ID F7JN24_9FIRM Unreviewed; 635 AA.
AC F7JN24;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=DNA mismatch repair proteins mutS family domain-containing protein {ECO:0000259|PROSITE:PS00486};
GN ORFNames=HMPREF0988_01632 {ECO:0000313|EMBL:EGN37225.1};
OS Lachnospiraceae bacterium 1_4_56FAA.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=658655 {ECO:0000313|EMBL:EGN37225.1, ECO:0000313|Proteomes:UP000004289};
RN [1] {ECO:0000313|EMBL:EGN37225.1, ECO:0000313|Proteomes:UP000004289}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1_4_56FAA {ECO:0000313|EMBL:EGN37225.1,
RC ECO:0000313|Proteomes:UP000004289};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Brown A.,
RA Chapman S.B., Chen Z., Dunbar C., Freedman E., Gearin G., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heiman D., Howarth C., Larson L., Lui A.,
RA MacDonald P.J.P., Mehta T., Montmayeur A., Murphy C., Neiman D.,
RA Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P.,
RA Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium 1_4_56FAA.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGN37225.1}.
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DR EMBL; ACTN01000011; EGN37225.1; -; Genomic_DNA.
DR AlphaFoldDB; F7JN24; -.
DR STRING; 658655.HMPREF0988_01632; -.
DR PATRIC; fig|658655.3.peg.1660; -.
DR eggNOG; COG1193; Bacteria.
DR HOGENOM; CLU_011252_3_1_9; -.
DR OrthoDB; 9808166at2; -.
DR Proteomes; UP000004289; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR GO; GO:0045910; P:negative regulation of DNA recombination; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR005747; MutS2.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361:SF90; DNA MISMATCH REPAIR PROTEIN; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF005814; MutS_YshD; 2.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000004289}.
FT DOMAIN 402..418
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
SQ SEQUENCE 635 AA; 71767 MW; EA422509F4B5D944 CRC64;
MNNTEKQLEF DKVKAVWKEL ALTEYAKNKI AEMRPILSEN ELSAAIRETS ESKILMEKNG
FPPLDSLQGL KEWVMIAEKG GCLSAEQLEG VEMALTAVSR LKKYLEQGKI YEISLAYYEE
NLDPLTKIRD RIRMQIRSGR VDDQASKLLK TCRNQIEKEE DAMRQKADRA MRAGKSYMAD
SFSTIRNGHL CIPVKKEYKN KVAGIVIDQS STGNTVFMEP AVVSRHYEEI QLLKIREENE
ERRILYELTA YIHDNAEVIE QNIRMIEKLD FIFSKGKLSL EWDAAEPKIN TERKIVLEDG
RHPLMERKSC VPLQFSMGEG TRGVVITGPN TGGKTVAIKT VALNCMMAQC GLHVTCRRAM
ICMNSSFLCD IGDGQNLSEN LSTFSAHIAN VLDILRRING ESLVIMDELG SGTDPTEGMG
IAIAILEELK KSGALFLVTT HYPEVKQYAE HTDGIVNARM TFDKESLKPL YQLVIGEAGE
SCAFYIAGRM GMPKTMLETA AKAAYNGTLP EELKQLCNEE TLKKTHVAKV QKRKTKTAQE
SKSYAFRIGD SVMIYPDKKI GIVCQTANEK GVLRVQMPQK KIWINQKRVK LQVAADQLYP
EDYDFSIVFD TVENRKLRHQ MDRGKCVDGE IRIVL
//
