ID F7IHW2_CALJA Unreviewed; 497 AA.
AC F7IHW2; F7IHU5;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 2.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Ganglioside induced differentiation associated protein 2 {ECO:0000313|Ensembl:ENSCJAP00000010713.3};
DE SubName: Full=Ganglioside-induced differentiation-associated protein 2 isoform a {ECO:0000313|EMBL:JAB06519.1};
GN Name=GDAP2 {ECO:0000313|EMBL:JAB06519.1,
GN ECO:0000313|Ensembl:ENSCJAP00000010713.3};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000010713.3, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000010713.3}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:JAB06519.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Bladder {ECO:0000313|EMBL:JAB06519.1}, Cerebellum
RC {ECO:0000313|EMBL:JAB50672.1}, Cerebral cortex
RC {ECO:0000313|EMBL:JAB27264.1}, Hippocampus
RC {ECO:0000313|EMBL:JAB13530.1}, and Skeletal muscle
RC {ECO:0000313|EMBL:JAB36531.1};
RX PubMed=25243066; DOI=10.1186/2047-217X-3-14;
RA Maudhoo M.D., Ren D., Gradnigo J.S., Gibbs R.M., Lubker A.C.,
RA Moriyama E.N., French J.A., Norgren R.B.Jr.;
RT "De novo assembly of the common marmoset transcriptome from NextGen mRNA
RT sequences.";
RL Gigascience 3:14-14(2014).
RN [3] {ECO:0000313|Ensembl:ENSCJAP00000010713.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the GDAP2 family.
CC {ECO:0000256|ARBA:ARBA00008355}.
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DR EMBL; GAMT01005342; JAB06519.1; -; mRNA.
DR EMBL; GAMS01009606; JAB13530.1; -; mRNA.
DR EMBL; GAMR01006668; JAB27264.1; -; mRNA.
DR EMBL; GAMQ01005320; JAB36531.1; -; mRNA.
DR EMBL; GAMP01002083; JAB50672.1; -; mRNA.
DR RefSeq; XP_009000229.1; XM_009001981.2.
DR RefSeq; XP_009000230.1; XM_009001982.1.
DR RefSeq; XP_009000231.1; XM_009001983.2.
DR RefSeq; XP_009000233.1; XM_009001985.2.
DR STRING; 9483.ENSCJAP00000010713; -.
DR Ensembl; ENSCJAT00000011313.5; ENSCJAP00000010713.3; ENSCJAG00000005808.5.
DR GeneTree; ENSGT00940000156336; -.
DR OMA; VHLFRYV; -.
DR OrthoDB; 1105329at2759; -.
DR TreeFam; TF324164; -.
DR Proteomes; UP000008225; Chromosome 7.
DR Bgee; ENSCJAG00000005808; Expressed in testis and 6 other cell types or tissues.
DR GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
DR CDD; cd02905; Macro_GDAP2-like; 1.
DR CDD; cd00170; SEC14; 1.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR Gene3D; 3.40.220.10; Leucine Aminopeptidase, subunit E, domain 1; 1.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR InterPro; IPR002589; Macro_dom.
DR InterPro; IPR043472; Macro_dom-like.
DR InterPro; IPR035793; Macro_GDAP2.
DR PANTHER; PTHR11106; GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED; 1.
DR PANTHER; PTHR11106:SF72; GANGLIOSIDE-INDUCED DIFFERENTIATION-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF13716; CRAL_TRIO_2; 1.
DR Pfam; PF01661; Macro; 1.
DR SMART; SM00506; A1pp; 1.
DR SMART; SM00516; SEC14; 1.
DR SUPFAM; SSF52087; CRAL/TRIO domain; 1.
DR SUPFAM; SSF52949; Macro domain-like; 1.
DR PROSITE; PS51154; MACRO; 1.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000008225}.
FT DOMAIN 43..223
FT /note="Macro"
FT /evidence="ECO:0000259|PROSITE:PS51154"
FT REGION 248..273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 497 AA; 56248 MW; A199E5F1CCD43302 CRC64;
MDPLGAPSQF VDVDTLPSWG DSCEDEFNSS DTTAEIFQED TVRSPFLYNK DINGKVVLWK
GDVALLNCTA IVNTSNESLT DKNPVSESIF MLAGPDLKED LQKLKGCRTG EAKLTKGFNL
AARFIIHTVG PKYKSRYRTA AESSLYSCYR NVLQLAKEQS MSSVGFCVIN SAKRGYPLED
ATHIALRTVR RFLEIHGETI EKVVFAVSDL EEATYQKLLP LYFPRSLKEE NRSLPYLPAD
IGNAEGEPVV PERQIRISEK PGAPDDNQEE EDEGLGVDLS FIGSHAFARM EGDIDKQRKL
ILQGQLSEAA LQKQHQRNYN RWLCQARSED LSDIASLKAL YQTGVDNCGR TVMVVVGRNI
PVTLIDMDKA LLYFIHVMDH IAVKEYVLVY FHTLTSEYNH LDSDFLKKLY DVVDVKYKRN
LKAVYFVHPT FRSKVSTWFF TTFSVSGLKD KIHHVDSLHQ LFSAISPEQI DFPPFVLEYD
ARENGPHYTS YPPSPDL
//
