ID F7KC93_9FIRM Unreviewed; 873 AA.
AC F7KC93;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 2.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=beta-glucosidase {ECO:0000256|ARBA:ARBA00012744};
DE EC=3.2.1.21 {ECO:0000256|ARBA:ARBA00012744};
GN ORFNames=HMPREF0994_03472 {ECO:0000313|EMBL:EGN39545.2};
OS Lachnospiraceae bacterium 3_1_57FAA_CT1.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=658086 {ECO:0000313|EMBL:EGN39545.2, ECO:0000313|Proteomes:UP000003336};
RN [1] {ECO:0000313|Proteomes:UP000003336}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3_1_57FAA_CT1 {ECO:0000313|Proteomes:UP000003336};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Brown A.,
RA Chapman S.B., Chen Z., Dunbar C., Freedman E., Gearin G., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heiman D., Howarth C., Larson L., Lui A.,
RA MacDonald P.J.P., Mehta T., Montmayeur A., Murphy C., Neiman D.,
RA Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P.,
RA Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium 2_1_58FAA.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EGN39545.2, ECO:0000313|Proteomes:UP000003336}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3_1_57FAA_CT1 {ECO:0000313|EMBL:EGN39545.2,
RC ECO:0000313|Proteomes:UP000003336};
RG The Broad Institute Genomics Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA Allen-Vercoe E., Walker B., Young S., Zeng Q., Gargeya S., Fitzgerald M.,
RA Haas B., Abouelleil A., Allen A.W., Alvarado L., Arachchi H.M.,
RA Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A., Larimer J.,
RA McCowan C., Murphy C., Pearson M., Poon T.W., Priest M., Roberts A.,
RA Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium 3-1-57FAA CT1.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing beta-D-glucosyl residues
CC with release of beta-D-glucose.; EC=3.2.1.21;
CC Evidence={ECO:0000256|ARBA:ARBA00000448};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGN39545.2}.
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DR EMBL; ACTP02000012; EGN39545.2; -; Genomic_DNA.
DR AlphaFoldDB; F7KC93; -.
DR STRING; 658086.HMPREF0994_03472; -.
DR eggNOG; COG1472; Bacteria.
DR HOGENOM; CLU_004542_5_1_9; -.
DR Proteomes; UP000003336; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 2.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR026891; Fn3-like.
DR InterPro; IPR002772; Glyco_hydro_3_C.
DR InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR037524; PA14/GLEYA.
DR InterPro; IPR011658; PA14_dom.
DR PANTHER; PTHR30620:SF16; LYSOSOMAL BETA GLUCOSIDASE; 1.
DR PANTHER; PTHR30620; PERIPLASMIC BETA-GLUCOSIDASE-RELATED; 1.
DR Pfam; PF14310; Fn3-like; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR Pfam; PF01915; Glyco_hydro_3_C; 1.
DR Pfam; PF07691; PA14; 1.
DR PRINTS; PR00133; GLHYDRLASE3.
DR SMART; SM01217; Fn3_like; 1.
DR SMART; SM00758; PA14; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF56988; Anthrax protective antigen; 1.
DR SUPFAM; SSF52279; Beta-D-glucan exohydrolase, C-terminal domain; 1.
DR PROSITE; PS51820; PA14; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000003336}.
FT DOMAIN 473..611
FT /note="PA14"
FT /evidence="ECO:0000259|PROSITE:PS51820"
SQ SEQUENCE 873 AA; 96098 MW; 7F4C0B2DBA399C11 CRC64;
MENYKNPNLS IEERTADLLS RMTLEEKIKQ TDQFYVYDFA EISPEGRVIE PDMDAMDKLM
GGMSVGSVQL RGCSPRIANQ LQRYAVEKTR LGIPFLYSEE ALHGFFDAHA TCFPQQISLA
ASFQPELGKE MGHCIAAEAR AYGVHETFSP VMDLTRDPRY GRVEESFGED TYLCGEFARE
IVKGMQGADL KAPDTVAAEP KHYVGYGTPV AGLNCAPSAM GRRDIFAYCM PVFEEAFVNG
GAWNAMCSYN SIDGQPVSSD HEILTDVLRG QFRMPGFVRS DMTAVSRLYD WHFTAPSKPD
AIRQGLEAGV DLQLYDFTHE EWTEGIRSLI REGKMQETVL DTACGRVLKL KFALGLFENP
YVDEGLYEKT ANCPAHQETA ADIARKSICL LKNKDGMLPL SRDLKTIAVI GPGANEPALG
DYCTGYDPQH MVTVLDGIRQ LAGESTRILY EKGCSYLGEQ LIPFHPGWFI SEDGASGLTG
RYYNGWKMEG EPVTTRVDSM IRFNWIYAKP HPDVDAAFFS VVWTGTLKAP ESFSGCLGLS
GMDSMRLYVD GTLLLDSWGV SDKDGLLTDF TFEAGREYAI RLEFCNDARG ARVIFGYNRG
RDNTEAAVKA AKSADVAIVC LGDNTETSGE NLDRTELTLP GGQLDFLKKI AAAGTPVVLV
LQNGRPLSLT WEQEHIPAIV EAWFPGEKGG RAIAEILFGI TAPSGRLPMS FPKSAGQIPC
NYNRFPGGGK RYVEMDWEPL YPFGFGLTYT SFAYSGLAIS GDGLTAGEVE KGAEILISFT
VTNTGTVFGE ETAQVYVRDV CASVVKPVKE LAGFEKAALQ PGESRLIRIP LGRRQLRTLN
MQYQWHVEPG DFEVMVGDNA ANVLLAGGFR LAE
//
