGTHAS SGGNATGLGG IAAQAGFNAG DGQRYFSIPG SRTADMADVE
TTTNVGVPGR WAFRIDDAQV RVGGCAHTTS VCLALRPCLN GGKCIEDCVT GNPSYTCSCL
SGFTGRRCHL DVNECASQPC QNGGTCAHGI NSFSCQCPAG FGGPTCETAQ SPCDTKECHN
GGQCQVERGS AVCMCQAGYT GAACETDVDD CSSEPCLNGG SCVDLMGNYT CLCAEPFTGP
HCETGHHSVP DACLSAPCHN GGTCVEADQG YVCECPEGFM GLDCRERISN GCECRNGGRC
LGTNTTLCQC PPGFFGLLCE FEITAMPCNM NTQCPDGGYC MEHGGRYLCV CHTDHNASHS
LPSPCDSDPC FNGGSCDAHG DSYTCECPRG FHGKHCEKAR PHLCSSGPCR NGGTCKEAGS
EYHCSCPYRF TGRHCEIGKP DSCASGPCHN GGTCFHYIGK YKCDCPPGFS GRHCEIAPSP
CFRSPCVNGG TCEDRGVDFF CHCQAGYMGH RCQAEVDCGP PEEVKHATLR FDSTRLGAVA
LYACDRGYSL STPIRIRVCQ PQGVWSEPPQ CLEIDECRSQ PCLHGGSCQD RVAGYLCLCS
AGYDGAHCEL ERDECRAQPC RNGGSCRNLP GTFVCQCPAG FAGVRCETEV DACNSSPCQH
GGRCESGGGA YLCVCPEGFF GYHCETVSDP CFSSPCGGRG YCLVTNGSHS CTCKVGYTGK
DCAKELFPPT ALKMDRVEES GVSISWNPPD GPAARQMLDG YAVTYVSSDG AYRRTDFVDR
SRSSHQLRAL AAGRAYNISI FSVKRNTNNK NDISRPAVLL VHTRPRPVDG FEVTNVTAST
ISVQWALHRI HHATVSGVRV SIRHPEALGD QATDVDRSVD RFTFGALLPG RRYTIQLTTL
SGLRGEEHPT ESLATAPTHV WTRPLPPANL TATRVTATSA HVVWDAPTPG SLLEAYVINV
TTSQSAKSRY VPSGKLASYT LRDLLPGQRY QLSVTAVQST EQGPLHSEPA HLYIITSPSD
GTDRRWHQGG HHPRMLSNRP PPARLPELRL LNDHSVLETP TQPPRFSELV DGRGRVSARF
SGSPSKAATV RSHAPGNCSE NPCQNGGTCI PGTDAHSCDC GPGFKGRRCE LACIKVSRPC
TRLFSETKSF PVWEGGVCHH VYKRVYRVHQ DICFKESCES TSSKKAPNRK QSKSQTLEKS
//
