ID F7I5J8_CALJA Unreviewed; 485 AA.
AC F7I5J8;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 4.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=Tektin {ECO:0000256|RuleBase:RU367040};
GN Name=TEKT5 {ECO:0000313|Ensembl:ENSCJAP00000031495.5};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000031495.5, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000031495.5}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000031495.5}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Microtubule inner protein (MIP) part of the dynein-decorated
CC doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms
CC filamentous polymers in the walls of ciliary and flagellar
CC microtubules. Required for normal sperm mobility.
CC {ECO:0000256|RuleBase:RU367040}.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium, flagellum
CC {ECO:0000256|RuleBase:RU367040}.
CC -!- SIMILARITY: Belongs to the tektin family.
CC {ECO:0000256|ARBA:ARBA00007209, ECO:0000256|RuleBase:RU367040}.
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DR RefSeq; XP_002755932.2; XM_002755886.3.
DR AlphaFoldDB; F7I5J8; -.
DR STRING; 9483.ENSCJAP00000031495; -.
DR Ensembl; ENSCJAT00000033295.5; ENSCJAP00000031495.5; ENSCJAG00000017139.5.
DR eggNOG; KOG2685; Eukaryota.
DR GeneTree; ENSGT00950000182894; -.
DR HOGENOM; CLU_033588_2_1_1; -.
DR InParanoid; F7I5J8; -.
DR OMA; IANVQTC; -.
DR TreeFam; TF320754; -.
DR Proteomes; UP000008225; Chromosome 12.
DR Bgee; ENSCJAG00000017139; Expressed in liver and 2 other cell types or tissues.
DR GO; GO:0015630; C:microtubule cytoskeleton; IEA:UniProtKB-UniRule.
DR GO; GO:0031514; C:motile cilium; IEA:UniProtKB-SubCell.
DR GO; GO:0060271; P:cilium assembly; IEA:UniProtKB-UniRule.
DR GO; GO:0030317; P:flagellated sperm motility; IEA:UniProtKB-UniRule.
DR InterPro; IPR048256; Tektin-like.
DR InterPro; IPR000435; Tektins.
DR PANTHER; PTHR19960; TEKTIN; 1.
DR PANTHER; PTHR19960:SF23; TEKTIN-5; 1.
DR Pfam; PF03148; Tektin; 1.
DR PRINTS; PR00511; TEKTIN.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|RuleBase:RU367040};
KW Cilium {ECO:0000256|RuleBase:RU367040};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Flagellum {ECO:0000256|RuleBase:RU367040};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225}.
FT COILED 152..179
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 485 AA; 56461 MW; 194FE3F4952D891B CRC64;
MEFLGTTQTA SYCGPKKRCG LTSLPAVQAP VIQECYQPYY LPGYRYLNSW RPSLFYKISN
VQTCPDETSS TLRPPTILPA LRSSLFSRYS PHDWDQSNQL QVRGAEASRL WASRLTDDSM
RLLQDKDQLT HQMQEGTSRN LGQRLSDIGF WKSELSYELD RLLTENQNLE MVKRRLECAA
DEVNSPLQVA LECLYHREKR IGIDLVHDNV EKNLIREVDL LKCCQEQMRK LAQRIDMQMR
DNRDAQHALE RDLEDKSSAQ FIDEKCFNLR NTSDCISFFH GMEKIDGTIS VPETWAKFSN
DNIKHSQNMR ANSIRLREEA EHLFETLSDQ MWRQFTDTNL AFNARISEVT DVKNKLQVQL
AKTLQEIFQA ENTIMLLERS IMAKEGPLKV AQTRLECRTW RPNMELCRDT PQFKLVNEVF
TIDDTLQTLK LRLRETQDTL QLLVMTKCRL EHELAIKANT LCIDKEKCMG MRKTFPCTPR
LVGHT
//
