ID   F7ID27_CALJA            Unreviewed;       898 AA.
AC   F7ID27;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   25-MAY-2022, sequence version 3.
DT   27-MAR-2024, entry version 40.
DE   SubName: Full=Thyroglobulin {ECO:0000313|Ensembl:ENSCJAP00000008444.4};
GN   Name=TG {ECO:0000313|Ensembl:ENSCJAP00000008444.4};
OS   Callithrix jacchus (White-tufted-ear marmoset).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Callitrichinae; Callithrix; Callithrix.
OX   NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000008444.4, ECO:0000313|Proteomes:UP000008225};
RN   [1] {ECO:0000313|Ensembl:ENSCJAP00000008444.4}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCJAP00000008444.4}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC       {ECO:0000256|ARBA:ARBA00005964}.
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DR   AlphaFoldDB; F7ID27; -.
DR   ESTHER; calja-f7id21; Thyroglobulin.
DR   Ensembl; ENSCJAT00000008929.5; ENSCJAP00000008444.4; ENSCJAG00000004602.5.
DR   GeneTree; ENSGT00940000159300; -.
DR   HOGENOM; CLU_003031_0_0_1; -.
DR   Proteomes; UP000008225; Chromosome 16.
DR   Bgee; ENSCJAG00000004602; Expressed in ovary and 2 other cell types or tissues.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002018; CarbesteraseB.
DR   InterPro; IPR019819; Carboxylesterase_B_CS.
DR   PANTHER; PTHR14093; HLA CLASS II GAMMA CHAIN; 1.
DR   PANTHER; PTHR14093:SF19; THYROGLOBULIN; 1.
DR   Pfam; PF00135; COesterase; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   PROSITE; PS00941; CARBOXYLESTERASE_B_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008225}.
FT   DOMAIN          333..852
FT                   /note="Carboxylesterase type B"
FT                   /evidence="ECO:0000259|Pfam:PF00135"
FT   REGION          863..898
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   898 AA;  99056 MW;  8542FAC33A0E46E7 CRC64;
     TLPGLTTELF SAVDLDQVIV NENRSLPIQK HWLFKHLFSA QEANLWCLSR CVQEHSFCQL
     AEIITDNGSM YFTCTLYPEA QVCDDIMESS PQGCRLILPQ RPMALFRKKV ILEDKVKNFY
     TRLPFQKLMG LSIRNKVPMS EKSISNGFFE CERLCDMDPC CTGFGFLNVS QLKGGEVTCL
     TLNSLGLQMC SEENGGAWRI LDCGSPDIEV HTYPFGWYQK PISLDSWQSL ALSSVVVDPS
     IRNFDVAHVS TAAASNFSAV RDLCLSECSQ HEACLTTTLQ TQPGAMRCMF YPDTQSCTHS
     LQGQYCHLLL REEATHIYRK QGISLLSYEA SVPSVPIATH GKLLGRSQAI QVGTSWKQVD
     QFLGVPYAAP PLAERRFRAP EPLNWTGSWD ASKLRASCWQ PGTRTSMSPG VSEDCLYLNV
     FIPQNVAPNT SVLVFFHNTM EGKGSEGWPA IDGSFLAAVG NLIVVTASYR VGVFGFLSSG
     SGEVSGNWGL LDQVAALTWV QTHIRAFGGD PRRVSLAADR GGADVASIHL LTARATNSRL
     FRRAVLMGGS ALSPAAIISH ERAQQQAVAL AKEVSCPMSS SQEVVSCLRQ KPASVLNDAQ
     TKLLAVSGPF HYWSPVVDGQ FLREAPARAL KRTLQVEVDL LIGSSQDDGL INRAKAVKQF
     EESQGRTSSK TAFYQALQNS LGGEDSDARV EAAATWYYSL EHSSDDYASF SRALENATRD
     YFITCPIIDM ASAWAKRTRG NVFMYHAPKS YGHGSLELLV DVQFAFGLPF YPAYEGQFSL
     EEKSLSLKIM QYFSHFIRSG NPNYPYEFSR KVPDFASPWP DFVPSAGGEN YKEFSTQLPN
     RQGLKKADCS FWSKYISSLK ASADGAKGGQ LAESEEEELT AGSGVKEDLL SLQEPYSK
//