ID F7GXS0_CALJA Unreviewed; 770 AA.
AC F7GXS0;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 3.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Kirre like nephrin family adhesion molecule 1 {ECO:0000313|Ensembl:ENSCJAP00000012541.4};
GN Name=KIRREL1 {ECO:0000313|Ensembl:ENSCJAP00000012541.4};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000012541.4, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000012541.4}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000012541.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily.
CC {ECO:0000256|ARBA:ARBA00008637}.
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DR AlphaFoldDB; F7GXS0; -.
DR Ensembl; ENSCJAT00000013218.5; ENSCJAP00000012541.4; ENSCJAG00000006686.5.
DR eggNOG; KOG3510; Eukaryota.
DR GeneTree; ENSGT00940000155795; -.
DR OrthoDB; 5362512at2759; -.
DR TreeFam; TF327139; -.
DR Proteomes; UP000008225; Chromosome 18.
DR Bgee; ENSCJAG00000006686; Expressed in ovary and 5 other cell types or tissues.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR CDD; cd00096; Ig; 1.
DR CDD; cd05759; IgI_2_KIRREL3-like; 1.
DR CDD; cd05898; IgI_5_KIRREL3; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR11640:SF14; KIN OF IRRE-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR11640; NEPHRIN; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF13927; Ig_3; 1.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 508..534
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 34..128
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 133..229
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 236..312
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 321..386
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 405..501
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 667..692
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 770 AA; 84927 MW; 5D510A454AE37F99 CRC64;
MCWFTLARVS SHNPSKQESL MWVGASFGFA GTQTRFSQEP ADQTVVAGQR AVLPCVLLNY
SGIVQWTKDG LALGMGQGLK AWPRYRVVGS ADAGQYNLEI TDAELSDDAS YECQATEAAL
RSRRAKLTVL IPPEDTRIDG GPVILLQAGT PHNLTCRAFN AKPAATIIWF RDGTQQEGAV
ASTELLKDGK RETTVSQLLI NPTDLDIGRV FTCRSMNEAI PNGKETSIEL DVHHPPTVTL
SIEPQTVQEG ERVVFTCQAT ANPEILGYRW AKGGFLIEDA HESRYETNVD YSFFTEPVSC
EVHNKVGSTN VSTLVNVHFA PRIVVDPKPT TTDIGSDVTL TCVWVGNPPL TLTWTKKDSN
MVLSNSNQLL LKSVTQADAG TYTCRAIVPR IGVAEREVPL YVNGPPIISS EAVQYAVRGD
GGKVECFIGS TPPPDRIAWA WKENFLEVGT LERYTVERTN SGSGVLSTLT INNVMEADFQ
THYNCTAWNS FGPGTAIIQL EEREVLPVGI IAGATIGAGI LLIFFFIALA FFLYRRRKGS
RKDVTLRKLD IKVETVNREP LTMHSDREDD TASVSTATRV MKAIYSSFKD DVDLKQDLRC
DTIDTREEYE MKDPTNGYYN VRAHEDRPSS RAVLYADYRA PGPARFDGRP SSRLSHSSGY
AQLNTYSRAP ASDYGPEPTP PGPAAPAGTD TTSQLSYENY EKFNSHPFPG AAGYPTYRLG
YPQAPPSGLE RTPYEAYDPI GKYATATRFS YTSQHSDYGQ RFQQRMQTHV
//
