ID F7IFJ7_CALJA Unreviewed; 1019 AA.
AC F7IFJ7; U3CZ44;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 3.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Thrombospondin type 1 domain containing 4 {ECO:0000313|Ensembl:ENSCJAP00000034505.4};
DE SubName: Full=Thrombospondin type-1 domain-containing protein 4 {ECO:0000313|EMBL:JAB06721.1};
GN Name=THSD4 {ECO:0000313|EMBL:JAB06721.1,
GN ECO:0000313|Ensembl:ENSCJAP00000034505.4};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000034505.4, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000034505.4}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:JAB06721.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Bladder {ECO:0000313|EMBL:JAB06721.1};
RX PubMed=25243066; DOI=10.1186/2047-217X-3-14;
RA Maudhoo M.D., Ren D., Gradnigo J.S., Gibbs R.M., Lubker A.C.,
RA Moriyama E.N., French J.A., Norgren R.B.Jr.;
RT "De novo assembly of the common marmoset transcriptome from NextGen mRNA
RT sequences.";
RL Gigascience 3:14-14(2014).
RN [3] {ECO:0000313|Ensembl:ENSCJAP00000034505.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; GAMT01005140; JAB06721.1; -; mRNA.
DR RefSeq; XP_009003412.1; XM_009005164.2.
DR STRING; 9483.ENSCJAP00000034505; -.
DR Ensembl; ENSCJAT00000036441.4; ENSCJAP00000034505.4; ENSCJAG00000018572.4.
DR GeneTree; ENSGT00940000156594; -.
DR HOGENOM; CLU_051506_0_0_1; -.
DR OMA; RRCMHSV; -.
DR OrthoDB; 2910701at2759; -.
DR Proteomes; UP000008225; Chromosome 10.
DR Bgee; ENSCJAG00000018572; Expressed in heart and 6 other cell types or tissues.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0001527; C:microfibril; IEA:Ensembl.
DR GO; GO:0048251; P:elastic fiber assembly; IEA:Ensembl.
DR GO; GO:0160054; P:microfibril assembly; IEA:Ensembl.
DR Gene3D; 2.60.120.830; -; 1.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 7.
DR InterPro; IPR045371; ADAMTS_CR_3.
DR InterPro; IPR010294; ADAMTS_spacer1.
DR InterPro; IPR010909; PLAC.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR PANTHER; PTHR13723; ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE; 1.
DR PANTHER; PTHR13723:SF16; THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN 4; 1.
DR Pfam; PF19236; ADAMTS_CR_3; 1.
DR Pfam; PF05986; ADAMTS_spacer1; 1.
DR Pfam; PF08686; PLAC; 1.
DR Pfam; PF19030; TSP1_ADAMTS; 6.
DR Pfam; PF00090; TSP_1; 1.
DR SMART; SM00209; TSP1; 7.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 7.
DR PROSITE; PS50900; PLAC; 1.
DR PROSITE; PS50092; TSP1; 6.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..1019
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041197494"
FT DOMAIN 972..1009
FT /note="PLAC"
FT /evidence="ECO:0000259|PROSITE:PS50900"
FT REGION 31..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 117..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 187..236
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 261..280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 535..624
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 143..161
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 199..214
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 548..579
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1019 AA; 112948 MW; 78485CEF1594A3AB CRC64;
MVSHFMGSFS VLGSLLLLGF QFVCPQPSTQ HRKVPQRMAT EGAPEDGGGG SGAPGVWGSW
GPWSACSRSC SGGVMQQTRP CLPRSYRVRS GPRPSTPART FVDHVVSAVR TSVPLHRYRD
EQQALASSDA SRQGPAMLRG SRHPQPHSRE VTTDRRSRTR GPIGPGKYGY GKAPYILPLQ
TDTTHMPQRL RRQKPSSRHS RSQGASSARL SHSSPAHPVP QHGPLYQSDS GPRSGLQAAE
APIYQLPLTH DQGFQAASSL FHSPETSNNH GVGTHGAAQS FSQPARSTAI SCIGAYRQYK
LCNTNVCPES SRSIREVQCA SYNNKPFMGR FYEWEPFAEV KGNRKCELNC QAMGYRFYVR
QAEKVIDGTP CDQNGTAICV SGQCKNIGCD DYLGSDKVVD KCGVCGGDNT GCQVVSGVFK
HALTSLGYHR VVEIPQGATK INITEMYKSN NYLALRSRSG RSIINGNWAI DRPGKYEGGG
TMFTYKRPNE ISSTAGESFL AEGPTNEILD VYMIHQQPNP GVHYEYVIMG TNAISPQVPP
HRRPGEPFNG QLETERRSQE EGEAKGRNEK KEDLRGEAPE TFTSESAQTF PVRHPDRFSP
RRPDTLVPPA PQPPRRSRDH NWKQLGTTEC STTCGKGSQY PIFRCVHRST HEEAPESYCD
SSMKPSPEEE PCNIFPCPAF WDIGEWSECS KTCGLGMQHR QVLCRQVYAN RSLTVQPYRC
QHLEKPETTS TCQLKICSEW QIRTDWTSCS VPCGVGQRTR DVKCVSNIGD VVDDEECNMK
LRPNDIENCD MGPCAKSWFL TEWSERCSAE CGAGVRTRSV VCMTNHVSSL PLEGCGNNRP
AEATPCDNGP CTGKVEWFTG SWSQCSIECG SGTQQREVIC VRKNADTFEV LDPSECSFLE
KPPSQQSCHL KPCGAKWFST EWSMCSKSCQ GGFRVREVRC LSDDMALSNL CDPQLKPEER
ESCNPQDCVP EVDENCKDKY YNCNVVVQAR LCVYNYYKTA CCASCTRVAN RQTGFLRSR
//
