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Database: UniProt
Entry: F7IRZ9_CALJA
LinkDB: F7IRZ9_CALJA
Original site: F7IRZ9_CALJA 
ID   F7IRZ9_CALJA            Unreviewed;      1823 AA.
AC   F7IRZ9; U3B9N7;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   20-JUN-2018, sequence version 2.
DT   05-JUN-2019, entry version 65.
DE   SubName: Full=Laminin subunit alpha-4 isoform 1 {ECO:0000313|EMBL:JAB09453.1};
GN   Name=LAMA4 {ECO:0000313|EMBL:JAB09453.1,
GN   ECO:0000313|Ensembl:ENSCJAP00000008789};
OS   Callithrix jacchus (White-tufted-ear marmoset).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix.
OX   NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000008789, ECO:0000313|Proteomes:UP000008225};
RN   [1] {ECO:0000313|Ensembl:ENSCJAP00000008789, ECO:0000313|Proteomes:UP000008225}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCJAP00000008789}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUN-2011) to UniProtKB.
RN   [3] {ECO:0000313|EMBL:JAB09453.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Bladder {ECO:0000313|EMBL:JAB09453.1};
RX   PubMed=25243066; DOI=10.1186/2047-217X-3-14;
RA   Maudhoo M.D., Ren D., Gradnigo J.S., Gibbs R.M., Lubker A.C.,
RA   Moriyama E.N., French J.A., Norgren R.B.Jr.;
RT   "De novo assembly of the common marmoset transcriptome from NextGen
RT   mRNA sequences.";
RL   Gigascience 3:14-14(2014).
RN   [4] {ECO:0000313|Ensembl:ENSCJAP00000063509}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (APR-2018) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00122}.
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DR   EMBL; GAMT01002408; JAB09453.1; -; mRNA.
DR   STRING; 9483.ENSCJAP00000008789; -.
DR   Ensembl; ENSCJAT00000009291; ENSCJAP00000008789; ENSCJAG00000004703.
DR   Ensembl; ENSCJAT00000070756; ENSCJAP00000063509; ENSCJAG00000004703.
DR   eggNOG; ENOG410IP6G; Eukaryota.
DR   eggNOG; ENOG410Z3D5; LUCA.
DR   GeneTree; ENSGT00940000159970; -.
DR   InParanoid; F7IRZ9; -.
DR   OrthoDB; 2342at2759; -.
DR   TreeFam; TF335359; -.
DR   Proteomes; UP000008225; Unplaced.
DR   GO; GO:0005604; C:basement membrane; IEA:Ensembl.
DR   GO; GO:0031594; C:neuromuscular junction; IEA:Ensembl.
DR   GO; GO:0043083; C:synaptic cleft; IEA:Ensembl.
DR   GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR   GO; GO:0001568; P:blood vessel development; IEA:Ensembl.
DR   GO; GO:0050873; P:brown fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   GO; GO:0120163; P:negative regulation of cold-induced thermogenesis; IEA:Ensembl.
DR   GO; GO:0030155; P:regulation of cell adhesion; IEA:InterPro.
DR   GO; GO:0030334; P:regulation of cell migration; IEA:InterPro.
DR   GO; GO:0045995; P:regulation of embryonic development; IEA:InterPro.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR000742; EGF-like_dom.
DR   InterPro; IPR009254; Laminin_aI.
DR   InterPro; IPR010307; Laminin_dom_II.
DR   InterPro; IPR002049; Laminin_EGF.
DR   InterPro; IPR001791; Laminin_G.
DR   Pfam; PF00053; Laminin_EGF; 3.
DR   Pfam; PF02210; Laminin_G_2; 5.
DR   Pfam; PF06008; Laminin_I; 1.
DR   Pfam; PF06009; Laminin_II; 1.
DR   SMART; SM00181; EGF; 3.
DR   SMART; SM00180; EGF_Lam; 3.
DR   SMART; SM00282; LamG; 5.
DR   SUPFAM; SSF49899; SSF49899; 5.
DR   PROSITE; PS01248; EGF_LAM_1; 1.
DR   PROSITE; PS50027; EGF_LAM_2; 3.
DR   PROSITE; PS50025; LAM_G_DOMAIN; 5.
PE   2: Evidence at transcript level;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008225};
KW   Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00460,
KW   ECO:0000256|SAAS:SAAS00814887};
KW   Laminin EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00460,
KW   ECO:0000256|SAAS:SAAS00580772};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW   Repeat {ECO:0000256|SAAS:SAAS00814929};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     27       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        28   1823       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5018474042.
FT   DOMAIN       82    131       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN      132    186       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN      187    240       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN      833   1035       LAM_G_DOMAIN. {ECO:0000259|PROSITE:
FT                                PS50025}.
FT   DOMAIN     1047   1227       LAM_G_DOMAIN. {ECO:0000259|PROSITE:
FT                                PS50025}.
FT   DOMAIN     1234   1402       LAM_G_DOMAIN. {ECO:0000259|PROSITE:
FT                                PS50025}.
FT   DOMAIN     1469   1640       LAM_G_DOMAIN. {ECO:0000259|PROSITE:
FT                                PS50025}.
FT   DOMAIN     1647   1820       LAM_G_DOMAIN. {ECO:0000259|PROSITE:
FT                                PS50025}.
FT   REGION     1416   1441       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F7IRZ9}.
FT   COILED      339    366       {ECO:0000256|SAM:Coils}.
FT   COILED      381    401       {ECO:0000256|SAM:Coils}.
FT   COILED      478    505       {ECO:0000256|SAM:Coils}.
FT   COILED      587    614       {ECO:0000256|SAM:Coils}.
FT   COILED      666    689       {ECO:0000256|SAM:Coils}.
FT   COILED      705    725       {ECO:0000256|SAM:Coils}.
FT   COILED      785    805       {ECO:0000256|SAM:Coils}.
FT   DISULFID    101    110       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    157    166       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    212    221       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    224    238       {ECO:0000256|PROSITE-ProRule:PRU00460}.
SQ   SEQUENCE   1823 AA;  202656 MW;  593080ECEDFE57D1 CRC64;
     MALSSAWRSV LPLWLLWGAA CSRAASGDDH AFPFDIEGSS AVGRQDPPEL SEPRVALGRL
     PPAAEKCDAG FFHTLSGECV PCDCNGNSNE CLDGSGFCVH CQHNTTGEHC EKCLDGYIGD
     SIRGPPRFCQ PCPCPLPHLA NFAESCYRKN GAVRCICKEN YAGPNCERCA PGYYGNPLLI
     GSTCRKCDCS GNSDPNLIFE DCDEITGQCR NCLRNTTGFN CERCAPGYYG DARIAKNCAV
     CNCGGGPCDS VTGECLEEGF EPPTGMDCPT ISCDKCIWDL TDDLRLAALS IEEGKSGVLS
     VSSGAAAHKH MNEINTTIYL LKTKLSEREN QYALRKIQIN NAENTMKSLL SDVEELVEKE
     NQASRKGQLV YKESMDTINH TSQLVEQAHD MRDKIQEINN KMLYYGEEHE LSPKEVSEKL
     VLAQKMLEEI RRRQPFLTQR ELVGEEADEA HELLSQAESW QRLHNETRTL FPVVLEQLDD
     YNAKLSDLQE ALNQALNHVR DAEDMNRATA ARQRDHEKQQ ERVREQTEVV NRSLSTSADS
     LTTPRLTLSE LDDIIKNASG IYAEIDGAKN ELQVKLSNLS NLSHDLVQEA IDHAQDLQQE
     ANELSRKLHS SDMNGLVQKA LDASNVYENI VNYVSEANET AEFALNTTDR IYDAVSGIDT
     QIIYHKDESE NLLNQARELQ AKAESSSDEA VADTSKRVGG ALARKSALKT RLNDAVKRLQ
     AAERGDAQQR LGQSKLITEE ANRTTMEVQQ ATAPMANNLT NWSQNLQNFD SSAYNTAVDS
     ARDAVRNLTE VVPQLLDQLR TVEQKRPASN VSASIQRIRE LIAQTRSVAS KIQVSMMFDG
     QSAVEVHSRT SMDDLKAFTS LSLYMKPPVK QLELTETADQ FILYLGSKNA KKEYIGLAIK
     NDNLVYVYNL GTKDVEIPLD SKPVSSWPAY FSIVKIERVG KHGKVFLTVP SLSSTAEEKF
     IKKGEFSGDD SLLDLDPEDT VFYVGGVPSN FKLPASLNLP GFVGCLELAT LNNDVISLYN
     FKHIYNMDPS TSVPCARDKL AFTQSRAASY FFDGSSYAAV RNITRRGKFG QVTRFDIEVR
     TTADNGLILL MINGSMFFRL EMRNGYLHVF YDFGFSNGPV HLEDTLKKAQ INDAKYHEIS
     IIYHNDKKLI LVVDRRHVKS MDNEKMKIPF TDIYIGGAPA EILQSRTLRA HLPLDINFRG
     CMKGFQFQKK DFNLLEQTET LGVGYGCPED SLISRRAYFN GQSFIASTQK ISFFDGFEGG
     FNFRTLQPNG LLFYYASGSD VFSISLDNGT VVMNVKGIKV QSVDKQYNDG LSHFVITSVS
     PTRYELIVDK SRLGSKNPTK GKVEQTQPGE KKFYFGGSPI SAQYANFTGC ISNAYFTRVD
     RDVEVEDFQR YTEKVHTSLF ECPIESSPLF LLHKKGKNLS KPKTSQNKKG GKSKDAPSWD
     PVGLKFPEQN TPRNSHCHLS NSPRAIEHAY QYGGTANSRQ EFEHLKEDFG AKSQFSIRLR
     TRSSHGMIFY VSDQEENDFM TLFLAHGRLV FMFNVGHKKL KIRSQEKYND GQWHDVIFIR
     EKSSGRLVID GLRVLEESLP PTGVTWKIKG PIYLGGVAPG KAVKNVQINS IYSFSGCLAH
     LQLNGASITS ASQTFSVTPC FEGPMETGTY FSTEGGYVVL DESFNIGLKF EIAFEVRPRS
     SSGILVHGHS VNGEYLNVHM KNGQVIVKVN NGLRDFSTSV TPKQSLCDGR WHRITVIRDS
     NVVQLDVDSE VNHVVGPLNP QSIDHREPVF VGGVPESLLT PRLAPSKPFT GCIRHFVIDG
     HPVSFSKAAL VSGAVSINSC PAA
//
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