ID F7KQS0_9FIRM Unreviewed; 793 AA.
AC F7KQS0;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Helicase ATP-binding domain-containing protein {ECO:0000259|PROSITE:PS51193};
GN ORFNames=HMPREF0993_01313 {ECO:0000313|EMBL:EGN39621.1};
OS Lachnospiraceae bacterium 5_1_57FAA.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=658085 {ECO:0000313|EMBL:EGN39621.1, ECO:0000313|Proteomes:UP000005617};
RN [1] {ECO:0000313|EMBL:EGN39621.1, ECO:0000313|Proteomes:UP000005617}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=5_1_57FAA {ECO:0000313|EMBL:EGN39621.1,
RC ECO:0000313|Proteomes:UP000005617};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Brown A.,
RA Chapman S.B., Chen Z., Dunbar C., Freedman E., Gearin G., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heiman D., Howarth C., Larson L., Lui A.,
RA MacDonald P.J.P., Mehta T., Montmayeur A., Murphy C., Neiman D.,
RA Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P.,
RA Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium 5_1_57FAA.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the helicase family. DinG subfamily.
CC {ECO:0000256|ARBA:ARBA00038058}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGN39621.1}.
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DR EMBL; ACTR01000010; EGN39621.1; -; Genomic_DNA.
DR RefSeq; WP_009248584.1; NZ_AP024846.1.
DR AlphaFoldDB; F7KQS0; -.
DR GeneID; 69694263; -.
DR PATRIC; fig|658085.3.peg.1356; -.
DR HOGENOM; CLU_006515_7_0_9; -.
DR Proteomes; UP000005617; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR Gene3D; 1.10.275.40; -; 1.
DR Gene3D; 3.90.320.10; -; 1.
DR Gene3D; 1.10.30.20; Bacterial XPD DNA helicase, FeS cluster domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR006555; ATP-dep_Helicase_C.
DR InterPro; IPR045028; DinG/Rad3-like.
DR InterPro; IPR014013; Helic_SF1/SF2_ATP-bd_DinG/Rad3.
DR InterPro; IPR006554; Helicase-like_DEXD_c2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011604; PDDEXK-like_dom_sf.
DR InterPro; IPR010614; RAD3-like_helicase_DEAD.
DR InterPro; IPR042493; XPD_DNA_FeS.
DR PANTHER; PTHR11472; DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER; 1.
DR PANTHER; PTHR11472:SF47; FANCONI ANEMIA GROUP J PROTEIN; 1.
DR Pfam; PF06733; DEAD_2; 1.
DR Pfam; PF13307; Helicase_C_2; 1.
DR SMART; SM00488; DEXDc2; 1.
DR SMART; SM00491; HELICc2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51193; HELICASE_ATP_BIND_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000005617}.
FT DOMAIN 184..465
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51193"
FT COILED 421..471
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 793 AA; 92067 MW; F7218186C5ACE1CD CRC64;
MDLEQPVIRS SVRSLVEFIL RGGDIDNRIA GTDKDAMLLG GKIHRKIQRQ MGADYHAEVS
LKQEVACNGF LLLIEGRADG IMDTPQGPVV DEIKGIFKEL DTLKEPILVH LAQAKCYAYI
YARQNGLEEI GVQMTYCNME TEEIKRFQST YAFEELEAWF QELTASYERW ARYQIEWRKK
RNASIRQVEF PFSYREGQKE LVTSVYRTIL RKKKLFVQAP TGVGKTISTV FPAVKAMGEG
LGEKIFYLTA KTITRTVAWQ AFDSLKAQDL RMKVIVLTAK EKICFCEETN CNPDDCPYAK
GHFDRVNDAV YELLASTDEM SREVIEEQAR KWNVCPFEMG LDVSLWVDAI ICDYNYVFDP
NAHLKRFFGE GNKGEYLFLI DEAHNLVDRG REMYSASIYK EDFLKIKRLV KAEDSRLASR
LDECNKQLLA LKRECEDYQI LDSVAHIYLK LLALMTEMER YLEECRNEEI RKEVLELYFA
VRMFANIHEG LDENYLIYSE LEEDGRFKLR LFCVNPANCL AQFLDRGNST VFFSATLLPI
HYYKKLLSNS KEDYAIYAES PFDARKRLLL IGTDVSTKYT SRGEEMYRRY AEYLIQVARS
RKGNYIAFFP SYYFMEEVYG VFVSLLESVP FYGGRKIEYV MQSRYMSEEA REIFLENFEE
DKDNSLMGFC VMGGIFSEGI DLAMDKLIGA IIVGTGLPQV CRERELLKTY FDSHGLRGFD
YAYLYPGMNK VLQSAGRVIR TDQDCGIILL LDERFRDGRY QETFPREWSQ YGWCNARNVT
GMIETFWDGM DKA
//
