ID F7H3U7_CALJA Unreviewed; 4561 AA.
AC F7H3U7;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 4.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Plectin {ECO:0000313|Ensembl:ENSCJAP00000039988.5};
GN Name=PLEC {ECO:0000313|Ensembl:ENSCJAP00000039988.5};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000039988.5, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000039988.5}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000039988.5}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR Ensembl; ENSCJAT00000042244.5; ENSCJAP00000039988.5; ENSCJAG00000021472.6.
DR GeneTree; ENSGT00940000159045; -.
DR Proteomes; UP000008225; Chromosome 16.
DR Bgee; ENSCJAG00000021472; Expressed in heart and 6 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0045104; P:intermediate filament cytoskeleton organization; IEA:InterPro.
DR CDD; cd21188; CH_PLEC-like_rpt1; 1.
DR CDD; cd21238; CH_PLEC_rpt2; 1.
DR CDD; cd00176; SPEC; 2.
DR Gene3D; 1.20.58.1060; -; 1.
DR Gene3D; 1.20.58.60; -; 5.
DR Gene3D; 3.30.160.780; -; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 3.90.1290.10; Plakin repeat; 6.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR041615; Desmoplakin_SH3.
DR InterPro; IPR041573; Desmoplakin_Spectrin-like.
DR InterPro; IPR049538; PCN-like_spectrin-like_rpt.
DR InterPro; IPR043197; Plakin.
DR InterPro; IPR035915; Plakin_repeat_sf.
DR InterPro; IPR001101; Plectin_repeat.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR PANTHER; PTHR23169; ENVOPLAKIN; 1.
DR PANTHER; PTHR23169:SF20; PLECTIN; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF00681; Plectin; 18.
DR Pfam; PF17902; SH3_10; 1.
DR Pfam; PF18373; Spectrin_2; 1.
DR Pfam; PF21019; Spectrin_3; 1.
DR Pfam; PF21020; Spectrin_4; 1.
DR Pfam; PF21097; SR_plectin_7; 1.
DR SMART; SM00033; CH; 2.
DR SMART; SM00250; PLEC; 33.
DR SMART; SM00150; SPEC; 6.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF75399; Plakin repeat; 7.
DR SUPFAM; SSF46966; Spectrin repeat; 5.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 42..162
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 175..280
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 818..875
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1390..1411
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1495..1521
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1671..1704
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1971..2020
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2039..2186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2641..2660
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4257..4293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4488..4561
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 672..699
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 738..794
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1112..1180
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1252..1306
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2445..2625
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1674..1704
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2075..2090
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2091..2134
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4257..4287
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4488..4554
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 4561 AA; 518403 MW; EA4CF27247B97529 CRC64;
MSQYQLRVPE PEGLGRKRTS SEDNLYLAVL RASEGKKDER DRVQKKTFTK WVNKHLIKHW
RAEAQRHISD LYEDLRDGHN LISLLEVLSG DSLPRERDVT RSSRLPREKG RMRFHKLQNV
QIALDYLRHR QVKLVNIRND DIADGNPKLT LGLIWTIILH FQISDIQVSG QSEDMTAKEK
LLLWSQRMVE GYQGLRCDNF TSSWRDGRLF NAIIHRHKPM LIDMNKVYRQ TNLENLDQAF
SVAERDLGVT RLLDPEDVDV PQPDEKSIIT YVSSLYDAMP RVPDVQDGVR ANELQLRWQE
YRELVLLLLQ WIRHHTATFE ERRFPSSFEE IEILWCQFLK FKEMELPAKE ADKNRSKGIY
QSLEGAVQAG QLKVPPGYHP LDVEKEWGKL HVAILEREKQ LRSEFERLEC LQRIVSKLQM
EAGLCEEQLN QADALLQSDV RLLAAGKVPQ RAGEVERDLD KADGMIRLLF NDVQTLKDGR
HPQGEQMYRR VYRLHERLVA IRTEYNLRLK AGVAAPAVQV TQVTLQRRPE PEDSTLRYLQ
DLLAWVEENQ HRVDGAEWGV DLPSVEAQLG SHRGLHQSIE EFRAKIERAR SDEGQLSPAT
RGAYRDCLGR LDLQYAKLLN SSKARLRSLE SLHSFVAAAT KELMWLNEKE EEEVGFDWSD
RNTNMTAKKD SYSALMRELE LKEKKIKELQ SAGDRLLRED HPARPTVESF QAALQTQWSW
MLQLCCCIEA HLKENAAYFQ FFSDVREAEE QLQKLQETLR RKYSCDRSIT VTRLEDLLQD
AQDEKEQLNE YKGHLSGLAK RAKAIVQLKP RHPAYPVRGR VPLLAVCDYK QVEVTVHKGD
ECQLVGPAQP SHWKVLSSTG SEAAVPSVCF LVPPPNQEAQ EAVTRLEAQH QALVTLWHQL
HVDMKSLLAW QSLRRDVQLI RSWSLATFRT LKPEEQRQAL HSLELHYQAF LRDSQDAGGF
GPEDRLVAER EYGSCSHHYQ QLLQSLEQGA QEESRCQRCI SELKDIRLQL EACETRTVHR
LRLPLDKEPA RECAQRIAEQ QKAQAEVEGL GKGVARLSAE AEKVLALPEP SPAAPTLRSE
LELTLGKLEQ VRSLSAIYLE KLKTISLVIR STQGAEEVLR AHEEQLKEAQ AVPATLPELE
ATKASLKKLR AQAEAQQPVF DALRDELRGA QEVGERLQQR HGERDVEVER WRERVAQLLE
RWQAILAQTD VRQRELEQLG RQLRYYRESA DPLGAWLQDA RQRQEQIQAV PLADSRAVQE
QLQQEKALLE EIERHGEKVE ECQKFAKQYI NAIKDYELQL VTYKAQLEPV ASPAKKPKVQ
SGSESVIQEY VDLRTRYSEL TTLTSQYIKF ISETLRRMEE EERLAEQQRA EERERLAEVE
AALEKQRQLA EAHAQAKAQA EREAKELQQR MQEEVVRREE AAVDAQQQKR SIQEELQQLR
QSSEAEIQAK ARQAEAAERS RLRIEEEIRV VRLQLEATER QRGGAEGELQ ALRERAEEAE
AQKRQAQEEA ERLRRQVQDE SQRKRQAEAE LALRVKAEAE AAREKQRALQ SLEELRLQAE
EAERRLRQAE VERARQVQVA LETAQRSAEA ELQSKRASFA EKTAQLERSL QEEHVAVAQL
REEAERRAQQ QAEAERAREE AERELERWQL KANEALRLRL QAEEVAQQKS LAQAEAEKQK
EEAEREARRR GKAEEQAVRQ RELAEQELEK QRQLAEGTAQ QRLAAEQELI RLRAETEQGE
QQRLLLEEEL TRLQREAAAA TQKRQELEAE LAKVRAEMEV LLASKARAEE ESRCTSEKSK
QRLEAEAGRF RELAEEAARL RALAEEAKRQ RQLAEEDAAR QRAEAERVLA EKLAAISEAT
RLKTEAEIAL KEKEAENERL RRLAEDEAFQ RRRLEEQAAQ HKADIEERLA QLRKASESEL
ERQKGLVEDT LRQRRQVEEE ILALKASFEK AAAGKAELEL ELGRIRSNAE DTLRSKEQAE
QEAARQRQLA AEEEQRRREA EERVQKSLAA EEEAARQRKA ALEEVERLKA KVEEARRLRE
RAEQESTRQL QLAQEAAQKR LQAEEKAHAF AVQQKEQELQ ETLQQEQSML DRLRSEAEAA
RRAAEEAEEA RVQAEREAAQ SRRQVEEAER LKQSAEEQAQ AQAQAQAAAE KLRKEAEQEA
TRRAQAEQAA LRQKQAADAE MEKHKKFAEQ TLRQKAQVEQ ELTTLRLQLE ETDHQKNLLD
EELQRLKAEA TEAARQRSQV EEELFSVRVQ MEELSKLKAR IEAENRALIL RDKDNTQRFL
QEEAEKMKQV AEEAARLSVA AQEAARLRQL AEEDLAQQRA LAEKMLKEKM QAVQEATRLK
AEAELLQQQK ELAQEQARRL QEDKEQMAQQ LAQETQGFQR TLEAERQRQL EMTAEAERLK
LRVAEMSRAQ ARAEEDAQCF RKQAEEIGEK LHRTELATQE KVTLVQTLEI QRQQSDHDAE
RLREAIAELE REKEKLQQEA KLLQLKSEEM QTVQQEQLLQ ETQALQQSFL SEKDSLLQRE
HFIEQEKAKL EQLFQDEVAK AQQLREEQQR QQQQMEQERQ QLVASMEEAL RRQREAEEGV
RRKQEELQRL EQQRRQQEEL LAEENQRLRE QLQRLEEEHR AALAHSEEVT ALQVAATKTL
PNGQDALDGP AVEAEPKHSF DGLRRKVPAQ RLQEAGILSA EELHRLAQGH TTVHELARRE
DVRHYLQGSS SIAGLMLKPT NEKLSIYSAL QRQLLSPGTA LILLEAQAAS GFLLDPVQNR
RLTVNEAVKE GVVGPELHHK LLSAERAVTG YTDPYTGQPI SLFQAMQKGL IVREHGIRLL
EAQIATGGVI DPVHSHRVPV DVAYQRGYFD EEMNRILADP SDDTKGFFDP NTHENLTYLQ
LLERCVEDPE TGLRLLPLTD KAAKGGELVY TDLEARDVFE KATVSAPFGK FQGKTVTIWE
IINSEYFTAE QRRDLLRQFR TGRITVEKII KIIITVVEEQ EQKGQLCFEG LRSLVPAAEL
LESSVINREL YHQLQRGERS VREVAEVDAV RRALRGAGII AGVWLEEAGQ KLSLYDALKK
DLLPSDMAVA LLEAQAGTGH IIDPSTSARL TVDEAVRAGL VGPELHEKLL SAEKAVTGYR
DPYTGQSVSL FQALKKGLIP REQGLRLLDA QLSTGGVVDP SKSHRVPMDV ACARGCLDEE
TSRALSAPRV DTKAYRNPST GEPVTYNELQ QRCRPDQLTG LSLLPLSEKA ARARQEELYS
ELQARETFEK TPVEVPVGGF KGRTVSVWEL ISSEYFTAEQ RQELLRQFRT GKVTVEKVIK
ILITIVEEVE TQRQERLSFS GLRAPVPASE LLASGVLSRA QFEQLKDGKT TVKDLSELGS
VQTLLQGSGC LAGIYLEEAK EKVSIYEAMR RGLLRPSTAA LLLEAQAATG FLVDPVRNQR
LYVHEAVKAG VVGPELHEQL LSAEKAVTGY RDPYSGSTIS LFQAMQKGLV LRQHGIRLLE
AQIATGGIID PVHSHRVPVD VAYQRGYFDQ EMNRVLADPS DDTKGFFDPN THENLTYRQL
LERCVEDPET GLRLLPLKGA EKAEVVETTQ VYTEEETRRA FEETQIDIPG GGSHGGSTMS
LWEVMQSDLI PKEQRAQLMA DFQAGRVTKE RMIIIIIEII EKTEIIRQQG LASYDYVRRR
LTAEDLYEAR IISLETYNLL REGTRSLREV LEAESAWRYL YGTGCVAGVF LPGSRQTLSI
YQALKKGLLS AEVARLLLEA QAATGFLLDP VKGERLTVDE AVRKGLVGPE LHDRLLSAER
AVTGYRDPYT EQTISLFQAM KKDLIPAEEA LRLLDAQLAT GGIVDPRLGF HLPLEVAYQR
GYLNKDTHDQ LSEPSEVRSY VDPSTDERLS YTQLLKRCRR DDSTGQLLLP LSDAHKLTFR
GLRKQITVEE LVRSQVMDEA TALQLREGLT SIEEVTKNLQ KFLEGTSCIA GVFVDATKER
LSVYQAMKKG IIRPGTAFEL LEAQAATGYV IDPIKGLKLT VEEAVRMGIV GPEFKDKLLS
AERAVTGYKD PYSGKLISLF QAMKKGLILK DHGIRLLEAQ IATGGIIDPE ESHRLPVEVA
YKRGLFDEEM NEILTDPSDD TKGFFDPNTE ENLTYLQLME RCITDPQTGL CLLPLKEKKR
ERKTSSKSSV RKRRVVIVDP ETGKEMSVYE AYRKGLIDHQ TYLELSEQEC EWEEITISSS
DGVVKSMIID RRSGRQYDID DAITKNLIDR SALDQYRAGT LSITEFADML SGNASGFRSR
SSSVGSSSSY PISPAVSRPQ LASWSDPTEE TGPVAGILDT ETLEKVSITE AMHRSLVDNI
TGQRLLEAQA CTGGIIDPST GERFPVTDAV NKGLVDKIMV DRINLAQKAF CGFEDPRTKT
KMSAAQALRK GWLYYEAGQR FLEVQYLTGG LIEPDTPGRV SLDEALQRGT VDARTAQKLR
DVGAYSKYLT CPKTKLKISY KDALDRSMVE EGTGLRLLEA AAQSSKGYYS PYSVSGSGST
AGSRAGSRTG SRAGSRRGSF DATGSGFSMT FSSSSYSSSG YGRRYASGSS ASLGGPESAV
A
//
