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Database: UniProt
Entry: F7KU80_9FIRM
LinkDB: F7KU80_9FIRM
Original site: F7KU80_9FIRM 
ID   F7KU80_9FIRM            Unreviewed;       295 AA.
AC   F7KU80;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   28-FEB-2018, entry version 31.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGN36880.1};
GN   ORFNames=HMPREF0993_02518 {ECO:0000313|EMBL:EGN36880.1};
OS   Lachnospiraceae bacterium 5_1_57FAA.
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Lachnospiraceae.
OX   NCBI_TaxID=658085 {ECO:0000313|EMBL:EGN36880.1, ECO:0000313|Proteomes:UP000005617};
RN   [1] {ECO:0000313|EMBL:EGN36880.1, ECO:0000313|Proteomes:UP000005617}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=5_1_57FAA {ECO:0000313|EMBL:EGN36880.1,
RC   ECO:0000313|Proteomes:UP000005617};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA   Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M.,
RA   Haas B., Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.,
RA   Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E., Gearin G.,
RA   Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D., Howarth C.,
RA   Larson L., Lui A., MacDonald P.J.P., Mehta T., Montmayeur A.,
RA   Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S.,
RA   Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium 5_1_57FAA.";
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EGN36880.1}.
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DR   EMBL; ACTR01000026; EGN36880.1; -; Genomic_DNA.
DR   RefSeq; WP_009249311.1; NZ_GL945257.1.
DR   EnsemblBacteria; EGN36880; EGN36880; HMPREF0993_02518.
DR   PATRIC; fig|658085.3.peg.2617; -.
DR   OrthoDB; POG091H02BQ; -.
DR   BioCyc; LBAC658085-HMP:GMJC-2569-MONOMER; -.
DR   Proteomes; UP000005617; Unassembled WGS sequence.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
DR   Gene3D; 1.10.1040.10; -; 1.
DR   InterPro; IPR002204; 3-OH-isobutyrate_DH-rel_CS.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR006115; 6PGDH_NADP-bd.
DR   InterPro; IPR015815; HIBADH-related.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR029154; NADP-bd.
DR   Pfam; PF14833; NAD_binding_11; 1.
DR   Pfam; PF03446; NAD_binding_2; 1.
DR   PIRSF; PIRSF000103; HIBADH; 1.
DR   SUPFAM; SSF48179; SSF48179; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00895; 3_HYDROXYISOBUT_DH; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005617};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005617}.
FT   DOMAIN        2    157       NAD_binding_2. {ECO:0000259|Pfam:
FT                                PF03446}.
FT   DOMAIN      163    282       NAD_binding_11. {ECO:0000259|Pfam:
FT                                PF14833}.
FT   ACT_SITE    169    169       {ECO:0000256|PIRSR:PIRSR000103-1}.
SQ   SEQUENCE   295 AA;  30820 MW;  88FB3C5C3E059D56 CRC64;
     MKVGFIGLGI MGRPMAKNMV KAGVDLMVAD LNKEAVADVV AAGAKEGTYA QIGAECGVVF
     TIVPNGDIVK SILFDEGGVA STLKAGSIVC DMSSVTPVES KECYTRLKEK GVGFIDAPVS
     GGEPGAVAGT LAIMAGGEEK DFQALKEYFD ILGSSALLIG GSGSGSVTKL ANQIIVNNTI
     AVVSEAFVLA AKAGADPQKV YEAIRGGLAG SAVLDAKIPM IVERNFKPGG PIRINHKDIK
     NVVNTAHAVD VPIPYTAQLY EILQTLKIHG HMEDDHAGIV QYFEKLADVE VKKFD
//
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