ID F7HTY4_MACMU Unreviewed; 560 AA.
AC F7HTY4; H9ZF07;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=DDB1 and CUL4 associated factor 15 {ECO:0000313|Ensembl:ENSMMUP00000010918.4};
GN Name=DCAF15 {ECO:0000313|Ensembl:ENSMMUP00000010918.4,
GN ECO:0000313|VGNC:VGNC:71706};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|Ensembl:ENSMMUP00000010918.4, ECO:0000313|Proteomes:UP000006718};
RN [1] {ECO:0000313|Proteomes:UP000006718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=17573 {ECO:0000313|Proteomes:UP000006718};
RX PubMed=17431167; DOI=10.1126/science.1139247;
RA Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M.,
RA Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., Wilson R.K.,
RA Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., Hardison R.C.,
RA Makova K.D., Miller W., Milosavljevic A., Palermo R.E., Siepel A.,
RA Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J.,
RA Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., Dinh H.H.,
RA Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., Godfrey J.,
RA Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N.,
RA Joshi V., Khan Z.M., Kirkness E.F., Cree A., Fowler R.G., Lee S.,
RA Lewis L.R., Li Z., Liu Y.-S., Moore S.M., Muzny D., Nazareth L.V.,
RA Ngo D.N., Okwuonu G.O., Pai G., Parker D., Paul H.A., Pfannkoch C.,
RA Pohl C.S., Rogers Y.-H.C., Ruiz S.J., Sabo A., Santibanez J.,
RA Schneider B.W., Smith S.M., Sodergren E., Svatek A.F., Utterback T.R.,
RA Vattathil S., Warren W., White C.S., Chinwalla A.T., Feng Y., Halpern A.L.,
RA Hillier L.W., Huang X., Minx P., Nelson J.O., Pepin K.H., Qin X.,
RA Sutton G.G., Venter E., Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P.,
RA Jones S.M., Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L.,
RA Csuros M., Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H.,
RA Liu Y., Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E.,
RA Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J.,
RA Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J.,
RA Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A.,
RA Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., Denby A.,
RA Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., Marklein A.,
RA Nielsen R., Vallender E.J., Clark A.G., Ferguson B., Hernandez R.D.,
RA Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., Pu L.-L., Ren Y.,
RA Smith D.G., Wheeler D.A., Schenck I., Ball E.V., Chen R., Cooper D.N.,
RA Giardine B., Hsu F., Kent W.J., Lesk A., Nelson D.L., O'brien W.E.,
RA Pruefer K., Stenson P.D., Wallace J.C., Ke H., Liu X.-M., Wang P.,
RA Xiang A.P., Yang F., Barber G.P., Haussler D., Karolchik D., Kern A.D.,
RA Kuhn R.M., Smith K.E., Zwieg A.S.;
RT "Evolutionary and biomedical insights from the rhesus macaque genome.";
RL Science 316:222-234(2007).
RN [2] {ECO:0000313|Ensembl:ENSMMUP00000010918.4}
RP IDENTIFICATION.
RC STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000010918.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F7HTY4; -.
DR SMR; F7HTY4; -.
DR Ensembl; ENSMMUT00000011645.4; ENSMMUP00000010918.4; ENSMMUG00000008326.4.
DR VEuPathDB; HostDB:ENSMMUG00000008326; -.
DR VGNC; VGNC:71706; DCAF15.
DR eggNOG; ENOG502QQCQ; Eukaryota.
DR GeneTree; ENSGT00390000011987; -.
DR HOGENOM; CLU_031970_0_0_1; -.
DR TreeFam; TF329680; -.
DR Proteomes; UP000006718; Chromosome 19.
DR Bgee; ENSMMUG00000008326; Expressed in testis and 20 other cell types or tissues.
DR ExpressionAtlas; F7HTY4; baseline and differential.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd20913; DCAF15-CTD; 1.
DR CDD; cd20917; DCAF15-NTD; 1.
DR InterPro; IPR038914; DCAF15.
DR InterPro; IPR047319; DCAF15_C.
DR InterPro; IPR032734; DCAF15_WD40.
DR PANTHER; PTHR28541; DDB1- AND CUL4-ASSOCIATED FACTOR 15; 1.
DR PANTHER; PTHR28541:SF1; DDB1- AND CUL4-ASSOCIATED FACTOR 15; 1.
DR Pfam; PF14939; DCAF15_WD40; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006718}.
FT DOMAIN 49..259
FT /note="DDB1- and CUL4-associated factor 15 WD40 repeat-
FT containing"
FT /evidence="ECO:0000259|Pfam:PF14939"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 278..315
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 278..299
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 560 AA; 61633 MW; AA2908E9E45F1797 CRC64;
MAPSSKSERN SGAGSGGGGP GGAGGKRAAG RRREHVLKQL ERVKISGQLS PRLFRKLPPR
VCVSLKNIVD EDFLYAGHIF LGFSKCGRYV LSYTSSSGDD DFSFYIYHLY WWEFNVHSKL
KLVRQVRLFQ DEEIYSDLYL TVCEWPSDAS KVIVFGFNTR SANGMLMNMM MMSDENHRDI
YVSTVAVPPP GRCAACQDAS RAHPGDPNAQ CLRHGFMLHT KYQVVYPFPT FQPAFQLKKD
QVVLLNTSYS LVACAVSVHS AGDRSFCQIL YDHSTCPPAP ASPPEPQSPE LPPALPSFCP
EAAPARSSGS PEPSPAIAKA KEFVADIFRR AKEAKGGAPE EARPALCPGP SGSRCRAHSE
PLALCGEAAP RDSPPASEAP APEPGYINYT KLYYVLESGE GTEPEDEFED DKISLPFVVT
DLRGRNLRPM RERTAVQGQY LTVEQLTLDF EYVINEVIRH DATWGHQFCS FSDYDIVILE
VCPETNQVLI NIGLLLLAFP SPTEEGQLRV LPEGSGRQRA IHVDRAVRAG PPRTLTPTTS
AAWDRPPPRG GLFLAGWPTD
//
