ID F7ILR9_CALJA Unreviewed; 2184 AA.
AC F7ILR9;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 4.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Calcineurin binding protein 1 {ECO:0000313|Ensembl:ENSCJAP00000017509.5};
GN Name=CABIN1 {ECO:0000313|Ensembl:ENSCJAP00000017509.5};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000017509.5, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000017509.5}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000017509.5}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR STRING; 9483.ENSCJAP00000017509; -.
DR Ensembl; ENSCJAT00000018518.5; ENSCJAP00000017509.5; ENSCJAG00000031332.4.
DR eggNOG; ENOG502QPUI; Eukaryota.
DR GeneTree; ENSGT00390000008529; -.
DR HOGENOM; CLU_000786_0_0_1; -.
DR InParanoid; F7ILR9; -.
DR TreeFam; TF323227; -.
DR Proteomes; UP000008225; Chromosome 1.
DR Bgee; ENSCJAG00000031332; Expressed in cerebellum and 6 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006325; P:chromatin organization; IEA:InterPro.
DR CDD; cd13839; MEF2_binding; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR033053; Hir3/CABIN1.
DR InterPro; IPR015134; MEF2-bd.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR15502; CALCINEURIN-BINDING PROTEIN CABIN 1-RELATED; 1.
DR PANTHER; PTHR15502:SF7; CALCINEURIN-BINDING PROTEIN CABIN-1; 1.
DR Pfam; PF09047; MEF2_binding; 1.
DR SMART; SM00028; TPR; 5.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 2.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 90..123
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 124..157
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 2120..2154
FT /note="Calcineurin-binding protein cabin-1 MEF2-binding"
FT /evidence="ECO:0000259|Pfam:PF09047"
FT REGION 359..384
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1283..1381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1640..1770
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1793..1812
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1906..1927
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1944..2128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2161..2184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1283..1305
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1313..1332
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1341..1355
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1356..1381
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1714..1729
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1992..2008
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2032..2048
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2050..2072
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2170..2184
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2184 AA; 242582 MW; AAA358829AA102EE CRC64;
MIRIAALNAS STVEDDHEGS FKSHKTQTKE AQEAEAFALY HKALDLQKHD RFEESAKAYH
ELLEARLLRE AVSSGDEKEG LKHPGLILKY STYKNLAQLA AQREDLETAM EFYLEAVMLD
STDVNLWYKI GHVALRLIRI PLARQAFEEG LRCNPDHWPC LDNLITVLYT LSDYTSNGYF
ICRRRQYSLK GITLNTSLYV KFHDMSIHDV SVSAAETQAI VDEALGLRKK RQALIVREKE
PDLKLVQPIP FFTWKCLGES LLAMYNHLTT CEPPRPSLGK RIDLSDYQDP SQPLASSVVV
TPVNVIQPST VRANPAVAVA EPVVSYTSVA TASFPLHSPG LLETGASVGD ISGVDKSKKG
VKRKKISEES GETAKRRSAR VRNTKCKKEE KVDFQELLMK FLPSRLRKLD PEEEDDSFNN
YEVQSEAKLE SFPSIGPHRL SFDSATFMES EKQDVHEFLL ENLTNGGILE LMMRYLKGMG
HKFLLRWPPG LAEVVLSVYH SWRRHSTSLP NPLLRDCSNK HIKDMMLMSL SCMELQLDQW
LLTKGRSSAV SPRNCPAGVV NGRFGPDFPG THCLGDLLQL SFASSQRDLF GDGWLEFVVR
VYWLKARFLA LQGDMEQALE NYDICTEMLQ SSTTIQAEAG AERRDIVIRL PNLHNDSVVS
LEEIDKNLKS LERCQSLEEI QRLYEAGDYK AVVHLLRPTL CTSGFDRAKH LEFMTSIPER
PAQLLLLQDS LIRLKDYRQC FECSDVALNE AVQQMVNSSE AAAKEEWVAT VTQLLMGIEQ
ALSADSSGSI LKESSSTTDL IRLTNNLIQV IDCSMAVQEE AKEPHVSSVL PWIILHRIIW
QEEDTFHSLC HQQQLQNPAE EGMSETPMLP SSLMLLNTAH EYLGRRSWCC NSDGALLRFY
VRVLQKELTA STSEDTHPYK EELETALEQC FYCLYSFPSK KSKARYLEEH SAQQVDLIWE
DALFMFEYFK PKTLPEFDSY KTSTVSADLA NLLKRIATIV PRTERPALSL DKVSAYIEGT
STEVPCLPEG ADPSPPVVNE LYYLLADYHF KNKEQSKAIK FYMHDICICP NRFDSWAGMA
LARASRIQDK LNSNELKSDG PIWKHATPVL NCFRRALEID SSNLSLWIEY GTMSYALHSF
ASRQLKQWRG ELPPELVQQM EGRRDSMLET ARHCFTSAAR CEGDGDEEEW LIHYMLGKVA
EKQQQPPTVY LLHYRQAGHY LHEEAARYPK KIHYHNPPEL AMEALEVYFR LHASILKLLG
KPDSGVGAEV LVNFMKEAAE GPFARGEEKN TPKASEKEKA CLVDEDSHSS AGTLPGPGAS
LPSSSGPGLT SPPYTATPID HDYVKCKKPH QQATPDDRSQ DSTAVALSDS SSTQDFFNEP
TSLLEGSRKS YTEKRLPILS SQAGAIGKNE ECLENTEGFR AAEQGVQKPV AEPPASACIP
GKPSASTPTL WDGKKRGDLA GEPVAFPQGL PAGAEEQRQF LTEQCIASFR LCLSRFPQHY
KSLYRLAFLY TYSKTHRNLQ WARDVLLGSS IPWQQLQHMP AQGLFCERNK TNFFNGIWRI
PVDEIDRPGS FAWHMNRSIV LLLKVLAQLR DHSTLLKVSS MLQRTPDQGK KYLRDADRQV
LAQRAFILTV KVLEDTLSEL AEGSERPGPK VCSLPGARMT TDVSHKATPE DGQEGLPQPK
KPPLTDGSGP GPEPGGKVGL LNHRPVAMDA GDSADQSGER KDKESPRAGL TEPMDTGEAT
ICHSDLERTT PLLPGRPPRD RGPESRPTEL SLEELSISAR QQPTLLTLAQ PAPAPATTMG
TRGGGHPEEP LPRLSRKRKL LEDTESGKTL LLDAYRVWQQ GQKGVAYDLG RVERIMSETY
MLIKQVGGGA AQPTFLTSHL SLQASGDTPT TPKHPKDSRE NFFPAAVAPT APDPMPADSV
QRPSDANTKA RLALAATTAV TTCPPLASAS NLDPSKDPGP PQPHRPEATP SMASLGPEGE
ELARVAEGTS FPPQEPQRSP QVKTAPTSSL EEPHCWPTEA APGTDAEPTC SQEGKLRPEP
RREGEAQEAL SETQPLSFSP TAASSKALSS GTAQPPEGHL GKAEPSRAKS RPLPNMPKLV
IPSAATKFPP EITVTPPTPT LLSPKGSISE ETKQKLKSAI LSAQSAANVR KENLCQPALE
VLETSSQESS LESETDEDDD YMDI
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