ID   F7JRY6_9FIRM            Unreviewed;       886 AA.
AC   F7JRY6;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   24-JAN-2024, entry version 53.
DE   RecName: Full=DUF3991 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=HMPREF0988_03090 {ECO:0000313|EMBL:EGN34326.1};
OS   Lachnospiraceae bacterium 1_4_56FAA.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=658655 {ECO:0000313|EMBL:EGN34326.1, ECO:0000313|Proteomes:UP000004289};
RN   [1] {ECO:0000313|EMBL:EGN34326.1, ECO:0000313|Proteomes:UP000004289}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1_4_56FAA {ECO:0000313|EMBL:EGN34326.1,
RC   ECO:0000313|Proteomes:UP000004289};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA   Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA   Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Brown A.,
RA   Chapman S.B., Chen Z., Dunbar C., Freedman E., Gearin G., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heiman D., Howarth C., Larson L., Lui A.,
RA   MacDonald P.J.P., Mehta T., Montmayeur A., Murphy C., Neiman D.,
RA   Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P.,
RA   Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium 1_4_56FAA.";
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGN34326.1}.
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DR   EMBL; ACTN01000023; EGN34326.1; -; Genomic_DNA.
DR   AlphaFoldDB; F7JRY6; -.
DR   STRING; 658655.HMPREF0988_03090; -.
DR   PATRIC; fig|658655.3.peg.3154; -.
DR   eggNOG; COG0358; Bacteria.
DR   eggNOG; COG2856; Bacteria.
DR   HOGENOM; CLU_325362_0_0_9; -.
DR   OrthoDB; 9803716at2; -.
DR   Proteomes; UP000004289; Unassembled WGS sequence.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
DR   CDD; cd01029; TOPRIM_primases; 1.
DR   Gene3D; 3.40.1360.10; -; 1.
DR   InterPro; IPR013610; ArdC_N.
DR   InterPro; IPR025054; DUF3991.
DR   InterPro; IPR010359; IrrE_HExxH.
DR   InterPro; IPR034154; TOPRIM_DnaG/twinkle.
DR   Pfam; PF08401; ArdcN; 1.
DR   Pfam; PF13154; DUF3991; 1.
DR   Pfam; PF06114; Peptidase_M78; 1.
DR   Pfam; PF13155; Toprim_2; 1.
DR   SUPFAM; SSF56731; DNA primase core; 1.
DR   SUPFAM; SSF57783; Zinc beta-ribbon; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000004289}.
FT   DOMAIN          28..117
FT                   /note="N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08401"
FT   DOMAIN          184..255
FT                   /note="IrrE N-terminal-like"
FT                   /evidence="ECO:0000259|Pfam:PF06114"
FT   DOMAIN          468..532
FT                   /note="DUF3991"
FT                   /evidence="ECO:0000259|Pfam:PF13154"
FT   REGION          745..764
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          847..886
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        859..876
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   886 AA;  102968 MW;  45F438CC1A8607F3 CRC64;
     MSENKRPTQA QRQRWKQASM EQQAKMKEMI QTLAESYQEN PENIAELLQF GSKFYRYSVR
     NTMLIYRQNP HATYVQSYKA WKAMGYSPKE GVHGMKVFVP VKTTWLEPEE GKRVQLKYAS
     KEDRIRYQAG EIPGTVRTSY EIGTVFDISQ TTYPPELYPR LYAVGYPSEL HRDVEKGLIA
     YAEERLACPV QVEDLSSISL RGAFYPMENK IRLNERLKDS QRLSTLAHEL GHAMQHREMT
     KSEAQMELEA DALGIMLEQY LGFEPTEARK RHLAECYRSY QEEYRKHPGE RESFGTVMEQ
     VFQKFRQELP KIEQYIQKYV PEQTLQKLSQ PQRGERPEQT NQERYAQIKA QIRIVDYAQQ
     HGYHVVAKGN YYTLKEHDSV IIDPEKNCFW RNSGRGTNPQ GSVIDFAMNF VHSGDLEASL
     EELSQQVGGT SYPVQREREH PATAKTVEKV SLKDHLPERN RDMRRAYAYL TKTRWIDPDV
     VQDFVDRKML YQDVKGNCVF LAYGADGEPN FATFRGTLSE RKFLGDIRGS DYTHDFYISN
     GADKLIVTES VIDAMSVMSI LKGQNHDFQG YDYLVQAGTK KYDAVLTQLQ EHPEVNEVLL
     AMDHDIAGVK GMQKVQELIG EFPEERKVSI HVPDPQYKDW NEVLSTAMRK MQPLEQIPFL
     REGELPEIHF CAVQSTEQVE ERGFRKRGDQ EQYRLVEIGS EGQIQPMEIN RNVIYTDPEQ
     LKPLVPKMYE LVKYEELEEQ RAFRMEQSRE TEQKQIEAPS QESGKKLAAE QIRVENGLVM
     AEVQLDGQRE TLAVSREGNR YYVETGYAFD ETLQEHDLDE HAAEQIREQL GGRMEELGEG
     LLYLEDPLPE SPRKSSPFLE RVQQEEQKKA EMGMEYQPEE AMEMML
//