ID   F7II20_CALJA            Unreviewed;       564 AA.
AC   F7II20;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   25-MAY-2022, sequence version 4.
DT   27-MAR-2024, entry version 58.
DE   RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE            EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
OS   Callithrix jacchus (White-tufted-ear marmoset).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Callitrichinae; Callithrix; Callithrix.
OX   NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000023494.5, ECO:0000313|Proteomes:UP000008225};
RN   [1] {ECO:0000313|Ensembl:ENSCJAP00000023494.5}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCJAP00000023494.5}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum lumen
CC       {ECO:0000256|ARBA:ARBA00004319}.
CC   -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC       {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
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DR   AlphaFoldDB; F7II20; -.
DR   Ensembl; ENSCJAT00000024854.5; ENSCJAP00000023494.5; ENSCJAG00000038677.3.
DR   eggNOG; KOG1516; Eukaryota.
DR   GeneTree; ENSGT00940000154623; -.
DR   HOGENOM; CLU_006586_13_0_1; -.
DR   TreeFam; TF315470; -.
DR   Proteomes; UP000008225; Chromosome 20.
DR   Bgee; ENSCJAG00000038677; Expressed in liver and 6 other cell types or tissues.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd00312; Esterase_lipase; 1.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002018; CarbesteraseB.
DR   InterPro; IPR019826; Carboxylesterase_B_AS.
DR   InterPro; IPR019819; Carboxylesterase_B_CS.
DR   PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR   PANTHER; PTHR11559:SF179; LIVER CARBOXYLESTERASE 1-RELATED; 1.
DR   Pfam; PF00135; COesterase; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
DR   PROSITE; PS00941; CARBOXYLESTERASE_B_2; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW   Signal {ECO:0000256|RuleBase:RU361235}.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000256|RuleBase:RU361235"
FT   CHAIN           17..564
FT                   /note="Carboxylic ester hydrolase"
FT                   /evidence="ECO:0000256|RuleBase:RU361235"
FT                   /id="PRO_5035338573"
FT   DOMAIN          21..544
FT                   /note="Carboxylesterase type B"
FT                   /evidence="ECO:0000259|Pfam:PF00135"
SQ   SEQUENCE   564 AA;  62024 MW;  7E99DC3B1F10662D CRC64;
     MSYSFLVALL LALIFGHPSS PPVVDTVHGK VLGKFISLRG FAQPVAVFLG IPFAKPPLGP
     LRFSPPQPPE PWSFVKNATS YPPMCSQDAV AGQVLFELFT NHKENIPLKF SEDCLYLNIY
     TPADLAKKSR LPVMVWIHGG GLLLGGASTY DGLALAAHEN VVVVTIQYRL GIWGFFSTGD
     EHSRGNWGHL DQLAALHWVQ DNIASFGGNP GSVTIFGESA GAESVSVLVF SPLAKNLFHR
     AISESGVALT DVLVEKGDIK PLAEKIATTA GCKTTTSAVM VHCLRQKSEE ELLDTTLKMK
     FLSVDLLGDP RESHTLLPTV IDGVVLPKTP EELQAERKFH PVPYMIGINK QEFGWILPML
     MGFPLSEGKL DQKTAMSLLW NSYPSVKIPK ELIPEAMEKY LGGTDDPVKK KDLVLDLVGD
     VMLGVPSVIV ARNHRDAGAP TYMYEFQYRP SFSSDLKPKT VIGDHGDEIF SVFGAPFLKE
     GGSEEEIRLS KMVMKFWANF ARNGNPNGEG LPHWPEYDQK EGYLQIGAKT QAAQKLKDKE
     VAFWTNLFGK KAVEKPPQTE HIEL
//