ID F7HUR4_CALJA Unreviewed; 913 AA.
AC F7HUR4;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=NF-X1-type zinc finger protein NFXL1 {ECO:0000313|EMBL:JAB25466.1};
DE SubName: Full=Nuclear transcription factor, X-box binding like 1 {ECO:0000313|Ensembl:ENSCJAP00000035160.1};
GN Name=NFXL1 {ECO:0000313|EMBL:JAB25466.1,
GN ECO:0000313|Ensembl:ENSCJAP00000035160.1};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|EMBL:JAB25466.1};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000035160.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:JAB25466.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Bladder {ECO:0000313|EMBL:JAB07347.1}, Cerebellum
RC {ECO:0000313|EMBL:JAB42575.1}, Cerebral cortex
RC {ECO:0000313|EMBL:JAB25466.1}, and Hippocampus
RC {ECO:0000313|EMBL:JAB13472.1};
RX PubMed=25243066; DOI=10.1186/2047-217X-3-14;
RA Maudhoo M.D., Ren D., Gradnigo J.S., Gibbs R.M., Lubker A.C.,
RA Moriyama E.N., French J.A., Norgren R.B.Jr.;
RT "De novo assembly of the common marmoset transcriptome from NextGen mRNA
RT sequences.";
RL Gigascience 3:14-14(2014).
RN [3] {ECO:0000313|Ensembl:ENSCJAP00000035160.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the NFX1 family.
CC {ECO:0000256|ARBA:ARBA00007269}.
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DR EMBL; GAMT01004514; JAB07347.1; -; mRNA.
DR EMBL; GAMS01009664; JAB13472.1; -; mRNA.
DR EMBL; GAMR01008466; JAB25466.1; -; mRNA.
DR EMBL; GAMP01010180; JAB42575.1; -; mRNA.
DR RefSeq; XP_008991633.1; XM_008993385.2.
DR STRING; 9483.ENSCJAP00000035160; -.
DR Ensembl; ENSCJAT00000037125.4; ENSCJAP00000035160.1; ENSCJAG00000018893.5.
DR eggNOG; KOG1952; Eukaryota.
DR GeneTree; ENSGT00940000157059; -.
DR HOGENOM; CLU_014224_0_0_1; -.
DR OMA; KCQSVCH; -.
DR OrthoDB; 1412at2759; -.
DR TreeFam; TF323611; -.
DR Proteomes; UP000008225; Chromosome 3.
DR Bgee; ENSCJAG00000018893; Expressed in ovary and 6 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd06008; NF-X1-zinc-finger; 6.
DR CDD; cd16697; RING-CH-C4HC3_NFXL1; 1.
DR InterPro; IPR034078; NFX1_fam.
DR InterPro; IPR000967; Znf_NFX1.
DR InterPro; IPR001841; Znf_RING.
DR PANTHER; PTHR12360:SF1; NF-X1-TYPE ZINC FINGER PROTEIN NFXL1; 1.
DR PANTHER; PTHR12360; NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1; 1.
DR Pfam; PF01422; zf-NF-X1; 11.
DR SMART; SM00438; ZnF_NFX; 12.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT TRANSMEM 891..909
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 162..222
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 1..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 102..121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 832..872
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 58..74
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 913 AA; 101797 MW; DD6A0D65B08E5E4C CRC64;
MEASWRQVAG GRGRARGRAS AAPSSGNGVH LRGAGGGREK GSGGEVPSGA IPGGVATTAA
ARSSNSPAGS QALQTPAVHE LMSQKKFEEI KKANQAAARK LVEEHFSSSS EEEGDEDFEG
KQGRIVANTF ITYTTQTDGD IRELERTKQY VNEAFQAGAM TCLICIASVK RNQAVWSCLG
CFCIFHMPCI QKWAKDSQFL VSSVTDDDFG KRDYPWPCPK CRFEYKRSET PSRYYCYCGK
VEDPPLDPWL VPHSCGQVCE REFKPPCGHK CLLLCHPGPC PPCPKMVTTT CYCKKAKPIP
RRCSAKEWSC QLPCGRKLLC GQHKCENPCH AGSCQPCPRV SRQKCVCGKK VAERSCSSPL
WHCDQVCGKT LPCGNHTCEQ VCHVDTCGEC PRSGKRFCPC QKSKFSLPCT EDVPTCGDSC
DKVLECGIHR CSQRCHRGPC ETCRQEVEKH CRCGKHTKRM PCHKPYLCET KCVKMRDCQK
HQCRRKCCPG NCPPCDQNCG RTLGCRNHKC PSVCHRGSCY PCPETVDVKC NCGNTKVTVP
CGRERTTRPP KCKEQCSRPP TCHHISQEKH RCHFGSCPPC HQPCQKVLEK CGHLCPAPCH
DQALIKQTGK HQPTGPWEQP SEPAFIQTAL PCPPCQVPIP VECLGKHEVS PLPCHAVGPY
SCKRVCGRIL DCQNHTCMKE CHKVTEIDGS TGKNKAGPEC LHCDEGCSRS RPLGCLHPCV
LPCHPGECPP CVQMLRIKCH CKITSLYVEC RKITTADVNE KNLLSCCKNQ CPKELPCGHR
CKEMCHPGEC PFNCNQKVKL RCPCKRIKKE LQCNKVRENQ VSIECDTTCK EMKRKASEIK
EAEAKAAYEE EKRRQQAELE AFENRLKGRR KKNRKRDEVA VELSPWQKHK YYLLSVCGAV
VVVFAWYITH DVD
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