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Database: UniProt
Entry: F7IP77_CALJA
LinkDB: F7IP77_CALJA
Original site: F7IP77_CALJA 
ID   F7IP77_CALJA            Unreviewed;       590 AA.
AC   F7IP77;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   20-JUN-2018, sequence version 2.
DT   20-JUN-2018, entry version 46.
DE   SubName: Full=Two pore segment channel 2 {ECO:0000313|Ensembl:ENSCJAP00000029287};
GN   Name=TPCN2 {ECO:0000313|Ensembl:ENSCJAP00000029287};
OS   Callithrix jacchus (White-tufted-ear marmoset).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix.
OX   NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000029287, ECO:0000313|Proteomes:UP000008225};
RN   [1] {ECO:0000313|Ensembl:ENSCJAP00000029287, ECO:0000313|Proteomes:UP000008225}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCJAP00000029287}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUN-2011) to UniProtKB.
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DR   ProteinModelPortal; F7IP77; -.
DR   STRING; 9483.ENSCJAP00000029287; -.
DR   Ensembl; ENSCJAT00000030948; ENSCJAP00000029287; ENSCJAG00000015902.
DR   eggNOG; KOG2301; Eukaryota.
DR   eggNOG; ENOG410XNP6; LUCA.
DR   GeneTree; ENSGT00530000063660; -.
DR   InParanoid; F7IP77; -.
DR   OMA; SSVIWVN; -.
DR   OrthoDB; EOG091G045K; -.
DR   TreeFam; TF328550; -.
DR   Proteomes; UP000008225; Unplaced.
DR   GO; GO:0010008; C:endosome membrane; IEA:Ensembl.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005765; C:lysosomal membrane; IEA:Ensembl.
DR   GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR   GO; GO:0072345; F:NAADP-sensitive calcium-release channel activity; IEA:Ensembl.
DR   GO; GO:0019901; F:protein kinase binding; IEA:Ensembl.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IEA:Ensembl.
DR   GO; GO:0007040; P:lysosome organization; IEA:Ensembl.
DR   GO; GO:0010506; P:regulation of autophagy; IEA:Ensembl.
DR   GO; GO:0006939; P:smooth muscle contraction; IEA:Ensembl.
DR   Gene3D; 1.20.120.350; -; 1.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR028798; TPC2.
DR   InterPro; IPR027359; Volt_channel_dom_sf.
DR   PANTHER; PTHR10037:SF92; PTHR10037:SF92; 1.
DR   Pfam; PF00520; Ion_trans; 2.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008225};
KW   Membrane {ECO:0000256|SAAS:SAAS00085096, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00084820,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00084701,
KW   ECO:0000256|SAM:Phobius}.
SQ   SEQUENCE   590 AA;  66637 MW;  395D4A892B5F18ED CRC64;
     MAEPLAESEP LLGRGRGGGG DCPAGLTTCR SIRVGPGAMA QWDLCVDQAV VFIEDAIQYR
     SINHRMDASS LWLYRRYYSN VCQRTLSFTI FLILFLAFVE TPSSLTRTAD VRYRAAPWEL
     PCGLTQSVEV LCLLVFVADL SVKVRWALGP GPPVPGCRRG RFPGERQGHG KRRERLGTSK
     VLVLGFFSFS VMVPAYSKNR AYAIFFIVFT VIGEKQLLAA VVGWICCDPT PSRGRWMQAG
     RSYVFSAQHP RRPTYQSPFL QSAQFLFGHY YFDYLGNLIA LANLVSICVF LVLDADVLPA
     ERDDFVLGIL NCVFIVYYLL ELLLKVFALG LRGYLSYPSN VFDGLLTIVL LVLEISTLAV
     YRLPHPGWRP EMLGLLSLWD MTRMLNMLIV FRFLRIIPNM KPMAVVASTV LGLVQNMRAF
     GGILVVVYYV FAIIGINLFR GVIVAPLGNS SLAPANGSAP CGSFEQLEYW ANNFDDFAAA
     LVTLWNLMVV NNWQVLLDAF RRYSGPWSKI YFVLWWLVSS VIWVNLFLAL ILENFLHKWD
     PHSYLQPLAG TPEATYQMTV ELMFRDVLEE PKEDELTETL SHHPHLRLCR
//
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