ID F7I493_CALJA Unreviewed; 1198 AA.
AC F7I493;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 3.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Sorbin and SH3 domain containing 2 {ECO:0000313|Ensembl:ENSCJAP00000011119.4};
GN Name=SORBS2 {ECO:0000313|Ensembl:ENSCJAP00000011119.4};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000011119.4, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000011119.4}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000011119.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F7I493; -.
DR Ensembl; ENSCJAT00000011736.5; ENSCJAP00000011119.4; ENSCJAG00000006015.5.
DR GeneTree; ENSGT00940000157056; -.
DR Proteomes; UP000008225; Chromosome 3.
DR Bgee; ENSCJAG00000006015; Expressed in heart and 6 other cell types or tissues.
DR CDD; cd11920; SH3_Sorbs2_1; 1.
DR CDD; cd11923; SH3_Sorbs2_2; 1.
DR CDD; cd11917; SH3_Sorbs2_3; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR003127; SoHo_dom.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR14167:SF56; DREBRIN-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR Pfam; PF00018; SH3_1; 2.
DR Pfam; PF14604; SH3_9; 1.
DR Pfam; PF02208; Sorb; 1.
DR PRINTS; PR00499; P67PHOX.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 3.
DR SMART; SM00459; Sorb; 1.
DR SUPFAM; SSF50044; SH3-domain; 3.
DR PROSITE; PS50002; SH3; 3.
DR PROSITE; PS50831; SOHO; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 165..226
FT /note="SoHo"
FT /evidence="ECO:0000259|PROSITE:PS50831"
FT DOMAIN 961..1020
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 1036..1097
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 1139..1198
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 25..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 70..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 234..408
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 892..911
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 916..963
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1100..1126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 76..95
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 234..262
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 266..281
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 282..312
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 325..349
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 377..402
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 934..948
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 949..963
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1198 AA; 133792 MW; 96B9FF486AB7B24D CRC64;
MNTDSGGSAR KRAAMSVTLT SVKRVQSSPN LLAAGRDSQS PDSAWRSYHG NQEALNGDAT
YSSLAAKGFR SVRPNLQDKR SPTQSQITVN GNSGGAVSPM SYYQRPFSPS AYSLPASLNS
SIVMQHGTSL DSAETYPQHA QSLDGTSSSS IPLYRSSEEE KRVTVIKAPH YPGIGPVDES
GIPTAIRTTV DRPKDWYKTM FKQIHMVHKP DDDTDMYNTP YAYNAGLYNP PYSAQSHPAA
KTQTYRPLSK SHSDNSTHAF KDASSPVPPP HVPPPVPPLR PRDRSSTEKH DWDPPDRKVD
TRKFRSEPRS IFEYEPGKSS ILQHERPASL YQSSIDRSLE RPMSSASSAS DFRKRRKSEP
AVGPPRGLGD QRTSPGRADL PGSSTTLTKS FTSSSPSSPS RAKGGDDSKM CPSLCSYSGL
DGNPPSELDY CSTYRQLLDV PRDSPRAITF KNGWQMARQN AEIWSSTEET VSPKIKSRSC
DDLLNDDCDS FPDPKIKSES MGSLLCDKDS KGSCAITWGS PYIQEVRSNG RSRIRHRSAH
NAPGFLKMYK KMHRINRKDL MNSEVICSVK SRILQYENEQ QPKGLGHAWS QSSTEEVPRD
MVPTRISEFE KLIQKSKSMP NLGDDALSPV TLEPPRNGLC PKRRFSIEYL LEDEDEGGRP
APAPRGCASN ALVPIHIEVT SHEQPRAHVE FSDSDQDGVV SDHSDYIHVE GSSFCSESDL
DHFSFTSSES FYGSSHHHHH HHHHHHHHRH LISSCKGRCP ASYTRFTTML KHERARHENT
EEPRRPEMDP GLSKLAFLVS PVPFRRKRNS APKKQTEKAK CKASVFEALD SALKDICDQI
KAEKKRGSLP DNSILHRLIS ELLPDVPERN SSLSVLRRSP LHLPLHPLPP DGAIHCPPYQ
NDGGRTPLSA SFQDVDTASN SYHPQDRGGT LQDRESPRSY SSTLTDMGRS GPRERRGTPE
KEKLPAKAVY DFKAQTSKEL SFKKGDTVYI LRKIDQNWYE GEHHGRVGIF PISYVEKLTP
PEKAQPARPP PPAQPGEIGE AIAKYNFSAD TNVELSLRKG DRVILLKRVD QNWYEGKIPG
ANRQGIFPVS YVEVVKKNTK GAEDYPDPPM PHSYSSDRIH SLSSNKPQRP VFTHENIQGG
GEPFQALYNY TPRNEDELEL RESDVIDVME KCDDGWFVGT SRRTKFFGTF PGNYVKRL
//
