ID F7IHU2_CALJA Unreviewed; 407 AA.
AC F7IHU2;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Centrosomal protein 57kDa-like protein 1 {ECO:0000256|ARBA:ARBA00041218};
DE AltName: Full=Cep57-related protein {ECO:0000256|ARBA:ARBA00042578};
GN Name=CEP57L1 {ECO:0000313|Ensembl:ENSCJAP00000010728.3};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000010728.3, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000010728.3}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000010728.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome {ECO:0000256|ARBA:ARBA00004300}.
CC -!- SIMILARITY: Belongs to the translokin family.
CC {ECO:0000256|ARBA:ARBA00008179}.
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DR AlphaFoldDB; F7IHU2; -.
DR Ensembl; ENSCJAT00000011331.4; ENSCJAP00000010728.3; ENSCJAG00000005825.5.
DR GeneTree; ENSGT00530000063695; -.
DR HOGENOM; CLU_034321_1_0_1; -.
DR Proteomes; UP000008225; Chromosome 4.
DR Bgee; ENSCJAG00000005825; Expressed in testis and 6 other cell types or tissues.
DR GO; GO:0005813; C:centrosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0043015; F:gamma-tubulin binding; IEA:InterPro.
DR GO; GO:0042802; F:identical protein binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR Gene3D; 1.20.58.90; -; 1.
DR InterPro; IPR025913; Cep57_CLD.
DR InterPro; IPR024957; Cep57_MT-bd_dom.
DR PANTHER; PTHR19336:SF10; CENTROSOMAL PROTEIN CEP57L1; 1.
DR PANTHER; PTHR19336; UNCHARACTERIZED DUF1167; 1.
DR Pfam; PF14073; Cep57_CLD; 1.
DR Pfam; PF06657; Cep57_MT_bd; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225}.
FT DOMAIN 54..219
FT /note="Cep57 centrosome localisation"
FT /evidence="ECO:0000259|Pfam:PF14073"
FT DOMAIN 260..331
FT /note="Cep57 centrosome microtubule-binding"
FT /evidence="ECO:0000259|Pfam:PF06657"
FT REGION 331..371
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 52..114
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 189..216
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 267..301
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 338..371
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 407 AA; 47167 MW; 3BAF87FFDA9C87CE CRC64;
MDSELMHSIV GSYRKPPERV FVPSFTKNES SQNCHPANLE VTSSKIIHSP NSQALILALK
TLQEKIHRLE LERTQAEDNL NTLSKEAAQY KKALENETNE RNLAHQELIK QKKDISVQLS
SAQSRCTLLE KQLEYTKRMV LNVEREKNMI LEQQAQLQRE KEQDEMKLYA KLEKLDVLEK
ECFRLTATQK TAEDKIKYLE ERLKEEEHQR KLFQDKASEK TKCVKRGSPR QVCSKFGALP
FVAEKPSRTT SWCKAIPTDS EKSISICDNL SELLMAMQDE LDQMSVEHQE LLKQMKETES
HSVFNDIECE LECLVKKMEI KGTQISKLKK HQDSVRKLQQ KVQNSKMSKA SGIQQEGSNP
KGSRNIKNSP RKCLTDTNLF QKNSSFHPIP VHNLQVKLRR DDIMWEQ
//
