ID F7IBK6_CALJA Unreviewed; 1113 AA.
AC F7IBK6;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 3.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=TATA-box binding protein associated factor 4 {ECO:0000313|Ensembl:ENSCJAP00000026568.4};
GN Name=TAF4 {ECO:0000313|Ensembl:ENSCJAP00000026568.4};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000026568.4, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000026568.4}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000026568.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TAF4 family.
CC {ECO:0000256|ARBA:ARBA00006178}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; F7IBK6; -.
DR Ensembl; ENSCJAT00000028082.5; ENSCJAP00000026568.4; ENSCJAG00000014438.5.
DR GeneTree; ENSGT00390000011620; -.
DR HOGENOM; CLU_010576_2_1_1; -.
DR OMA; LAMARCP; -.
DR OrthoDB; 2910924at2759; -.
DR Proteomes; UP000008225; Chromosome 5.
DR Bgee; ENSCJAG00000014438; Expressed in testis and 6 other cell types or tissues.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0001673; C:male germ cell nucleus; IEA:Ensembl.
DR GO; GO:0071339; C:MLL1 complex; IEA:Ensembl.
DR GO; GO:0005669; C:transcription factor TFIID complex; IEA:Ensembl.
DR GO; GO:0033276; C:transcription factor TFTC complex; IEA:Ensembl.
DR GO; GO:0017162; F:aryl hydrocarbon receptor binding; IEA:Ensembl.
DR GO; GO:0001046; F:core promoter sequence-specific DNA binding; IEA:Ensembl.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0016251; F:RNA polymerase II general transcription initiation factor activity; IEA:Ensembl.
DR GO; GO:0042789; P:mRNA transcription by RNA polymerase II; IEA:Ensembl.
DR GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR GO; GO:0060261; P:positive regulation of transcription initiation by RNA polymerase II; IEA:Ensembl.
DR GO; GO:0051123; P:RNA polymerase II preinitiation complex assembly; IEA:Ensembl.
DR CDD; cd08045; TAF4; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR Gene3D; 1.20.120.1110; TAFH/NHR1 domain; 1.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR045144; TAF4.
DR InterPro; IPR007900; TAF4_C.
DR InterPro; IPR037249; TAFH/NHR1_dom_sf.
DR InterPro; IPR003894; TAFH_NHR1.
DR PANTHER; PTHR15138; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4; 1.
DR PANTHER; PTHR15138:SF18; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4; 1.
DR Pfam; PF05236; TAF4; 1.
DR Pfam; PF07531; TAFH; 1.
DR SMART; SM00549; TAFH; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
DR SUPFAM; SSF158553; TAFH domain-like; 1.
DR PROSITE; PS51119; TAFH; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 619..716
FT /note="TAFH"
FT /evidence="ECO:0000259|PROSITE:PS51119"
FT REGION 66..137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 149..203
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 241..454
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 509..528
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 596..615
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1043..1078
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 82..128
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 174..188
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 289..308
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 390..428
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1062..1078
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1113 AA; 116309 MW; DD670ECEEC379383 CRC64;
MAAGSDLLDE VFFNSEVDEK VVSDLVGSLE SQLAASAAHH HHLAQRTPEV RAAAAGALGN
HVVSGSPAGA AGAGPAAPAE GAPGAAPEPP PAGRARPGGG GPRRPGPPSP RLPLVPAGPA
PPAAKLRPPP EGSAGACAPV PAAAAAAAAG PEPAPAGPAK PAGPAALAAR AGPGPGPGPG
PGPGPGKPAG PGAAQTLNGS AALLNSHHAA APAVSLVNNG PAALLPLPKP AAPGTVIQTS
PFVGAGAPPR ARRALAPCRP RARRPRSCPA PAVPRAHHPG PAARPPHRTP DRRARRAAPR
RRPERGQRRS GPRPRPDHWG PRGGQRTAWA RRGGRGARAG GQGRVAQDGG AGGPPASADP
GGQRPGQHGG QHGHRANYAR GFAQSRRRPA ACPRDPHRAA QRRGRRGDPE PAPDAYGHHQ
RDPGHSDAHR AGSSSAAAAS EPDQHPELPA APRRWRNTCL EKGISAVFVM SDPGTHLHLL
FKGMVLVRSE NGQLLMIPQQ ALAQMQAQAH AQPQTTMAPR PATPTSAPPV QISTVQAPGT
PIIARQVTPT TIIKQVSQAQ TTVQPSATLQ RSPGVQPQLV LGGAAQTASL GTATAVQTGT
PQRTVPGATT TSSAATETME NVKKCKNFLS TLIKLASSGK QSTETAANVK ELVQNLLDGK
IEAEDFTSRL YRELNSSPQP YLVPFLKRSL PALRQLTPDS AAFIQQSQQQ PPPASQATTA
LTAVVLSGSV QRTAGKTAAT VTSALQPPVL SLTQPTQVGV GKQGQPTPLV IQQPPKPGAL
IRPPQVTLTQ TPMVALRQPH NRIMLTTPQP VQLSPLQPVP VVKPAVLPGA KALSAVSAQA
AAAQKNKLKE PGGGSFRDDD DINDVASMAG VNLSEESARI LATNSELVGT LTRSCKDETF
LLSAPLQRRI LEIGKKHGIT ELHPDVVSYV SHATQQRLQN LVEKISETAQ QKNFSYKDDD
RYEQASDVRA QLKFFEQLDQ IEKQRKDEQE REILMRAAKS RSRQEDPEQL RLKQKAKEMQ
QQELAQMRQR DANLTALAAI GPRKKRKVDC PGPGSGAEGS GSGSVVPGSS GVGTPRQFTR
QRITRVNLRD LIFCLENERE TSHSLLLYKA FLK
//
